| Author | Kikuchi, Satoru| Kishimoto, Hiroyuki| Tazawa, Hiroshi| Hashimoto, Yuuri| Kuroda, Shinji| Nishizaki, Masahiko| Nagasaka, Takeshi| Shirakawa, Yasuhiro| Kagawa, Shunsuke| Urata, Yasuo| Robert M Hoffman| Fujiwara, Toshiyoshi| |
|---|---|
| Published Date | 2014-12-19 |
| Publication Title | Molecular Therapy |
| Content Type | Journal Article |
| Author | Yamada, Eiji| Shirakawa, Yasuhiro| Yamatsuji, Tomoki| Sakuma, Leon| Takaoka, Munenori| Yamada, Takako| Noma, Kazuhiro| Sakurama, Kazufumi| Fujiwara, Yasuhiro| Tanabe, Shunsuke| Nagasaka, Takeshi| Fujiwara, Toshiyoshi| Naomoto, Yoshio| |
|---|---|
| Published Date | 2012-12 |
| Publication Title | Journal of Surgical Research |
| Volume | volume178 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Yano, Shuya| Tazawa, Hiroshi| Hashimoto, Yuuri| Shirakawa, Yasuhiro| Kuroda, Shinji| Nishizaki, Masahiko| Kishimoto, Hiroyuki| Uno, Futoshi| Nagasaka, Takeshi| Urata, Yasuo| Kagawa, Shunsuke| Hoffman, Robert M.| Fujiwara, Toshiyoshi| |
|---|---|
| Published Date | 2013-12-01 |
| Publication Title | Clinical Cancer Research |
| Volume | volume19 |
| Issue | issue23 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/52407 |
|---|---|
| FullText URL | 68_2_111.pdf |
| Author | Shirakawa, Yasuhiro| Noma, Kazuhiro| Maeda, Naoaki| Katsube, Ryoichi| Tanabe, Shunsuke| Ohara, Toshiaki| Sakurama, Kazufumi| Fujiwara, Toshiyoshi| |
| Abstract | Thoracoscopic esophagectomy in the prone position (TEPP) might enable solo-surgery in cases requiring resection of the esophagus and the surrounding lymph nodes due to the associated advantages of good exposure of the surgical field and ergonomic considerations for the surgeon. However, no one approach can be for all patients requiring extensive lymphadenectomy. We recently developed an assistant-based procedure to standardize exposure of the surgical field. Patients were divided into 1 of 2 groups:a pre-standardization group (n＝37) and a post-standardization group (n＝28). The thoracoscopic operative time was significantly shorter (p＝0.0037) in the post-standardization group (n＝28; 267±31min) than in the pre-standardization group (n＝37;301±53min). Further, learning curve analysis using the moving average method showed stabilization of the thoracoscopic operative time after the standardization. No significant differences were found in the number of mediastinal lymph nodes dissected or intraoperative blood loss between the 2 groups. There were also no significant differences in the complication rate. Assistant-based surgery and standardization of the procedure resulted in a well-exposed and safe surgical field. TEPP decreased the operative time, even in patients requiring extensive lymphadenectomy. |
| Keywords | thoracoscopic esophagectomy prone position standardization |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-04 |
| Volume | volume68 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 111 |
| End Page | 117 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24743786 |
| Web of Science KeyUT | 000334652700006 |
| Author | Fujiwara, Y.| Yamada, T.| Naomoto, Y.| Yamatsuji, T.| Shirakawa, Y.| Tanabe, S.| Noma, K.| Kimura, T.| Aoki, H.| Matsukawa, H.| Kimura, M.| Nonaka, Y.| Sasaki, H.| Onoda, T.| Otawa, Y.| Takaoka, M.| Fukazawa, T.| Ohno, Y.| Fujiwara, T.| |
|---|---|
| Published Date | 2013-12 |
