| FullText URL | fulltext.pdf |
|---|---|
| Author | Tanaka, Keiko| Sugiyama, Hitoshi| Morinaga, Hiroshi| Onishi, Akifumi| Tanabe, Katsuyuki| Uchida, Haruhito A.| Maruyama, Hiroki| Wada, Jun| |
| Keywords | Fabry disease R112H mutation migalastat proteinuria chronic kidney disease |
| Published Date | 2024-06-06 |
| Publication Title | Frontiers in Medicine |
| Volume | volume11 |
| Publisher | Frontiers Media |
| Start Page | 1383309 |
| ISSN | 2296-858X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 Tanaka, Sugiyama, Morinaga, Onishi, Tanabe, Uchida, Maruyama and Wada. |
| File Version | publisher |
| PubMed ID | 38903807 |
| DOI | 10.3389/fmed.2024.1383309 |
| Web of Science KeyUT | 001250041200001 |
| Related Url | isVersionOf https://doi.org/10.3389/fmed.2024.1383309 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ueno, Asami| Onishi, Yasuhiro| Mise, Koki| Yamaguchi, Satoshi| Kanno, Ayaka| Nojima, Ichiro| Higuchi, Chigusa| Uchida, Haruhito A.| Shikata, Kenichi| Miyamoto, Satoshi| Nakatsuka, Atsuko| Eguchi, Jun| Hida, Kazuyuki| Katayama, Akihiro| Watanabe, Mayu| Nakato, Tatsuaki| Tone, Atsuhito| Teshigawara, Sanae| Matsuoka, Takashi| Kamei, Shinji| Murakami, Kazutoshi| Shimizu, Ikki| Miyashita, Katsuhito| Ando, Shinichiro| Nunoue, Tomokazu| Wada, Jun| |
| Published Date | 2024-05 |
| Publication Title | BMJ Open Diabetes Research and Care |
| Volume | volume12 |
| Issue | issue3 |
| Publisher | BMJ Publishing Group |
| Start Page | e004237 |
| ISSN | 2052-4897 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Author(s) (or their employer(s)) 2024. |
| File Version | publisher |
| PubMed ID | 38816205 |
| DOI | 10.1136/bmjdrc-2024-004237 |
| Web of Science KeyUT | 001236385500001 |
| Related Url | isVersionOf https://doi.org/10.1136/bmjdrc-2024-004237 |
| Title Alternative | The 53rd Western Regional Meeting of the Japanese Society of Nephrology |
|---|---|
| Author | Wada, Jun| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2024-04-01 |
| Volume | volume136 |
| Issue | issue1 |
| Start Page | 37 |
| End Page | 37 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.136.37 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2024 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.136.37 |
| JaLCDOI | 10.18926/AMO/66927 |
|---|---|
| FullText URL | 78_2_185.pdf |
| Author | Takahashi, Hiroko| Eguchi, Jun| Watanabe, Mayu| Nakayama, Masanori| Wada, Jun| |
| Abstract | The global pandemic of coronavirus infection 2019 (COVID-19) was an unprecedented public health emergency. Several clinical studies reported that heart disease, lung disease, diabetes, hypertension, dyslipidemia, and obesity are critical risk factors for increased severity of and hospitalization for COVID-19. This is largely because patients with these underlying medical conditions can show poor immune responses to the COVID-19 vaccinations. Diabetes is one of the underlying conditions most highly associated with COVID-19 susceptibility and is considered a predictor of poor prognosis of COVID-19. We therefore investigated factors that influence the anti-SARS-CoV-2 spike IgG antibody titer after three doses of vaccination in patients with type 2 diabetes. We found that obesity was associated with low anti-SARS-CoV-2 spike IgG antibody titers following three-dose vaccination in type 2 diabetics. Obese patients with type 2 diabetes may have attenuated vaccine efficacy and require additional vaccination; continuous infection control should be considered in such patients. |
| Keywords | obesity type 2 diabetes COVID-19 vaccination |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-04 |
| Volume | volume78 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 185 |
| End Page | 191 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38688836 |
| Web of Science KeyUT | 001227932200002 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kano, Yuzuki| Yamaguchi, Satoshi| Mise, Koki| Kawakita, Chieko| Onishi, Yasuhiro| Kurooka, Naoko| Sugawara, Ryosuke| Albuayjan, Haya Hamed Hassan| Nakatsuka, Atsuko| Eguchi, Jun| Wada, Jun| |
