Title Alternative Damus-Kaye-Stansel anastomosis
FullText URL 124_9.pdf
Author Fujii, Yasuhiro| Sano, Shunji| Arai, Sadahiko| Kasahara, Shingo| Tateishi, Atsushi| Takagaki, Masami| Fujita, Yasufumi| Ozawa, Susumu|
Keywords Damus-Kaye-Stansel吻合 単心室症 心室流出路狭窄 肺動脈弁逆流
Publication Title 岡山医学会雑誌
Published Date 2012-04-01
Volume volume124
Issue issue1
Start Page 9
End Page 13
ISSN 0030-1558
language Japanese
Copyright Holders Copyright (c) 2012 岡山医学会
File Version publisher
DOI 10.4044/joma.124.9
NAID 130004505753
JaLCDOI 10.18926/AMO/32179
FullText URL fulltext.pdf
Author Murakami, Taiji| Ishino, Kozo| Nakayama, Hironobu| Kino, Koichi| Arai, Sadahiko| Nakayama, Yorikazu| Sugawara, Eiji| Senoo, Yoshimasa| Teramoto, Shigeru|
Abstract

Over the last three years, we have used ventricular assist devices (VAD) in 7 patients. Of these 7, four patients with combined aortic and mitral valvular disease underwent double valve replacement; one patient with annuloaortic ectasia underwent a Cabrol's operation; another had aortic valve replacement; the last patient had triple coronary artery bypass grafts. The only patient who could be weaned from CPB developed cardiogenic shock after the operation. LVADs supported 6 patients for 4 to 8 days and a BVAD supported one patient for 9 days. All patients survived the weaning procedure. Three were discharged from the hospital and survived 7 to 21 months. The 4 other patients died of multiple organ failure. Three of these four suffered from both renal failure and infection, while one patient had arrhythmia and died of ileus. These data suggest that renal failure and major infection can be serious detrimental complications to VAD support.

Keywords ventricular assist device postcaediotomy shock multiorgan failure
Amo Type Article
Publication Title Acta Medica Okayama
Published Date 1991-12
Volume volume45
Issue issue6
Publisher Okayama University Medical School
Start Page 433
End Page 440
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 1781299
Web of Science KeyUT A1991GX45300005
JaLCDOI 10.18926/AMO/31592
FullText URL fulltext.pdf
Author Kohmoto, Takushi| Arai, Sadahiko| Senoo, Yoshimasa| Teramoto, Shigeru|
Abstract

To assess the usefulness of flowcytometric monitoring in the early detection of acute allograft rejection, we studied surface markers of graft infiltrating lymphocytes, coronary sinus blood lymphocytes and peripheral blood lymphocytes after rat heart transplantation. Fisher rats served as donors and Lewis rats as recipients. Among recipients that received no immunosuppression, grafts were removed 2 days after transplantation (Ongoing Rejection Group: n = 7) and on the day of terminal rejection (Rejection Group: n = 7). The Immunosuppression Group (n = 7) was treated with cyclosporine A at a dose of 3 mg/kg/day intramuscularly for 14 days. The following two color analyses were studied: OX8 (anti-CD8) with OX39 (anti-interleukin 2 receptor; IL2R), W3/25 (anti-CD4) with OX39, W3/25 with OX8. Histological grading demonstrated no significant difference between the Ongoing Rejection Group and the Immunosuppression Group, which showed mild rejection (1.29 +/- 0.27 versus 1.14 +/- 0.24). The proportion of CD8(+)IL2R(+) graft infiltrating lymphocytes showed a more significant increase in the Ongoing Rejection Group than in the Immunosuppression Group (32.1 +/- 3.05 versus 20.6 +/- 9.02; p < 0.01). The proportion of CD8(+) IL2R(+) coronary sinus blood lymphocytes also showed significant increase in the Ongoing Rejection Group compared with the Immunosuppression Group (4.63 +/- 1.91 versus 2.52 +/- 1.60; p < 0.05). These results suggest that this technique can detect acute allograft rejection earlier than endomyocardial biopsy, before the phase in which histological findings become evident.

Keywords acute rejection heart transplantation flowcytometry immunologic monitoring interleukin 2 receptor
Amo Type Article
Publication Title Acta Medica Okayama
Published Date 1993-06
Volume volume47
Issue issue3
Publisher Okayama University Medical School
Start Page 145
End Page 150
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 8379342
Web of Science KeyUT A1993LL12400002
Author 新井 禎彦|
Published Date 1992-09-30
Publication Title
Content Type Thesis or Dissertation