FullText URL | fulltext.pdf |
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Author | Fujimoto, Takuya| Yamasaki, Osamu| Kanehira, Noriyuki| Matsushita, Hirokazu| Sakurai, Yoshinori| Kenmotsu, Naoya| Mizuta, Ryo| Kondo, Natsuko| Takata, Takushi| Kitamatsu, Mizuki| Igawa, Kazuyo| Fujimura, Atsushi| Otani, Yoshihiro| Shirakawa, Makoto| Shigeyasu, Kunitoshi| Teraishi, Fuminori| Togashi, Yosuke| Suzuki, Minoru| Fujiwara, Toshiyoshi| Michiue, Hiroyuki| |
Keywords | abscopal effect advanced melanoma boron neutron capture therapy boron-neutron immunotherapy immune combination therapy |
Published Date | 2024-08-09 |
Publication Title | Cancer Science |
Volume | volume115 |
Issue | issue10 |
Publisher | Wiley |
Start Page | 3231 |
End Page | 3247 |
ISSN | 1347-9032 |
NCID | AA11808050 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 The Author(s). |
File Version | publisher |
PubMed ID | 39119813 |
DOI | 10.1111/cas.16298 |
Web of Science KeyUT | 001287521700001 |
Related Url | isVersionOf https://doi.org/10.1111/cas.16298 |
FullText URL | fulltext20211224-1.pdf |
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Author | Matsuo, Toshihiko| Yashiro, Masato| Yamasaki, Osamu| Tanaka, Takehiro| Manki, Akira| |
Keywords | autoinflammatory diseases Blau syndrome Muckle-Wells syndrome CINCA/NOMID syndrome cryopyrin-associated periodic syndromes optic disc swelling (optic papillitis) |
Published Date | 2021-12-19 |
Publication Title | Life |
Volume | volume11 |
Issue | issue12 |
Publisher | MDPI AG |
Start Page | 1433 |
ISSN | 2075-1729 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 by the authors. |
File Version | publisher |
DOI | 10.3390/life11121433 |
Related Url | isVersionOf https://doi.org/10.3390/life11121433 |
FullText URL | fulltext20211214-1.pdf |
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Author | Matsuo, Toshihiko| Yamasaki, Osamu| Tanaka, Takehiro| Katsui, Kuniaki| Waki, Takahiro| |
Keywords | ocular surface conjunctiva malignant melanoma proton beam therapy pembrolizumab PD‑1 inhibitor immune checkpoint inhibitor corneal perforation |
Published Date | 2021-11-18 |
Publication Title | Molecular and Clinical Oncology |
Volume | volume16 |
Issue | issue1 |
Publisher | Spandidos Publications |
Start Page | 12 |
ISSN | 2049-9450 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © Matsuo et al. |
File Version | publisher |
PubMed ID | 34881032 |
DOI | 10.3892/mco.2021.2445 |
Web of Science KeyUT | 000727359100001 |
Related Url | isVersionOf https://doi.org/10.3892/mco.2021.2445 |
FullText URL | fulltext20211206-3.pdf |
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Author | Kawashima, Shusuke| Inozume, Takashi| Kawazu, Masahito| Ueno, Toshihide| Nagasaki, Joji| Tanji, Etsuko| Honobe, Akiko| Ohnuma, Takehiro| Kawamura, Tatsuyoshi| Umeda, Yoshiyasu| Nakamura, Yasuhiro| Kawasaki, Tomonori| Kiniwa, Yukiko| Yamasaki, Osamu| Fukushima, Satoshi| Ikehara, Yuzuru| Mano, Hiroyuki| Suzuki, Yutaka| Nishikawa, Hiroyoshi| Matsue, Hiroyuki| Togashi, Yosuke| |
Published Date | 2021-11 |
Publication Title | Journal for ImmunoTherapy of Cancer |
Volume | volume9 |
Issue | issue11 |
Publisher | BMJ |
Start Page | e003134 |
ISSN | 2051-1426 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © Author(s) (or their employer(s)) 2021. |
File Version | publisher |
DOI | 10.1136/jitc-2021-003134 |
Web of Science KeyUT | 000720981900005 |
Related Url | isVersionOf https://doi.org/10.1136/jitc-2021-003134 |
FullText URL | fulltext.pdf |
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Author | Nomura, Hayato| Suganuma, Mutsumi| Takeichi, Takuya| Kono, Michihiro| Isokane, Yuki| Sunagawa, Ko| Kobashi, Mina| Sugihara, Satoru| Kajita, Ai| Miyake, Tomoko| Hirai, Yoji| Yamasaki, Osamu| Akiyama, Masashi| Morizane, Shin| |
Keywords | atopic dermatitis serine proteases kallikrein-related peptidases epidermal barrier dysfunction lympho-epithelial Kazal-type-related inhibitor (LEKTI) SPINK5 filaggrin |
Published Date | 2020-01-30 |
Publication Title | International Journal of Molecular Sciences |
Volume | volume21 |
Issue | issue3 |
Publisher | MDPI |
Start Page | 913 |
ISSN | 1422-0067 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 32019242 |
DOI | 10.3390/ijms21030913 |
Web of Science KeyUT | 000522551604010 |
Related Url | isVersionOf https://doi.org/10.3390/ijms21030913 |
