Nakatsuka, Atsuko - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

GRP78 Contributes to the Beneficial Effects of SGLT2 Inhibitor on Proximal Tubular Cells in DKD

FullText URL	fulltext20240924-02.pdf fig20240924-02.pdf suppl_information20240924-02.pdf suppl_fig20240924-02.pdf
Author	Nakatsuka, Atsuko\| Yamaguchi, Satoshi\| Wada, Jun\|
Note	This is an Accepted Manuscript of an article published by American Diabetes Association.\|
Published Date	2024-02-23
Publication Title	Diabetes
Volume	volume73
Issue	issue5
Publisher	American Diabetes Association
Start Page	763
End Page	779
ISSN	0012-1797
NCID	AA00628057
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the American Diabetes Association.
File Version	author
PubMed ID	38394641
DOI	10.2337/db23-0581
Web of Science KeyUT	001288274500014
Related Url	isVersionOf https://doi.org/10.2337/db23-0581

Plasma angiotensin-converting enzyme 2 (ACE2) is a marker for renal outcome of diabetic kidney disease (DKD) (U-CARE study 3)

FullText URL	fulltext.pdf
Author	Ueno, Asami\| Onishi, Yasuhiro\| Mise, Koki\| Yamaguchi, Satoshi\| Kanno, Ayaka\| Nojima, Ichiro\| Higuchi, Chigusa\| Uchida, Haruhito A.\| Shikata, Kenichi\| Miyamoto, Satoshi\| Nakatsuka, Atsuko\| Eguchi, Jun\| Hida, Kazuyuki\| Katayama, Akihiro\| Watanabe, Mayu\| Nakato, Tatsuaki\| Tone, Atsuhito\| Teshigawara, Sanae\| Matsuoka, Takashi\| Kamei, Shinji\| Murakami, Kazutoshi\| Shimizu, Ikki\| Miyashita, Katsuhito\| Ando, Shinichiro\| Nunoue, Tomokazu\| Wada, Jun\|
Published Date	2024-05
Publication Title	BMJ Open Diabetes Research and Care
Volume	volume12
Issue	issue3
Publisher	BMJ Publishing Group
Start Page	e004237
ISSN	2052-4897
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Author(s) (or their employer(s)) 2024.
File Version	publisher
PubMed ID	38816205
DOI	10.1136/bmjdrc-2024-004237
Web of Science KeyUT	001236385500001
Related Url	isVersionOf https://doi.org/10.1136/bmjdrc-2024-004237

Inhibition of Amino Acids Influx into Proximal Tubular Cells Improves Lysosome Function in Diabetes

FullText URL	fulltext.pdf
Author	Kano, Yuzuki\| Yamaguchi, Satoshi\| Mise, Koki\| Kawakita, Chieko\| Onishi, Yasuhiro\| Kurooka, Naoko\| Sugawara, Ryosuke\| Albuayjan, Haya Hamed Hassan\| Nakatsuka, Atsuko\| Eguchi, Jun\| Wada, Jun\|
Keywords	diabetes mellitus diabetic nephropathy metabolism obesity tubular epithelium
Published Date	2023-12-08
Publication Title	Kidney360
Volume	volume5
Issue	issue2
Publisher	Ovid Technologies (Wolters Kluwer Health)
Start Page	182
End Page	194
ISSN	2641-7650
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	Copyright © 2023 The Author(s).
File Version	publisher
PubMed ID	38062578
DOI	10.34067/kid.0000000000000333
Web of Science KeyUT	001178403800002
Related Url	isVersionOf https://doi.org/10.34067/kid.0000000000000333

Adipocyte-Specific Inhibition of Mir221/222 Ameliorates Diet-Induced Obesity Through Targeting Ddit4

FullText URL	fulltext.pdf
Author	Yamaguchi, Satoshi\| Zhang, Dongxiao\| Katayama, Akihiro\| Kurooka, Naoko\| Sugawara, Ryosuke\| Albuayjan, Haya Hamed Hassan\| Nakatsuka, Atsuko\| Eguchi, Jun\| Wada, Jun\|
Keywords	non-coding RNAs microRNA adipose tissues Adipogenesis mTORC1
Published Date	2022-01-03
Publication Title	Frontiers In Endocrinology
Volume	volume12
Publisher	Frontiers Media SA
Start Page	750261
ISSN	1664-2392
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 Yamaguchi, Zhang, Katayama, Kurooka, Sugawara, Albuayjan, Nakatsuka, Eguchi and Wada.
File Version	publisher
PubMed ID	35046889
DOI	10.3389/fendo.2021.750261
Web of Science KeyUT	000745695800001
Related Url	isVersionOf https://doi.org/10.3389/fendo.2021.750261

