| FullText URL | fulltext.pdf suppl.pdf |
|---|---|
| Author | Im, Dohyun| Jormakka, Mika| Juge, Narinobu| Kishikawa, Jun-ichi| Kato, Takayuki| Sugita, Yukihiko| Noda, Takeshi| Uemura, Tomoko| Shiimura, Yuki| Miyaji, Takaaki| Asada, Hidetsugu| Iwata, So| |
| Published Date | 2024-09-16 |
| Publication Title | Nature Communications |
| Volume | volume15 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 7661 |
| ISSN | 2041-1723 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2024 |
| File Version | publisher |
| PubMed ID | 39284862 |
| DOI | 10.1038/s41467-024-51960-z |
| Web of Science KeyUT | 001314910500039 |
| Related Url | isVersionOf https://doi.org/10.1038/s41467-024-51960-z |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nishii, Naoko| Kawai, Tomoko| Yasuoka, Hiroki| Abe, Tadashi| Tatsumi, Nanami| Harada, Yuika| Miyaji, Takaaki| Li, Shunai| Tsukano, Moemi| Watanabe, Masami| Ogawa, Daisuke| Wada, Jun| Takei, Kohji| Yamada, Hiroshi| |
| Keywords | VGLUT3 glutamate podocyte glutamatergic transmission |
| Published Date | 2025-03-11 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume26 |
| Issue | issue6 |
| Publisher | MDPI |
| Start Page | 2485 |
| ISSN | 1661-6596 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 by the authors. |
| File Version | publisher |
| PubMed ID | 40141129 |
| DOI | 10.3390/ijms26062485 |
| Web of Science KeyUT | 001452693900001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms26062485 |
| JaLCDOI | 10.18926/AMO/67663 |
|---|---|
| FullText URL | 78_5_387.pdf |
| Author | Naoe, Shota| Tanaka, Ayumi| Kanzaki, Norie| Takenaka, Reiju| Sakoda, Akihiro| Miyaji, Takaaki| Yamaoka, Kiyonori| Kataoka, Takahiro| |
| Abstract | Radon is a known risk factor for lung cancer; however, it can be used beneficially, such as in radon therapy. We have previously reported the enhancement of antioxidant effects associated with trace amounts of oxidative stress as one of the positive biological effects of radon inhalation. However, the biological effects of radon inhalation are incompletely understood, and more detailed and comprehensive studies are required. Although several studies have used proteomics to investigate the effects of radon inhalation on body proteins, none has focused on brain proteins. In this study, we evaluated the expression status of proteins in murine brains using proteomic and multivariate analyses to identify those whose expressions changed following two days of radon inhalation at a concentration of 1,500 Bq/m3. We found associations of radon inhalation with the expressions of seven proteins related to neurotransmission and heat shock. These proteins may be proposed as biomarkers indicative of radon inhalation. Although further studies are required to obtain the detailed biological significance of these protein alterations, this study contributes to the elucidation of the biological effects of radon inhalation as a low-dose radiation. |
| Keywords | radon inhalation proteomics multivariate analysis brain oxidative stress |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-10 |
| Volume | volume78 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 387 |
| End Page | 399 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39467657 |
| Web of Science KeyUT | 001343346400005 |
| Author | Miyaji, Takaaki| Kuromori, Takashi| Takeuchi, Yu| Yamaji, Naoki| Yokosho, Kengo| Shimazawa, Atsushi| Sugimoto, Eriko| Omote, Hiroshi| Ma, Jian Feng| Shinozaki, Kazuo| Moriyama, Yoshinori| |
|---|---|
| Published Date | 2015-01-05 |
| Publication Title | Nature Communications |
| Volume | volume6 |
| Content Type | Journal Article |
| Author | Hiasa, Miki| Miyaji, Takaaki| Haruna, Yuka| Takeuchi, Tomoya| Harada, Yuika| Moriyama, Sawako| Yamamoto, Akitsugu| Omote, Hiroshi| Moriyama, Yoshinori| |
|---|---|
| Published Date | 2014-10-30 |
| Publication Title | Scientific Reports |
| Volume | volume4 |
| Content Type | Journal Article |
| Author | Sawada, Keisuke| Echigo, Noriko| Juge, Narinobu| Miyaji, Takaaki| Otsuka, Masato| Omote, Hiroshi| Yamamoto, Akitsugu| Moriyama, Yoshinori| |
|---|---|
| Published Date | 2008-04-01 |
| Publication Title | Proceedings of the National Academy of Sciences of the United States of America |
| Volume | volume105 |
| Issue | issue15 |
| Content Type | Journal Article |
| Author | Miyaji, Takaaki| |
|---|---|
| Published Date | 2009-03-25 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