| Publication Title | Journal of Hospital Infection |
| Volume | volume85 |
| Issue | issue4 |
| Content Type | Journal Article |
| Title Alternative | A patient with primary malignant melanoma of the esophagus who underwent esophagectomy |
|---|---|
| FullText URL | 126_45.pdf |
| Author | Maeda, Naoaki| Shirakawa, Yasuhiro| Koujima, Takeshi| Ohara, Toshiaki| Tanabe, Shunsuke| Noma, Kazuhiro| Sakurama, Kazuhumi| Fujiwara, Toshiyosi| |
| Abstract | We report the case of a 61-old-man with a primary malignant melanoma of the esophagus, an extremely rare and highly aggressive malignancy. He presented with dysphagia, and we performed an upper gastrointestinal endoscopy that detected a tumor in the thoracic part of the esophagus. The biopsy showed malignant melanoma. PET/CT, endoscopy and an esophagogram showed that a 70-mm scaled type 2+1 tumor in the thoracic esophagus and no metastases. We diagnosed a cT3cN0cM0 cStage II tumor. We then performed a subtotal esophagectomy with two-field lymph node dissection and esophagogastrostomy via a retrosternal route. The pathological examination of the resected specimens confirmed that the type 2+1 tumor was PMME (pT2N0M0 pStage II). We administered six courses of postoperative adjuvant chemotherapy with dacarbazine, and the patient has had no recurrence for 17 months after the surgery. |
| Keywords | 食道（esophagus） 悪性黒色腫（malignant melanoma） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-04-01 |
| Volume | volume126 |
| Issue | issue1 |
| Start Page | 45 |
| End Page | 48 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.45 |
| NAID | 130004505808 |
| Title Alternative | Complete response of primary esophageal endocrine cell carcinoma resected after neoadjuvant chemotherapy with docetaxel/cisplatin/5-fluorouracil |
|---|---|
| FullText URL | 126_39.pdf |
| Author | Maeda, Naoaki| Shirakawa, Yasuhiro| Koujima, Takeshi| Ohara, Toshiaki| Tanabe, Shunsuke| Noma, Kazuhiro| Sakurama, Kazuhumi| Fujiwara, Toshiyosi| |
| Abstract | Esophageal endocrine cell carcinoma is extremely rare. We report a case of esophageal endocrine cell carcinoma showing histological complete response to neoadjuvant chemotherapy with docetaxel/cisplatin/5-fluorouracil (DCF). A 66-year-old man had been experiencing epigastralgia, and a type 2 tumor in the thoracic part of esophagus was detected by upper endoscopy. The biopsy showed endocrine cell carcinoma. PET/CT, endoscopy and an esophagogram showed that the patient had a 70-mm scaled type 2 tumor in the middle thoracic esophagus, and they also revealed lymph node metastases (no. 106recR). We diagnosed a cT3cN1cM0 cStage III tumor. With two courses of DCF treatment, both the primary tumor and lymph node metastases showed a partial response. We performed a subtotal esophagectomy with three-field lymph node dissection. The pathological examination of the resected specimens revealed no malignant cells in the esophagus or lymph nodes, and we concluded that the pathological effect of the DCF treatment was Grade 3. |
| Keywords | 食道癌（esophageal cancer） 内分泌細胞癌（endocrine cell carcinoma） DCF療法（DCF treatment） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-04-01 |
| Volume | volume126 |
| Issue | issue1 |
| Start Page | 39 |
| End Page | 43 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.39 |
| NAID | 130004505807 |
