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ID 34113
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Author
Nishina, Tomohiko
Abstract

Echinococcus multilocularis causes human alveolar echinococcus. In Japan, high prevalence of E. multilocularis among the fox population has been reported throughout Hokkaido. Accordingly, control measures, such as fox hunting and the distribution of bait containing Praziquantel, have been conducted. This study developed a transmission model for individuals in the fox population and included a stochastic infection process to assess the prevalence of E. multilocularis. To make our model realistic, we used the worm burden for each individual in the fox population. We assumed that the worm burden depends on the number of protoscoleces in a predated vole and the number of infection experiences. We carried out stochastic simulations with 1,000 trials for the situations of Koshimizu and Sapporo, Hokkaido, Japan. The distribution of the worm burden among foxes obtained using the model agreed with dissection data. The simulation indicates that a careful choice of season is necessary for an effective distribution of Praziquantel-containing bait. A stochastic model for E. multilocularis, which can assess the range of the prevalence in the fox population, would be helpful in analyzing their complex life-cycle and also in designing control strategies.

Keywords
Echinococcus multilocularis
stochastic model
control strategy
Hokkaido
Note
Digital Object Identifer:10.1007/s00436-007-0787-1
This is an author-created version, as published in Parasitology Research, 2008, Volume 102, Issue 3, Pages 465-479.
The final publication is available at www.springerlink.com.
Publisher URL:http://dx.doi.org/10.1007/s00436-007-0787-1
Direct access to Thomson Web of Science record
Copyright © Springer-Verlag 2007 All rights reserved.
Published Date
2008-02-01
Publication Title
Parasitology Research
Volume
volume102
Issue
issue3
Start Page
465
End Page
479
Content Type
Journal Article
language
英語
Refereed
True
DOI
Web of Sience KeyUT
Submission Path
microbiology_and_immunology/14