Novel Urinary Glycan Biomarkers Predict Cardiovascular Events in Patients With Type 2 Diabetes: A Multicenter Prospective Study With 5-Year Follow Up (U-CARE Study 2)

FullText URL	fulltext.pdf
Author	Mise, Koki\| Imamura, Mariko\| Yamaguchi, Satoshi\| Watanabe, Mayu\| Higuchi, Chigusa\| Katayama, Akihiro\| Miyamoto, Satoshi\| Uchida, Haruhito A.\| Nakatsuka, Atsuko\| Eguchi, Jun\| Hida, Kazuyuki\| Nakato, Tatsuaki\| Tone, Atsuhito\| Teshigawara, Sanae\| Matsuoka, Takashi\| Kamei, Shinji\| Murakami, Kazutoshi\| Shimizu, Ikki\| Miyashita, Katsuhiro\| Ando, Shinichiro\| Nunoue, Tomokazu\| Yoshida, Michihiro\| Yamada, Masao\| Shikata, Kenichi\| Wada, Jun\|
Keywords	cardiovascular event diabetes lectins N-glycans urinary biomarkers
Published Date	2021-05-24
Publication Title	Frontiers In Cardiovascular Medicine
Volume	volume8
Publisher	Frontiers Media SA
Start Page	668059
ISSN	2297-055X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
PubMed ID	34109226
NAID	120007053373
DOI	10.3389/fcvm.2021.668059
Web of Science KeyUT	000658156400001
Related Url	isVersionOf https://doi.org/10.3389/fcvm.2021.668059

Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2

FullText URL	fulltext.pdf
Author	Nunoue, Tomokazu\| Yamaguchi, Satoshi\| Teshigawara, Sanae\| Katayama, Akihiro\| Nakatsuka, Atsuko\| Eguchi, Jun\| Niki, Toshiro\| Wada, Jun\|
Published Date	2021-03-16
Publication Title	Scientific Reports
Volume	volume11
Issue	issue1
Publisher	Nature
Start Page	5991
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2021
File Version	publisher
PubMed ID	33727589
NAID	120007004155
DOI	10.1038/s41598-021-85080-1
Web of Science KeyUT	000630512100015
Related Url	isVersionOf https://doi.org/10.1038/s41598-021-85080-1

A Vaspin-HSPA1L complex protects proximal tubular cells from organelle stress in diabetic kidney disease

FullText URL	fulltext.pdf
Author	Nakatsuka, Atsuko\| Yamaguchi, Satoshi\| Eguchi, Jun\| Kakuta, Shigeru\| Iwakura, Yoichiro\| Sugiyama, Hitoshi\| Wada, Jun\|
Published Date	2021-03-19
Publication Title	Communications Biology
Volume	volume4
Issue	issue1
Publisher	Nature
Start Page	373
ISSN	2399-3642
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2021
File Version	publisher
PubMed ID	33742129
NAID	120007004153
DOI	10.1038/s42003-021-01902-y
Web of Science KeyUT	000631555700003
Related Url	isVersionOf https://doi.org/10.1038/s42003-021-01902-y

Dysfunction of CD8+PD-1+T cells in type 2 diabetes caused by the impairment of metabolism-immune axis

FullText URL	fulltext.pdf
Author	Nojima, Ichiro\| Eikawa, Shingo\| Tomonobu, Nahoko\| Hada, Yoshiko\| Kajitani, Nobuo\| Teshigawara, Sanae\| Miyamoto, Satoshi\| Tone, Atsuhito\| Uchida, Haruhito A.\| Nakatsuka, Atsuko\| Eguchi, Jun\| Shikata, Kenichi\| Udono, Heiichiro\| Wada, Jun\|
Keywords	Cytokines Diabetes Endocrine system and metabolic diseases Immunology Tumour immunology
Published Date	2020-09-10
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature Research
Start Page	14928
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	32913271
DOI	10.1038/s41598-020-71946-3
Web of Science KeyUT	000571915100049
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-71946-3

The hypoglycemia-prevention effect of sensor-augmented pump therapy with predictive low glucose management in Japanese patients with type 1 diabetes mellitus: a short-term study

FullText URL	fulltext.pdf
Author	Katayama, Akihiro\| Tone, Atsuhito\| Watanabe, Mayu\| Teshigawara, Sanae\| Miyamoto, Satoshi\| Eguchi, Jun\| Nakatsuka, Atsuko\| Shikata, Kenichi\| Wada, Jun\|
Keywords	Hypoglycemia Predictive low glucose management (PLGM) Type 1 diabetes mellitus (T1DM) Sensor-augmented pump therapy (SAP)
Note	This is a post-peer-review, pre-copyedit version of an article published in Diabetology International. The final authenticated version is available online at: http://dx.doi.org/10.1007/s13340-019-00408-7.\|
Published Date	2019-09-16
Publication Title	Diabetology International
Volume	volume11
Issue	issue2
Publisher	Springer
Start Page	97
End Page	104
ISSN	2190-1678
NCID	AA12503387
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	32206479
NAID	40022198977
DOI	10.1007/s13340-019-00408-7
Web of Science KeyUT	000520711100004
Related Url	isVersionOf https://doi.org/10.1007/s13340-019-00408-7