| Keywords | diabetes mellitus diabetic nephropathy metabolism obesity tubular epithelium |
| Published Date | 2023-12-08 |
| Publication Title | Kidney360 |
| Volume | volume5 |
| Issue | issue2 |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Start Page | 182 |
| End Page | 194 |
| ISSN | 2641-7650 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | Copyright © 2023 The Author(s). |
| File Version | publisher |
| PubMed ID | 38062578 |
| DOI | 10.34067/kid.0000000000000333 |
| Web of Science KeyUT | 001178403800002 |
| Related Url | isVersionOf https://doi.org/10.34067/kid.0000000000000333 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsumoto, Kazuya| Miyawaki, Yoshia| Katsuyama, Takayuki| Nakadoi, Takato| Shidahara, Kenta| Hirose, Kei| Nawachi, Shoichi| Asano, Yosuke| Katayama, Yu| Katsuyama, Eri| Takano-Narazaki, Mariko| Matsumoto, Yoshinori| Mori, Atsushi| Akagi, Satoshi| Sada, Ken-Ei| Wada, Jun| |
| Keywords | pulmonary arterial hypertension anti-U1 RNP antibody corticosteroid cyclophosphamide |
| Published Date | 2024-03-01 |
| Publication Title | Internal Medicine |
| Volume | volume63 |
| Issue | issue5 |
| Publisher | Japanese Society of Internal Medicine |
| Start Page | 671 |
| End Page | 676 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 37468249 |
| DOI | 10.2169/internalmedicine.1407-22 |
| Web of Science KeyUT | 001179673600001 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.1407-22 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsumoto, Kazuya| Matsumoto, Yoshinori| Nawachi, Shoichi| Asano, Yosuke| Katayama, Yu| Miyawaki, Yoshia| Katsuyama, Takayuki| Katsuyama, Eri| Nasu, Yoshihisa| Sada, Ken-Ei| Wada, Jun| |
| Keywords | Nail-patella syndrome Rheumatoid arthritis Joint dislocation Iliac horn Case report |
| Note | The version of record of this article, first published in BMC Musculoskeletal Disorders, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12891-024-07242-2| |
| Published Date | 2024-02-14 |
| Publication Title | BMC Musculoskeletal Disorders |
| Volume | volume25 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 139 |
| ISSN | 1471-2474 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2024. |
| File Version | publisher |
| PubMed ID | 38355529 |
| DOI | 10.1186/s12891-024-07242-2 |
| Web of Science KeyUT | 001162669400002 |
| Related Url | isVersionOf https://doi.org/10.1186/s12891-024-07242-2 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsuji, Kenji| Nakanoh, Hiroyuki| Fukushima, Kazuhiko| Kitamura, Shinji| Wada, Jun| |
| Keywords | microRNA acute kidney injury biomarker mesenchymal stem cell |
| Published Date | 2023-09-09 |
| Publication Title | Diagnostics |
| Volume | volume13 |
| Issue | issue18 |
| Publisher | MDPI |
| Start Page | 2893 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 37761260 |
| DOI | 10.3390/diagnostics13182893 |
| Web of Science KeyUT | 001119215900001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics13182893 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sang, Yizhen| Tsuji, Kenji| Nakanoh, Hiroyuki| Fukushima, Kazuhiko| Kitamura, Shinji| Wada, Jun| |
| Keywords | semaphorin 3A neuropilin-1 podocyte diabetic nephropathy acute kidney injury chronic kidney injury lupus nephritis fibrosis apoptosis inflammation |
| Published Date | 2023-09-25 |
| Publication Title | Diagnostics |
| Volume | volume13 |
| Issue | issue19 |
| Publisher | MDPI |
| Start Page | 3038 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 37835781 |
| DOI | 10.3390/diagnostics13193038 |
| Web of Science KeyUT | 001083705600001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics13193038 |
| Title Alternative | Current findings on familial hypobetalipoproteinemia |
|---|---|
| Author | Eguchi, Jun| Wada, Jun| |
| Keywords | 低脂血症 家族性低βリポタンパク血症 無βリポタンパク血症 カイロミクロン停滞病 |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2023-08-01 |
| Volume | volume135 |
| Issue | issue2 |
| Start Page | 81 |
