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ID 48911
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Author
Fukuhara, Kazuma
Phompida, Samlane
Insisiengmay, Sithat
Kirinoki, Masashi
Chigusa, Yuichi
Nakamura, Satoshi
Matsuda, Hajime
Abstract
Schistosomiasis mekongi is prevalent in the Khong district of Lao PDR, made up of one big island. Khong, and numerous small islands in the Mekong River. Schistosoma mekongi is spread by Neotricula aperta as the intermediate host along the Mekong River. Therefore, even if an epidemic of S. mekongi were stamped out in a certain village, infection may recur if the source of infection is a village located in the upper reaches of the Mekong River. The purpose of this study was to construct a mathematical model for the transmission of S. mekongi among villages from the upper to lower Mekong River to estimate the effect of control measures against it. The chief characteristic of the present model is competence in dealing with the spread of infection among villages through the Mekong River in consideration of the reduction in longevity of cercariae and miracidia and their diffusion in the river. The model also takes into account seasonal fluctuation in the water level of the Mekong River, which affects human behavior in terms of water contact. The results of simulations indicated that the prevalence of schistosomiasis mekongi would be suppressed to a low level for a long time in a village further downstream when universal mass treatment is performed in villages further upstream simultaneously.
Keywords
Schistosoma mekongi
Khong; Mekong River
Mathematical model
Universal mass treatment (UT)
Published Date
2011-12
Publication Title
Parasitology International
Volume
volume60
Issue
issue4
Start Page
452
End Page
459
ISSN
1383-5769
Content Type
Journal Article
Official Url
http://www.sciencedirect.com/science/article/pii/S1383576911001152
language
英語
Copyright Holders
© 2011 Elsevier Ireland Ltd. All rights reserved.
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author
Refereed
True
DOI
PubMed ID
Web of Sience KeyUT