Mitochondrial Dynamics and Mitochondrial Dysfunction in Diabetes

JaLCDOI	10.18926/AMO/54413
FullText URL	70_3_151.pdf
Author	Wada, Jun\| Nakatsuka, Atsuko\|
Abstract	The mitochondria are involved in active and dynamic processes, such as mitochondrial biogenesis, fission, fusion and mitophagy to maintain mitochondrial and cellular functions. In obesity and type 2 diabetes, impaired oxidation, reduced mitochondrial contents, lowered rates of oxidative phosphorylation and excessive reactive oxygen species (ROS) production have been reported. Mitochondrial biogenesis is regulated by various transcription factors such as peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α), peroxisome proliferator-activated receptors (PPARs), estrogen-related receptors (ERRs), and nuclear respiratory factors (NRFs). Mitochondrial fusion is promoted by mitofusin 1 (MFN1), mitofusin 2 (MFN2) and optic atrophy 1 (OPA1), while fission is governed by the recruitment of dynamin-related protein 1 (DRP1) by adaptor proteins such as mitochondrial fission factor (MFF), mitochondrial dynamics proteins of 49 and 51 kDa (MiD49 and MiD51), and fission 1 (FIS1). Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1) and PARKIN promote DRP1-dependent mitochondrial fission, and the outer mitochondrial adaptor MiD51 is required in DRP1 recruitment and PARKIN-dependent mitophagy. This review describes the molecular mechanism of mitochondrial dynamics, its abnormality in diabetes and obesity, and pharmaceuticals targeting mitochondrial biogenesis, fission, fusion and mitophagy.
Keywords	fusion fission oxidative stress mitochondria diabetes
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2016-06
Volume	volume70
Issue	issue3
Publisher	Okayama University Medical School
Start Page	151
End Page	158
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2016 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	27339203
Web of Science KeyUT	000379406100001

Pemt deficiency ameliorates endoplasmic reticulum stress in diabetic nephropathy

Author	Watanabe, Mayu\| Nakatsuka, Atsuko\| Murakami, Kazutoshi\| Inoue, Kentaro\| Terami, Takahiro\| Higuchi, Chigusa\| Katayama, Akihiro\| Teshigawara, Sanae\| Eguchi, Jun\| Ogawa, Daisuke\| Watanabe, Eijiro\| Wada, Jun\| Makino, Hirofumi\|
Published Date	2014-05-25
Publication Title	PLOS ONE
Volume	volume9
Issue	issue3
Content Type	Journal Article

Nuclear Hormone Receptor Expression in Mouse Kidney and Renal Cell Lines

Author	Ogawa, Daisuke\| Eguchi, Jun\| Wada, Jun\| Terami, Naoto\| Hatanaka, Takashi\| Tachibana, Hiromi\| Nakatsuka, Atsuko\| Sato Horiguchi, Chikage\| Nishii, Naoko\| Makino, Hirofumi\|
Published Date	2014-01-22
Publication Title	PLOS ONE
Volume	volume9
Issue	issue1
Content Type	Journal Article

Insufficiency of phosphatidylethanolamine N-methyltransferase is risk for lean non-alcoholic steatohepatitis

Author	Nakatsuka, Atsuko\| Matsuyama, Makoto\| Yamaguchi, Satoshi\| Katayama, Akihiro\| Eguchi, Jun\| Murakami, Kazutoshi\| Teshigawara, Sanae\| Ogawa, Daisuke\| Wada, Nozomu\| Yasunaka, Tetsuya\| Ikeda, Fusao\| Takaki, Akinobu\| Watanabe, Eijiro\| Wada, Jun\|
Published Date	2016-02-17
Publication Title	Scientific Reports
Volume	volume6
Content Type	Journal Article

Beneficial impact of Gpnmb and its significance as a biomarker in nonalcoholic steatohepatitis

Author	Katayama, Akihiro\| Nakatsuka, Atsuko\| Eguchi, Jun\| Murakami, Kazutoshi\| Teshigawara, Sanae\| Kanzaki, Motoko\| Nunoue, Tomokazu\| Hida, Kazuyuki\| Wada, Nozomu\| Yasunaka, Tetsuya\| Ikeda, Fusao\| Takaki, Akinobu\| Yamamoto, Kazuhide\| Kiyonari, Hiroshi\| Makino, Hirofumi\| Wada, Jun\|
Published Date	2015
Publication Title	Scientific reports
Volume	volume5
Content Type	Journal Article