FullText URL | JIMHICR2019.pdf |
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Author | Matsuo, Toshihiko| Tanaka, Takehiro| Yamasaki, Osamu| |
Keywords | BRAF inhibitor BRAF mutation MEK inhibitor PET/CT dabrafenib lacrimal sac malignant melanoma trametinib |
Note | UNSP 2324709619888052| |
Published Date | 2019-11-20 |
Publication Title | Journal of Investigative Medicine High Impact Case Reports |
Volume | volume7 |
Publisher | Sage Publications |
Start Page | 1 |
End Page | 6 |
ISSN | 2324-7096 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | publisher |
PubMed ID | 31747798 |
DOI | 10.1177/2324709619888052 |
Web of Science KeyUT | 000498954100001 |
Related Url | isVersionOf https://doi.org/10.1177/2324709619888052 |
FullText URL | JDS96_1_26.pdf Fig.pdf |
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Author | Sugihara, Satoru| Sugimoto, Saeko| Tachibana, Kota| Kobashi, Mina| Nomura, Hayato| Miyake, Tomoko| Hirai, Yoji| Yamasaki, Osamu| Morizane, Shin| |
Keywords | Epidermal keratinocyte IL-17A Lympho-epithelial Kazal-type inhibitor Serine protease inhibitor TNF-α |
Published Date | 2019-08-21 |
Publication Title | Journal of Dermatological Science |
Volume | volume96 |
Issue | issue1 |
Publisher | Elsevier |
Start Page | 26 |
End Page | 32 |
ISSN | 09231811 |
NCID | AA1075636X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 31501002 |
DOI | 10.1016/j.jdermsci.2019.08.007 |
Web of Science KeyUT | 000497889600004 |
Related Url | isVersionOf https://doi.org/10.1016/j.jdermsci.2019.08.007 |
Author | Tada, Kotaro| Hamada, Toshihisa| Asagoe, Kenji| Umemura, Hiroshi| Mizuno-Ikeda, Kazuko| Aoyama, Yumi| Otsuka, Masaki| Yamasaki, Osamu| Iwatsuki, Keiji| |
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Published Date | 2014-11 |
Publication Title | European Journal of Dermatology |
Volume | volume24 |
Issue | issue6 |
Content Type | Journal Article |
JaLCDOI | 10.18926/AMO/53118 |
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FullText URL | 69_1_17.pdf |
Author | Suzuki, Norihiro| Takata, Minoru| Shirafuji, Yoshinori| Otsuka, Masaki| Yamasaki, Osamu| Asagoe, Kenji| Hatta, Naohito| Iwatsuki, Keiji| |
Abstract | Sentinel lymph node (SLN) biopsies have widely been used for the detection of occult LN metastasis of malignant melanoma (MM). In addition to conventional biomarkers, we assessed the diagnostic and prognostic significance of melanoma-initiating cell (MIC) markers in SLNs of MM. We examined the expressions of gp100, MART-1 and tyrosinase mRNA for routine diagnosis and those of ABCB5, CD133, nestin, KDM5B, NGFR and RANK mRNA as MIC markers. The presence of micrometastasis was confirmed immunohistochemically using antibodies to S-100, HMB-45, MART-1, and tyrosinase. Discordance between immunohistochemical and molecular data was observed in 14 of 70 (20.0%) patients, among whom five (7.1%) were positive for only molecular markers;two of these five patients tested positive for micrometastasis by repeated immunohistochemical stainings. The quantitative expression levels of gp100, MART-1, and tyrosinase mRNA were significantly higher in the metastatic LNs;the cut-off values remain to be elucidated. ABCB5 mRNA expression was detected more frequently in the metastatic SLNs (p<0.05) and in the group of patients with recurrence. To make a definite diagnosis of metastasis, we still need a combination of immunohistochemical and molecular probes. ABCB5 might be a suitable molecular marker for the detection of melanoma-initiating cells in SLNs. |
Keywords | melanoma cancer-initiating cell sentinel lymph node ABCB5 |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2015-02 |
Volume | volume69 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 17 |
End Page | 27 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 25703167 |
Web of Science KeyUT | 000349740300002 |
Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/53114 |
Author | Yamasaki, Osamu| |
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Published Date | 2007-05-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume119 |
Issue | issue1 |
Content Type | Journal Article |
Author | 山﨑 修| |
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Published Date | 2002-03-25 |
Publication Title | |
Content Type | Thesis or Dissertation |