Ono, Mitsuaki - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Bioconversion and Metabolic Fate of the n-1 Polyunsaturated Fatty Acids, 6,9,12,15- Hexadecatetraenoic (C16:4 n-1) and 8,11,14,17- Octadecatetraenoic (C18:4 n-1) Acids, in HepG2 Cells

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Author	Sugimoto, Koki\| Nishiguchi, Hideto\| Hosomi, Ryota\| Tanizaki, Toshifumi\| Tsushima, Tadahiro\| Baba, Naomichi\| Misawa, Yoshihisa\| Wang, Ziyi\| Ono, Mitsuaki\| Murakami, Yuki\| Kanda, Seiji\| Fukunaga, Kenji\|
Keywords	n-1 polyunsaturated fatty acids hexadecatetraenoic acid octadecatetraenoic acid HepG2
Published Date	2025
Publication Title	Journal of Oleo Science
Volume	volume74
Issue	issue11
Publisher	Japan Oil Chemists' Society
Start Page	1023
End Page	1032
ISSN	1345-8957
NCID	AA11503337
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 by Japan Oil Chemists' Society
File Version	publisher
PubMed ID	41183904
DOI	10.5650/jos.ess25120
CRID	1390024725206428544
Web of Science KeyUT	001638722200006
Related Url	isVersionOf https://doi.org/

Single cell spatial transcriptomics links Wnt signaling disruption to extracellular matrix development in a cleft palate model

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Author	Piña, Jeremie Oliver\| Raju, Resmi\| Stipano, Evan\| Myo, Aye Chan\| Wang, Ziyi\| Ono, Mitsuaki\| Chattaraj, Parna\| Furukawa, Masae\| D’Souza, Rena N.\|
Keywords	Spatial biology Cleft palate Genomics Single cell Gene expression Profiling Extracellular matrix Wnt Transcriptome
Published Date	2025-08-13
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	29639
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	publisher
PubMed ID	40804270
DOI	10.1038/s41598-025-14807-1
Web of Science KeyUT	001551327800020
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-14807-1

Critical Requirement of Senescence-Associated CCN3 Expression in CD44-Positive Stem Cells for Osteoarthritis Progression

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Author	Habumugisha, Janvier\| Okuda, Ryuichiro\| Hirose, Kazuki\| Kuwahara, Miho\| Wang, Ziyi\| Ono, Mitsuaki\| Kamioka, Hiroshi\| Kubota, Satoshi\| Hattori, Takako\|
Keywords	articular cartilage mesenchymal stem cells nephroblastoma overexpressed protein osteoarthritis
Published Date	2025-10-02
Publication Title	International Journal of Molecular Sciences
Volume	volume26
Issue	issue19
Publisher	MDPI AG
Start Page	9630
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 by the authors.
File Version	publisher
PubMed ID	41096895
DOI	10.3390/ijms26199630
Web of Science KeyUT	001593630300001
Related Url	isVersionOf https://doi.org/10.3390/ijms26199630

Macrophages modulate mesenchymal stem cell function via tumor necrosis factor alpha in tooth extraction model

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Author	Mun, Aung Ye\| Akiyama, Kentaro\| Wang, Ziyi\| Zhang, Jiewen\| Kitagawa, Wakana\| Kohno, Teisaku\| Tagashira, Ryuji\| Ishibashi, Kei\| Matsunaga, Naoya\| Zou, Tingling\| Ono, Mitsuaki\| Kuboki, Takuo\|
Keywords	cytokines dental biology injury healing osteoimmunology stem cells
Published Date	2024-07-04
Publication Title	JBMR Plus
Volume	volume8
Issue	issue8
Publisher	Oxford University Press
Start Page	ziae085
ISSN	2473-4039
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024.
File Version	publisher
PubMed ID	39086598
DOI	10.1093/jbmrpl/ziae085
Web of Science KeyUT	001281090900001
Related Url	isVersionOf https://doi.org/10.1093/jbmrpl/ziae085

Resolvin D2-induced reparative dentin and pulp stem cells after pulpotomy in a rat model

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Author	Yoneda, Mitsuhiro\| Ideguchi, Hidetaka\| Nakamura, Shin\| Arias, Zulema\| Ono, Mitsuaki\| Omori, Kazuhiro\| Yamamoto, Tadashi\| Takashiba, Shogo\|
Keywords	Dental pulp Regeneration Pulp-capping agents Specialized pro-resolving mediators Resolvin D2 Calcification Cytokine TRPA1 Animal model
Published Date	2024-07-15
Publication Title	Heliyon
Volume	volume10
Issue	issue13
Publisher	Elsevier
Start Page	e34206
ISSN	2405-8440
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Authors.
File Version	publisher
DOI	10.1016/j.heliyon.2024.e34206
Web of Science KeyUT	001267808100001
Related Url	isVersionOf https://doi.org/10.1016/j.heliyon.2024.e34206