Urinary angiotensinogen is a marker for tubular injuries in patients with type 2 diabetes

Author	Terami, Takahiro\| Wada, Jun\| Inoue, Kentaro\| Nakatsuka, Atsuko\| Ogawa, Daisuke\| Teshigawara, Sanae\| Murakami, Kazutoshi\| Katayama, Akihiro\| Eguchi, Jun\| Makino, Hirofumi\|
Published Date	2013-10-22
Publication Title	International Journal of Nephrology and Renovascular Disease
Volume	volume6
Content Type	Journal Article

Urinary Fetuin-A Is a Novel Marker for Diabetic Nephropathy in Type 2 Diabetes Identified by Lectin Microarray

Author	Inoue, Kentaro\| Wada, Jun\| Eguchi, Jun\| Nakatsuka, Atsuko\| Teshigawara, Sanae\| Murakami, Kazutoshi\| Ogawa, Daisuke\| Terami, Takahiro\| Katayama, Akihiro\| Tone, Atsuhito\| Iseda, Izumi\| Hida, Kazuyuki\| Yamada, Masao\| Ogawa, Tomohisa\| Makino, Hirofumi\|
Published Date	2013-10-15
Publication Title	PLoS ONE
Volume	volume8
Issue	issue10
Content Type	Journal Article

平成25年度岡山医学会賞胸部・循環研究奨励賞（砂田賞）

Title Alternative	The 2013 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2013 Sunada Prize)
FullText URL	126_95.pdf
Author	Nakatsuka, Atsuko\|
Publication Title	岡山医学会雑誌
Published Date	2014-08-01
Volume	volume126
Issue	issue2
Start Page	95
End Page	98
ISSN	0030-1558
Related Url	http://www.okayama-u.ac.jp/user/oma/
language	Japanese
Copyright Holders	Copyright (c) 2014 岡山医学会
File Version	publisher
DOI	10.4044/joma.126.95
NAID	130004685276

Serum galectin-9 levels are elevated in the patients with type 2 diabetes and chronic kidney disease

Author	Kurose, Yuko\| Wada, Jun\| Kanzaki, Motoko\| Teshigawara, Sanae\| Nakatsuka, Atsuko\| Murakami, Kazutoshi\| Inoue, Kentaro\| Terami, Takahiro\| Katayama, Akihiro\| Watanabe, Mayu\| Higuchi, Chigusa\| Eguchi, Jun\| Miyatake, Nobuyuki\| Makino, Hirofumi\|
Published Date	2013-01-22
Publication Title	BMC Nephrology
Volume	volume14
Content Type	Journal Article

The serum vaspin levels are reduced in Japanese chronic hemodialysis patients

Author	Inoue, Junko\| Wada, Jun\| Teshigawara, Sanae\| Hida, Kazuyuki\| Nakatsuka, Atsuko\| Takatori, Yuji\| Kojo, Shoichirou\| Akagi, Shigeru\| Nakao, Kazushi\| Miyatake, Nobuyuki\| McDonald, John F.\| Makino, Hirofumi\|
Published Date	2012-12-03
Publication Title	BMC Nephrology
Volume	volume13
Content Type	Journal Article

Cell Cycle Abnormality in Metabolic Syndrome and Nuclear Receptors as an Emerging Therapeutic Target

JaLCDOI	10.18926/AMO/50405
FullText URL	67_3_129.pdf
Author	Nakatsuka, Atsuko\| Wada, Jun\| Makino, Hirofumi\|
Abstract	In recent years, many researchers have emphasized the importance of metabolic syndrome based on its increasing prevalence and its adverse prognosis due to associated chronic vascular complications. Upstream of a cluster of metabolic and vascular disorders is the accumulation of visceral adipose tissue, which plays a central role in the pathophysiology. In the accumulation of adipose tissues, cell cycle regulation is tightly linked to cellular processes such as proliferation, hypertrophy and apoptosis. In addition, various cell cycle abnormalities have also been observed in other tissues, such as kidneys and the cardiovascular system, and they are critically involved in the progression of disease. Here, we discuss cell cycle abnormalities in metabolic syndrome in various tissues. Furthermore, we describe the role of nuclear receptors in cell growth and survival, and glucose and lipid metabolism in the whole body. Therapeutic strategies for modulating various cell cycles in metabolic disorders by targeting nuclear receptors may overcome obesity and its chronic vascular complications in the future.
Keywords	nuclear receptor cell cycle metabolic syndrome diabetic nephropathy
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2013-06
Volume	volume67
Issue	issue3
Publisher	Okayama University Medical School
Start Page	129
End Page	134
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2013 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	23804135
Web of Science KeyUT	000320747900001