| ID | 51551 |
| FullText URL | |
| Author |
Ejiri, Kazumasa
Yamamoto, Hiroshi
|
| Abstract | The key precursor, N-2-(N,N-dimethylaminomethylene)-6-hydroxymethy1-8-methyl-3[2-(4-nitrophenypethyl]-7-xanthopterin (9) was efficiently prepared from 2,5-diamino-6-methylam1no-3H-pyrimidin-4-one (3) and ethyl 3-(tert-butyldimethylsilyloxy)-2-oxopropionate (11). The first synthesis of asperopterin-A (2b) was achieved by treatment of 9 with 1-O-acetyl-2,3,5-tri-O-benzoy1-beta-D-ribofuranose (15) in the presence of tin(IV) chloride, followed by removal of the protecting groups.
|
| Keywords | Isoxanthopterin Glycoside
Glycosylation
Pteridine
Hydroxymethylation
Protecting Group
|
| Published Date | 2012-01-01
|
| Publication Title |
Heterocycles
|
| Volume | volume84
|
| Issue | issue2
|
| Start Page | 801
|
| End Page | 813
|
| ISSN | 1881-0942
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| Content Type |
Journal Article
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| Official Url | http://www.heterocycles.jp/newlibrary/libraries/abst/21903
|
| language |
English
|
| Copyright Holders | © 2012 The Japan Institute of Heterocyclic Chemistry
|
| File Version | author
|
| Refereed |
True
|
| DOI | |
| Web of Science KeyUT |
