| FullText URL | fulltext.pdf |
|---|---|
| Author | Katayama, Norihisa| Sato, Shuhei| Katsui, Kuniaki| Takemoto, Mitsuhiro| Tsuda, Toshihide| Yoshida, Atsushi| Morito, Tsuneharu| Nakagawa, Tomio| Mizutani, Akifumi| Waki, Takahiro| Niiya, Harutaka| Kanazawa, Susumu| |
| Keywords | Breast cancer Breast-conserving surgery Radiotherapy Radiation-induced BOOP syndrome Endocrine therapy |
| Published Date | 2009-03-15 |
| Publication Title | International journal of radiation oncology, biology, physics |
| Volume | volume73 |
| Issue | issue4 |
| Publisher | Elsevier |
| Start Page | 1049 |
| End Page | 1054 |
| ISSN | 0360-3016 |
| NCID | AA00680920 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 18755559 |
| DOI | 10.1016/j.ijrobp.2008.05.050 |
| Web of Science KeyUT | 000264257400014 |
| Related Url | isVersionOf https://doi.org/10.1016/j.ijrobp.2008.05.050 |
| JaLCDOI | 10.18926/AMO/53521 |
|---|---|
| FullText URL | 69_3_145.pdf |
| Author | Ishii, Hiroko| Kamikawa, Shigeshi| Hirohata, Satoshi| Mizutani, Akifumi| Abe, Koji| Seno, Masaharu| Oohashi, Toshitaka| Ninomiya, Yoshifumi| |
| Abstract | Eosinophil cationic protein (ECP) is well known as a cationic protein contained in the basic granules of activated eosinophils. Recent studies have reported that ECP exhibits novel activities on various types of cells, including rat neonatal cardiomyocytes. Here we evaluated the effects of ECP on rat cardiac myoblast H9c2 cells. Our results showed that ECP enhanced the survival of the cells, in part by promoting the ERK and Akt/GSK-3β signaling pathways. ECP attenuated the cytotoxic effects of H2O2 on H9c2 cells as well as the production of reactive oxygen species, the number of apoptotic cells and caspase 3/7 activity in the cells. In conclusion, ECP activated the ERK and Akt/GSK-3β pathways, resulting in anti-oxidative effects on H9c2 cells that attenuated apoptosis. |
| Keywords | ECP reactive oxygen species Akt ERK |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-06 |
| Volume | volume69 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 145 |
| End Page | 153 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26101190 |
| Web of Science KeyUT | 000356903000003 |
| FullText URL | PLOSONE_9_9_e107976.pdf |
|---|---|
| Author | Shigehiro, Tsukasa| Kasai, Tomonari| Murakami, Masaharu| Sekhar, Sreeja C.| Tominaga, Yuki| Okada, Masashi| Kudoh, Takayuki| Mizutani, Akifumi| Murakami, Hiroshi| Salomon, David S.| Mikuni, Katsuhiko| Mandai, Tadakatsu| Hamada, Hiroki| Seno, Masaharu| |
| Published Date | 2014-09-29 |
| Publication Title | PLoS ONE |
| Volume | volume9 |
| Issue | issue9 |
| Publisher | Public Library Science |
| Start Page | e107976 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| PubMed ID | 25264848 |
| DOI | 10.1371/journal.pone.0107976 |
| Web of Science KeyUT | 000345745400036 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0107976 |
| FullText URL | PLoSONE_7_4_e33544.pdf |
|---|---|
| Author | Chen, Ling| Kasai, Tomonari| Li, Yueguang| Sugii, Yuh| Jin, Guoliang| Okada, Masashi| Vaidyanath, Arun| Mizutani, Akifumi| Satoh, Ayano| Kudoh, Takayuki| Hendrix, Mary J. C.| Salomon, David S| Fu, Li| Seno, Masaharu| |
| Published Date | 2012-04-12 |
| Publication Title | PLoS ONE |
| Volume | volume7 |
| Issue | issue4 |
| Publisher | PUBLIC LIBRARY SCIENCE |
| Start Page | e33544 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| PubMed ID | 22511923 |
| DOI | 10.1371/journal.pone.0033544 |
| Web of Science KeyUT | 000305338600009 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0033544 |
