ID | 61873 |
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Author |
Satomi, Takuya
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
Kawano, Seiji
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
Inaba, Tomoki
Department of Gastroenterology, Kagawa Prefectural Central Hospital
Nakagawa, Masahiro
Department of Endoscopy, Hiroshima City Hiroshima Citizens Hospital
Mouri, Hirokazu
Department of Gastroenterology and Hepatology, Kurashiki Central Hospital
Yoshioka, Masao
Department of Gastroenterology and Hepatology, Okayama Saiseikai General Hospital
Tanaka, Shoichi
Department of Gastroenterology, National Hospital Organization Iwakuni Clinical Center
Toyokawa, Tatsuya
Department of Gastroenterology, National Hospital Organization Fukuyama Medical Center
Kobayashi, Sayo
Department of Internal Medicine, Fukuyama City Hospital
Tanaka, Takehiro
Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
ORCID
Kaken ID
publons
Kanzaki, Hiromitsu
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
publons
researchmap
Iwamuro, Masaya
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
ORCID
Kaken ID
publons
researchmap
Kawahara, Yoshiro
Department of Practical Gastrointestinal Endoscopy, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Okada, Hiroyuki
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kaken ID
publons
researchmap
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Abstract | BACKGROUND Recent improvements in the prognosis of patients with esophageal cancer have led to the increased occurrence of gastric tube cancer (GTC) in the reconstructed gastric tube. However, there are few reports on the treatment results of endoscopic submucosal dissection (ESD) for GTC. AIM To evaluate the efficacy and safety of ESD for GTC after esophagectomy in a multicenter trial. METHODS We retrospectively investigated 48 GTC lesions in 38 consecutive patients with GTC in the reconstructed gastric tube after esophagectomy who had undergone ESD between January 2005 and December 2019 at 8 institutions participating in the Okayama Gut Study group. The clinical indications of ESD for early gastric cancer were similarly applied for GTC after esophagectomy. ESD specimens were evaluated in 2-mm slices according to the Japanese Classification of Gastric Carcinoma with curability assessments divided into curative and non-curative resection based on the Gastric Cancer Treatment Guidelines. Patient characteristics, treatment results, clinical course, and treatment outcomes were analyzed. RESULTS The median age of patients was 71.5 years (range, 57-84years), and there were 34 men and 4 women. The median observation period after ESD was 884 d (range, 8-4040 d). The median procedure time was 81 min (range, 29-334 min), the en bloc resection rate was 91.7% (44/48), and the curative resection rate was 79% (38/48). Complications during ESD were seen in 4% (2/48) of case, and those after ESD were seen in 10% (5/48) of case. The survival rate at 5 years was 59.5%. During the observation period after ESD, 10 patients died of other diseases. Although there were differences in the procedure time between institutions, a multivariate analysis showed that tumor size was the only factor associated with prolonged procedure time. CONCLUSION ESD for GTC after esophagectomy was shown to be safe and effective.
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Keywords | Endoscopic submucosal dissection
Gastric tube
Gastric cancer
Eso-phagectomy
Multicenter study
Retrospective study
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Published Date | 2021-03-21
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Publication Title |
World Journal of Gastroenterology
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Volume | volume27
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Issue | issue11
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Publisher | Baishideng Publishing Group Inc.
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Start Page | 1043
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End Page | 1054
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ISSN | 1007-9327
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Content Type |
Journal Article
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language |
English
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OAI-PMH Set |
岡山大学
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File Version | publisher
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Related Url | isVersionOf https://doi.org/10.3748/wjg.v27.i11.1043
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License | http://creativecommons.org/Licenses/by-nc/4.0/
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