ID | 31132 |
JaLCDOI | |
FullText URL | |
Author |
Fujiwara, Takuzo
Sakagami, Kenichi
Uda, Masashi
Orita, Kunzo
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Abstract | The antidonor immune response was examined in a one haplotype-mismatched renal transplant recipient with an allograft that had been well-functioning for more than 10 years. Although the relative response of the mixed lymphocyte reaction (MLR) was (45.8)% and the MLR responder cells stimulated by donor cells produced measurable amounts of interleukin-2 (IL-2) (11.6 U/ml), the cytotoxic T lymphocytes (CTL) could not be generated against donor cells, even with exogenous IL-2. These results indicate that antidonor CTL precursors were either deleted or inactivated in this recipient. |
Keywords | renal transplantation
long-term stable recipient
cytotoxic T lymphocytes
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Amo Type | Article
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Publication Title |
Acta Medica Okayama
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Published Date | 1994-02
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Volume | volume48
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Issue | issue1
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Publisher | Okayama University Medical School
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Start Page | 63
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End Page | 65
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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File Version | publisher
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Refereed |
True
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PubMed ID | |
Web of Science KeyUT |