ID | 61494 |
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Author |
Nomura, Emi
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kawahara, Yuko
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Omote, Yoshio
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Tadokoro, Koh
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Takemoto, Mami
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Kaken ID
Hishikawa, Nozomi
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kaken ID
Yamashita, Toru
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Kaken ID
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Ogata, Hidenori
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University
Abe, Koji
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kaken ID
publons
researchmap
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Abstract | Combined central and peripheral demyelination (CCPD) causes demyelination in both the central and peripheral nervous systems. Anti-neurofascin 155 antibody plays an important pathogenic role in CCPD, but evidence concerning an association between this antibody and CCPD remains inconclusive. Although there have been no reports of precedent optic neuritis developing into CCPD, we herein report a Japanese man in whom optic neuritis recurred four times over nine years and who developed CCPD without positive antineurofascin 155 antibody. This case suggests the possibility of developing CCPD after optic nerve neuritis and the existence of an unknown antibody that induces CCPD.
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Keywords | Combined central and peripheral demyclination (CCPD)
recurrent optic neuritis
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Published Date | 2021-01-15
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Publication Title |
Internal Medicine
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Volume | volume60
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Issue | issue2
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Publisher | The Japanese Society of Internal Medicine
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Start Page | 305
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End Page | 308
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ISSN | 0918-2918
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Content Type |
Journal Article
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language |
English
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OAI-PMH Set |
岡山大学
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Copyright Holders | © 2021 The Japanese Society of Internal Medicine
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File Version | publisher
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.5536-20
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License | https://creativecommons.org/licenses/ by-nc-nd/4.0/
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Funder Name |
Japan Agency for Medical Research and Development
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助成番号 | 17H0419611
15K0931607
17H0975609
17K1082709
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