| Author | Nishikawa, Toshio| Takaoka, Munenori| Ohara, Toshiaki| Tomono, Yasuko| Hao, Huifang| Bao, Xiaohong| Fukazawa, Takuya| Wang, Zhigang| Sakurama, Kazufumi| Fujiwara, Yasuhiro| Motoki, Takayuki| Shirakawa, Yasuhiro| Yamatsuji, Tomoki| Tanaka, Noriaki| Fujiwara, Toshiyoshi| Naomoto, Yoshio| |
|---|---|
| Published Date | 2013-03 |
| Publication Title | Cancer Biology & Therapy |
| Volume | volume14 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Yoshida, Ryosuke| Tazawa, Hiroshi| Hashimoto, Yuuri| Yano, Shuya| Onishi, Teppei| Sasaki, Tsuyoshi| Shirakawa, Yasuhiro| Kishimoto, Hiroyuki| Uno, Futoshi| Nishizaki, Masahiko| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
|---|---|
| Published Date | 2012-11 |
| Publication Title | Cancer Immunology, Immunotherapy |
| Volume | volume61 |
| Issue | issue11 |
| Content Type | Journal Article |
| Author | Tanabe, Shunsuke| Shirakawa, Yasuhiro| Maeda, Naoaki| Ohara, Toshiaki| Noma, Kazuhiro| Sakurama, Kazufumi| Yanai, Hiroyuki| Yamatsuji, Tomoki| Naomoto, Yoshio| Fujiwara, Toshiyoshi| |
|---|---|
| Published Date | 2012-08-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume124 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Kuroda, Shinji| Fujiwara, Toshiya| Shirakawa, Yasuhiro| Yamasaki, Yasumoto| Yano, Syuya| Uno, Futoshi| Tazawa, Hiroshi| Hashimoto, Yuuri| Watanabe, Yuichi| Noma, Kazuhiro| Urata, Yasuo| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
|---|---|
| Published Date | 2011-08-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume123 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Watanabe, Nobuyuki| Takaoka, Munenori| Sakurama, Kazufumi| Tomono, Yasuko| Hatakeyama, Shinji| Ohmori, Osamu| Motoki, Takayuki| Shirakawa, Yasuhiro| Yamatsuji, Tomoki| Haisa, Minoru| Matsuoka, Junji| Beer, David G.| Nagatsuka, Hitoshi| Tanaka, Noriaki| Naomoto, Yoshio| |
|---|---|
| Published Date | 2010-04-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume122 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/15189 |
|---|---|
| Title Alternative | Quantitative evaluation method of swallowing hypofunctionby aging using Impedance Pharyngography (IPG) |
| FullText URL | 015_1_001_007.pdf |
| Author | Kusuhara, Toshimasa| Nakamura, Takao| Mori, Keiko| Yamamoto, Yoshitake| Shirakawa, Yasuhiro| Naomoto, Yoshio| |
| Abstract | インピーダンス咽頭図(Impedance Pharyngography, 以下IPG)は嚥下活動中の頸部電気インピーダンスを測定するもので,嚥下機能評価を簡便かつ無侵襲に行うことができる手法である｡IPG波形は嚥下機能を反映するものであるが嚥下機能の減退による波形への影響はその原因により様々である｡すなわち嚥下機能の状態が異なる被験者のIPG波形を直接比較･診断することは測定者の主観に依存することになり客観性に欠ける｡本研究では,まず青年健常者のNormal IPGをもとに嚥下機能が反映される波形の特徴を評価するパラメータとして,咽頭通過時間,インピーダンス変化率,類似度,嚥下音タイミングの4つを採用し,IPCを定量的に評価する手法を提案した｡また,この評価法を高齢者のIPGに適用し,青年健常者に比べて嚥下活動に関与する器官が円滑に活動を履行する能力に減退が生じる様子を定量的に示した｡ |
| Keywords | 嚥下活動 (swallowing) 嚥下障害 (dysphagia) 生体電気インピーダンス (bio-electrical impedance) インピーダンス咽頭図 (Impedance Pharyngography (IPG)) 嚥下機能評価 (assessment of swallowing function) |
| Publication Title | 岡山大学医学部保健学科紀要 |
| Published Date | 2004-12-15 |
| Volume | volume15 |
| Issue | issue1 |
| Start Page | 1 |
| End Page | 7 |
| ISSN | 1345-0948 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307994 |
| Author | Matsuoka, Junji| Naomoto, Yoshio| Tabata, Masahiro| Shirakawa, Yasuhiro| Hotta, Katsuyuki| Tanimoto, Mitsune| Tanaka, Noriaki| |
|---|---|
