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ID 47265
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Author
Harada, Sosuke
Okumura, Yoshihiro
Mimura, Hidefumi
Kanazawa, Susumu Kaken ID
Kaji, Mitsumasa
Fujiwara, Toshiyoshi ORCID Kaken ID
Abstract
The aim of the present study was to assess the diagnostic usefulness of Fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) in the prediction of local recurrence of malignant lung tumors by analyzing the pre-radiofrequency ablation (RFA) maximal standardized uptake value (SUVmax). We performed a historical cohort study of consecutive malignant lung tumors treated by RFA from January 2007 to May 2008 at Okayama University Hospital. We selected only lung tumors examined by PET/CT within 90 days before RFA and divided them (10 primary and 29 metastatic) into 3 groups according to their tertiles of SUVmax. We calculated recurrence odds ratios in the medium group and the high group compared to the low group using multivariate logistic analysis. After we examined the relationship between SUVmax and recurrence in a crude model, we adjusted for some factors. Tumors with higher SUVmax showed higher recurrence odds ratios (medium group;1.84, high group;4.14, respectively). The tumor size also increased the recurrence odds ratio (2.67);we thought this was mainly due to selection bias because we excluded tumors less than 10mm in diameter. This study demonstrated the pre-RFA SUVmax in PET/CT may be a prognostic factor for local recurrence of malignant lung tumors.
Keywords
fluorodeoxyglucose (FDG)
positron emission tomography (PET)
standardized uptake value (SUV)
radiofrequency ablation (RFA)
lung
Amo Type
Original Article
Published Date
2011-12
Publication Title
Acta Medica Okayama
Volume
volume65
Issue
issue6
Publisher
Okayama University Medical School
Start Page
395
End Page
402
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
CopyrightⒸ 2011 by Okayama University Medical School
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publisher
Refereed
True
PubMed ID
Web of Science KeyUT