ID | 61428 |
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Author |
Gobara, Hideo
Division of Medical Informatics, Okayama University Hospital
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Yamamoto, Akira
Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine
Komakic, Toshiyuki
Department of Radiology, Okayama University Hospital
Kitayama, Toshiaki
Department of Radiology, Otemae Hospital
Sakurai, Jun
Center for Innovative Clinical Medicine, Okayama University Hospital
Iguchi, Toshihiro
Department of Radiology, Okayama University Hospital
Matsui, Yusuke
Department of Radiology, Okayama University Hospital
Uka, Mayu
Department of Radiology, Okayama University Hospital
Tomita, Koji
Department of Radiology, Okayama University Hospital
Hiraki, Takao
Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
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Abstract | To assess the feasibility of needle tract ablation in liver tissue in ex vivo and in vivo animal models using a cryo-probe and electrosurgical device. The experimental device is made by inserting a cryoprobe through an intro-ducer sheath for insulation, with 2-cm of probe tip projecting out. A beagle liver was punctured by the device, and electric current was applied at 30-W with the electrosurgical knife touching the non-insulated device base. The discolored area of cut surface along the device was evaluated in 5 application-time groups (5 , 10 , 15 , 20, or 25 seconds). An ex vivo experiment was performed to determine an ablation algorithm with an appropriate application time by comparison with radiofrequency ablation (RFA) results. Thereafter, an in vivo experiment was performed to verify the algorithm’s feasibility. In the ex vivo model, the cut surface demonstrated different amounts of discolored area according to the application time. The total discolored area in the 20-seconds group was similar to that by RFA. In the in vivo model, the liver did not bleed, the total discolored area was similar to that ex vivo, and coagulation necrosis was confirmed by photomicrograph. Needle tract ablation can be per-formed using the experimental device and electrosurgical device.
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Keywords | needle tract ablation
cryoablation
electrosurgical device
animal
liver
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Amo Type | Original Article
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Publication Title |
Acta Medica Okayama
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Published Date | 2021-02
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Volume | volume75
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Issue | issue1
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Publisher | Okayama University Medical School
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Start Page | 9
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End Page | 14
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School
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File Version | publisher
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Refereed |
True
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PubMed ID |