ID | 63759 |
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Author |
Nomura, Emi
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Omote, Yoshio
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Takemoto, Mami
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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Hishikawa, Nozomi
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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Nakano, Yumiko
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Yunoki, Taijun
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Morihara, Ryuta
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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Sasaki, Tatsuya
Department of Neurological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Akagawa, Hiroyuki
Tokyo Women's Medical University Institute for Integrated Medical Sciences
Abe, Koji
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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Yamashita, Toru
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University
ORCID
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Abstract | Cerebral cavernous malformations (CCMs) are congenital abnormalities of cerebral vessels. Surgical resection is rarely considered for the control of epilepsy in a first seizure patient with vascular malformation. In contrast, lesions that produce repetitive or progressive symptoms should be considered for surgical resection as treatment. Herein, we report a Japanese patient with a CCM2 mutation, c.609G>A (p.K203K) substitution, who showed drug-resistant epilepsy and dramatic improvement after surgical resection.
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Keywords | CCM2
cerebral cavernous malformation
drug-resistant epilepsy
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Note | This is the peer reviewed version of the following article: [Nomura, E, Omote, Y, Takemoto, M, et al. A Japanese case of successful surgical resection of cerebral cavernous malformations with a CCM2 mutation. Neurol Clin Neurosci. 2022; 10: 255- 258. doi: 10.1111/ncn3.12649], which has been published in final form at [https://doi.org/10.1111/ncn3.12649]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
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Published Date | 2022-06-15
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Publication Title |
Neurology and Clinical Neuroscience
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Volume | volume10
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Issue | issue5
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Publisher | Wiley
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Start Page | 255
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End Page | 258
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ISSN | 2049-4173
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Content Type |
Journal Article
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language |
English
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OAI-PMH Set |
岡山大学
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Copyright Holders | © 2022 Japanese Society of Neurology and John Wiley & Sons Australia, Ltd.
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File Version | author
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DOI | |
Web of Science KeyUT | |
Related Url | isVersionOf https://doi.org/10.1111/ncn3.12649
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Citation | Nomura, E, Omote, Y, Takemoto, M, et al. A Japanese case of successful surgical resection of cerebral cavernous malformations with a CCM2 mutation. Neurol Clin Neurosci. 2022; 10: 255- 258. doi: 10.1111/ncn3.12649
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Funder Name |
Japan Agency for Medical Research and Development
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