| Published Date | 2009-04-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume121 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | 木村 真士| 羽井佐 実| 高岡 宗徳| 伴 秀利| 上塚 大一| 大川 尚臣| 河島 留一| 白川 靖博| 繁光 薫| 山辻 知樹| 猶本 良夫| 田中 紀章| |
|---|---|
| Published Date | 2005-01-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume116 |
| Issue | issue3 |
| Content Type | Journal Article |
| Title Alternative | Two cases of acute pulmonary embolism after esophageal cancer operation |
|---|---|
| FullText URL | 118_41.pdf |
| Author | Kanazawa, Takashi| Watababe, Nobuyuki| Naomoto, Yoshio| Kobayashi, Masahiko| Shirakawa, Yasuhiro| Yamatsuji, Tomoki| Kobayashi, Naoya| Fujiwara, Tohsiyoshi| Matsubara, Nagahide| Iwagaki, Hiromi| Matsuoka, Junji| Tanaka, Noriaki| |
| Abstract | We encountered two cases of pulmonary embolism (PE)/venous thrombs (DVT) after surgery for esophageal cancer. The first case was a 58-year-old male. He underwent a subtotal esophagectomy and reconstruction using the stomach via the subcutaneus route. His postoperative course was stable; however, 13 days after the operation､ he had an elevated fever and pulmonary thrombi were observed on CT-scan screening. Scintigraphy confirmed the thrombi. An inferior vena cava filter (IVCF) was inserted and anti-coagulation therapy using heparin was started. His fever subsided, and 35 days after the operation, the thrombi disappeared. He was discharged thereafter and is being followed up using warfarin. The second case was a 74-year-old male. He also underwent subtotal esophagectomy and reconstruction using the stomach via the subcutaneus route. A central line was inserted via right femoral vein; however, the artery was injured and pressurization to the vessel was needed. His post-operative course was stable and symptom-free; however, ultrasound screening detected DVT in his right femoral vein. IVCF was mserted and anti-coagulation therapy was begun, thrombi disappeared 8 days after the therapy. |
| Keywords | 食道癌 (esophageal cancer) 肺塞栓症 (pulmonary embolism) 深部静脈血栓症 (deep venous thrombs) |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2006-05-01 |
| Volume | volume118 |
| Issue | issue1 |
| Start Page | 41 |
| End Page | 45 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright© 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma1947.118.1_41 |
| NAID | 10017417131 |
| Author | 平木 隆夫| 安井 光太郎| 三村 秀文| 郷原 英夫| 向井 敬| 長谷 聡一郎| 藤原 寛康| 田尻 展久| 猶本 良夫| 山辻 知樹| 白川 靖博| 浅海 信也| 中塚 秀輝| 花崎 元彦| 森田 潔| 田中 紀章| 金澤 右| |
|---|---|
| Published Date | 2006-09-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume118 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Ishii, Tatsuhiro| Murakami, Jun| Notohara, Kenji| Sasamoto, Hiromi| Kambara, Takeshi| Shirakawa, Yasuhiro| Naomoto, Yoshio| Ouchida, Mamoru| Shimizu, Kenji| Jeremy, R. Jass| Matsubara, Nagahide| Tanaka, Noriaki| |
|---|---|
| Published Date | 2007-09-03 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume119 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Naomoto, Yoshio| Yamatsuji, Tomoki| Shirakawa, Yasuhiro| Takaoka, Munenori| Fujiwara, Yasuhiro| Tanabe, Shunsuke| |
|---|---|
| Published Date | 2008-05-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume120 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | 白川 靖博| |
|---|---|
| Published Date | 2001-03-25 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
