| ID | 15095 |
| JaLCDOI | |
| Sort Key | 18
|
| Title Alternative | Mechanisms of pancreatic fibrosis
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| FullText URL | |
| Author |
Ochi, Koji
Chowdhury, Riaz
Ichimura, Mitsuko
Matsumura, Naoki
Tanaka, Juntaro
Mizushima, Takaaki
Kaken ID
researchmap
Yamamoto, Ryoichi
Harada, Hideo
Yokota, Satoshi
Hosaki, Yasuhiro
Tanizaki, Yoshiro
|
| Abstract | 膵の線維化は慢性膵炎に特徴的な病理組織所見の一つであるが,その発生機序については不明な点か多い｡慢性膵炎はいったん発症すれば,進行性かつ非可逆性であるとされるが,その非可逆性に膵の線維化が関与するとされる｡膵の線維化の発生機序を明らかにし,線維化に対する根本的な治療法の確立が望まれるところである｡そこで,本稿では今後の膵の線維化の研究課題を明らかにする目的で,現在までの膵臓線維化の発生機序に関する知見を整理した｡
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| 抄録（別言語） | Pancreatic fibrosis is an outstanding morphological
feature in chronic pancreatis although it is seen in pancreatic cancer and convalescent stage of acute pancreatitis. Progressive fibrosis in chronic pancreatitis leads to the destruction and contributes to irreversiblity
of chronic pancreatitis. Exact mechanisms of pancreatic fibrosis is not yet unclear, although advances in molecular biology have revealed possible roles of cytokines and growth factors in it. We summarized our
understanding of pancreatic fibrosis in the revIew.
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| Keywords | 膵臓 (pancreas)
線維化 (fibrosis)
サイトカイン (cytokine)
慢性膵炎 (chronic pancreatitis)
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| Publication Title |
岡大三朝分院研究報告
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| Published Date | 1996-11
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| Volume | volume67
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| Publisher | 岡山大学医学部附属病院三朝分院
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| Publisher Alternative | Misasa Medical Branch, Okayama University Medical School
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| Start Page | 115
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| End Page | 120
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| ISSN | 0918-7839
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| NCID | AN10430852
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| Content Type |
Departmental Bulletin Paper
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| OAI-PMH Set |
岡山大学
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| language |
Japanese
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| File Version | publisher
|
| NAID | |
| Eprints Journal Name | mmc
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