| End Page | 84 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.135.81 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2023 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.135.81 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsuji, Kenji| Okuyama, Yuka| Asano, Yosuke| Yamaoka, Kimitomo| Kitamura, Shinji| Wada, Jun| |
| Keywords | ANCA-associated vasculitis Sjogren's syndrome sarcoidosis monoclonal gammopathy of undetermined significance |
| Published Date | 2023-08-01 |
| Publication Title | Internal Medicine |
| Volume | volume62 |
| Issue | issue15 |
| Publisher | The Japanese Society of Internal Medicine |
| Start Page | 2215 |
| End Page | 2221 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 36450474 |
| DOI | 10.2169/internalmedicine.0966-22 |
| Web of Science KeyUT | 001045161600001 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.0966-22 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kurooka, Naoko| Eguchi, Jun| Wada, Jun| |
| Keywords | Dibaetes GPIHBP1 Lipoprotein lipase |
| Published Date | 2023-07-13 |
| Publication Title | Journal of Diabetes Investigation |
| Volume | volume14 |
| Issue | issue10 |
| Publisher | Wiley |
| Start Page | 1148 |
| End Page | 1156 |
| ISSN | 2040-1116 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Authors. |
| File Version | publisher |
| PubMed ID | 37448184 |
| DOI | 10.1111/jdi.14056 |
| Web of Science KeyUT | 001024517600001 |
| Related Url | isVersionOf https://doi.org/10.1111/jdi.14056 |
| JaLCDOI | 10.18926/AMO/65489 |
|---|---|
| FullText URL | 77_3_243.pdf |
| Author | Shibata, Yusuke| Eguchi, Jun| Wada, Jun| |
| Abstract | Brown adipose tissue (BAT) plays a critical role in metabolic homeostasis. BAT dysfunction is associated with the development of obesity through an imbalance between energy expenditure and energy intake. The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) is the master regulator of adipogenesis. However, the roles of PPARγ and thiazolidinediones (TZDs) in the regulation of BAT metabolism remain unclear. TZDs, which are selective PPARγ activators, improve systemic insulin resistance in animals and humans. In the present study, we generated brown adipocyte-specific PPARγ-deficient mice (BATγKO) to examine the in vivo roles of PPARγ and TZDs in BAT metabolism. In electron microscopic examinations, brown adipocyte-specific PPARγ deletion promoted severe whitening of brown fat and morphological alteration of mitochondria. Brown adipocyte-specific PPARγ deletion also reduced mRNA expression of BAT-selective genes. Although there was no difference in energy expenditure between control and BATγKO mice in calorimetry, norepinephrine-induced thermogenesis was impaired in BATγKO mice. Moreover, pioglitazone treatment improved diet-induced insulin resistance in the control mice but not in the BATγKO mice. These findings suggest that BAT PPARγ is necessary for the maintenance of brown adipocyte function and for the insulin-sensitizing action of TZDs. |
| Keywords | PPARγ brown adipose tissue thiazolidinediones |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 243 |
| End Page | 254 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357625 |
| Web of Science KeyUT | 001026279600002 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Onishi, Yasuhiro| Uchida, Haruhito A.| Maeshima, Yohei| Okuyama, Yuka| Otaka, Nozomu| Ujike, Haruyo| Tanaka, Keiko| Takeuchi, Hidemi| Tsuji, Kenji| Kitagawa, Masashi| Tanabe, Katsuyuki| Morinaga, Hiroshi| Kinomura, Masaru| Kitamura, Shinji| Sugiyama, Hitoshi| Ota, Kosuke| Maruyama, Keisuke| Hiramatsu, Makoto| Oshiro, Yoshiyuki| Morioka, Shigeru| Takiue, Keiichi| Omori, Kazuyoshi| Fukushima, Masaki| Gamou, Naoyuki| Hirata, Hiroshi| Sato, Ryosuke| Makino, Hirofumi| Wada, Jun| |
| Keywords | chronic kidney disease (CKD) medical cooperation patient care team OCKD-NET |
| Published Date | 2023-03-26 |
| Publication Title | Journal of Personalized Medicine |
| Volume | volume13 |
| Issue | issue4 |
| Publisher | MDPI |
| Start Page | 582 |
| ISSN | 2075-4426 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 37108968 |
| DOI | 10.3390/jpm13040582 |
| Web of Science KeyUT | 000977705500001 |
| Related Url | isVersionOf https://doi.org/10.3390/jpm13040582 |
| Title Alternative | Vitamin D-resistant rickets/osteomalacia: FGF23-related hypophosphatemic rickets/osteomalacia |
|---|---|
| Author | Fujisawa, Satoshi| Inagaki, Kenichi| Wada, Jun| |
| Keywords | FGF23 くる病 骨軟化症 低リン血症 |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2022-08-01 |
| Volume | volume134 |
| Issue | issue2 |
| Start Page | 92 |
| End Page | 94 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.134.92 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2022 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.134.92 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Asano, Yosuke| Matsumoto, Yoshinori| Wada, Jun| Rottapel, Robert| |
| Keywords | E3-ubiquitin ligases ubiquitylation proteasomal degradation osteoimmunology cherubism |
| Published Date | 2023-02-23 |
| Publication Title | Frontiers in Immunology |
| Volume | volume14 |
| Publisher | Frontiers Media |
| Start Page | 1120710 |
| ISSN | 1664-3224 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Asano, Matsumoto, Wada and Rottapel. |
| File Version | publisher |
| PubMed ID | 36911671 |
| DOI | 10.3389/fimmu.2023.1120710 |
| Web of Science KeyUT | 000945836300001 |
| Related Url | isVersionOf https://doi.org/10.3389/fimmu.2023.1120710 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tanaka, Keiko| Sugiyama, Hitoshi| Morinaga, Hiroshi| Kitagawa, Masashi| Kano, Yuzuki| Onishi, Yasuhiro| Mise, Koki| Tanabe, Katsuyuki| Uchida, Haruhito A.| Wada, Jun| |
| Keywords | IgA nephropathy cytokines sCD40L IL-31 proteinuria inflammation interstitial fibrosis |
| Published Date | 2023-03-03 |
| Publication Title | Journal of Clinical Medicine |
| Volume | volume12 |
| Issue | issue5 |
| Publisher | MDPI |
| Start Page | 2023 |
| ISSN | 2077-0383 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 36902810 |
| DOI | 10.3390/jcm12052023 |
| Web of Science KeyUT | 000947139700001 |
| Related Url | isVersionOf https://doi.org/10.3390/jcm12052023 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsuoka-Uchiyama, Natsumi| Tsuji, Kenji| Takahashi, Kensaku| Fukushima, Kazuhiko| Takeuchi, Hidemi| Kitamura, Shinji| Inagaki, Kenichi| Uchida, Haruhito A. A.| Wada, Jun| |
| Keywords | hypothyroidism kidney function urinary creatinine excretion |
| Published Date | 2023-02-10 |
| Publication Title | Diagnostics |
| Volume | volume13 |
| Issue | issue4 |
| Publisher | MDPI |
| Start Page | 669 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 36832157 |
| DOI | 10.3390/diagnostics13040669 |
| Web of Science KeyUT | 000939117200001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics13040669 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nojima, Ichiro| Wada, Jun| |
| Keywords | CD8 T cells AMPK mTORC OXPHOS autoimmune disease aging cancer |
| Published Date | 2023-01-01 |
| Publication Title | International Journal Of Molecular Sciences |
| Volume | volume24 |
| Issue | issue1 |
| Publisher | MDPI |
| Start Page | 755 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 36614197 |
| DOI | 10.3390/ijms24010755 |
| Web of Science KeyUT | 000908631300001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms24010755 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hayashi, Keigo| Sada, Ken-Ei| Asano, Yosuke| Katayama, Yu| Ohashi, Keiji| Morishita, Michiko| Miyawaki, Yoshia| Watanabe, Haruki| Katsuyama, Takayuki| Narazaki, Mariko| Matsumoto, Yoshinori| Yajima, Nobuyuki| Yoshimi, Ryusuke| Shimojima, Yasuhiro| Ohno, Shigeru| Kajiyama, Hiroshi| Ichinose, Kunihiro| Sato, Shuzo| Fujiwara, Michio| Wada, Jun| |
| Published Date | 2022-06-29 |
| Publication Title | Plos One |
| Volume | volume17 |
| Issue | issue6 |
| Publisher | Public Library Science |
| Start Page | e0270569 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Hayashi et al. |
| File Version | publisher |
| PubMed ID | 35767524 |
| DOI | 10.1371/journal.pone.0270569 |
| Web of Science KeyUT | 000892027900189 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0270569 |