Local E-rhBMP-2/β-TCP Application Rescues Osteocyte Dendritic Integrity and Reduces Microstructural Damage in Alveolar Bone Post-Extraction in MRONJ-like Mouse Model

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Author	Dang, Anh Tuan\| Ono, Mitsuaki\| Wang, Ziyi\| Tosa, Ikue\| Hara, Emilio Satoshi\| Mikai, Akihiro\| Kitagawa, Wakana\| Yonezawa, Tomoko\| Kuboki, Takuo\| Oohashi, Toshitaka\|
Keywords	medication-related osteonecrosis of the jaw BMP-2 osteocyte dendritic network microcrack accumulation bone remodeling
Published Date	2024-06-17
Publication Title	International Journal of Molecular Sciences
Volume	volume25
Issue	issue12
Publisher	MDPI
Start Page	6648
ISSN	1661-6596
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
PubMed ID	38928355
DOI	10.3390/ijms25126648
Web of Science KeyUT	001256547900001
Related Url	isVersionOf https://doi.org/10.3390/ijms25126648

Exploring the Regulators of Keratinization: Role of BMP-2 in Oral Mucosa

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Author	Mu, Xindi\| Ono, Mitsuaki\| Nguyen, Ha Thi Thu\| Wang, Ziyi\| Zhao, Kun\| Komori, Taishi\| Yonezawa, Tomoko\| Kuboki, Takuo\| Oohashi, Toshitaka\|
Keywords	cell differentiation epithelia growth factor(s) bioinformatics extracellular matrix (ECM) mucocutaneous disorders
Published Date	2024-05-09
Publication Title	Cells
Volume	volume13
Issue	issue10
Publisher	MDPI
Start Page	807
ISSN	2073-4409
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
PubMed ID	38786031
DOI	10.3390/cells13100807
Web of Science KeyUT	001232270600001
Related Url	isVersionOf https://doi.org/10.3390/cells13100807

Antitumor activity of α-pinene in T-cell tumors

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Author	Abe, Masaya\| Asada, Noboru\| Kimura, Maiko\| Fukui, Chie\| Yamada, Daisuke\| Wang, Ziyi\| Miyake, Masayuki\| Takarada, Takeshi\| Ono, Mitsuaki\| Aoe, Michinori\| Kitamura, Wataru\| Matsuda, Masayuki\| Moriyama, Takashi\| Matsumura, Akifumi\| Maeda, Yoshinobu\|
Keywords	alpha-pinene apoptosis hematologic malignancies lymphoblastic leukemia, acute, T-cell T-cell lymphoma
Published Date	2024-01-26
Publication Title	Cancer Science
Volume	volume115
Issue	issue4
Publisher	Wiley
Start Page	1317
End Page	1332
ISSN	1347-9032
NCID	AA11808050
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Authors.
File Version	publisher
PubMed ID	38279512
DOI	10.1111/cas.16086
Web of Science KeyUT	001149672000001
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The Fungal Metabolite (+)-Terrein Abrogates Inflammatory Bone Resorption via the Suppression of TNF-α Production in a Ligature-Induced Periodontitis Mouse Model

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Author	Sako, Hidefumi\| Omori, Kazuhiro\| Nakayama, Masaaki\| Mandai, Hiroki\| Ideguchi, Hidetaka\| Yoshimura-Nakagawa, Saki\| Sakaida, Kyosuke\| Nagata-Kamei, Chiaki\| Kobayashi, Hiroya\| Ishii, Satoki\| Ono, Mitsuaki\| Ibaragi, Soichiro\| Yamamoto, Tadashi\| Suga, Seiji\| Takashiba, Shogo\|
Keywords	synthetic (+)-terrein periodontitis TNF-α
Published Date	2023-03-03
Publication Title	Journal of Fungi
Volume	volume9
Issue	issue3
Publisher	MDPI
Start Page	314
ISSN	2309-608X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 by the authors.
File Version	publisher
PubMed ID	36983482
DOI	10.3390/jof9030314
Web of Science KeyUT	000960078500001
Related Url	isVersionOf https://doi.org/10.3390/jof9030314

Cysteinyl leukotriene receptor 1 is dispensable for osteoclast differentiation and bone resorption

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Author	Fujita, Hirofumi\| Ando, Aoi\| Mizusawa, Yohei\| Ono, Mitsuaki\| Hattori, Takako\| Habuta, Munenori\| Oohashi, Toshitaka\| Kubota, Satoshi\| Ohuchi, Hideyo\|
Published Date	2022-11-17
Publication Title	Plos One
Volume	volume17
Issue	issue11
Publisher	Public Library Science
Start Page	e0277307
ISSN	1932-6203
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 Fujita et al.
File Version	publisher
PubMed ID	36395281
DOI	10.1371/journal.pone.0277307
Web of Science KeyUT	000926013600060
Related Url	isVersionOf https://doi.org/10.1371/journal.pone.0277307

SOD3 Expression in Tumor Stroma Provides the Tumor Vessel Maturity in Oral Squamous Cell Carcinoma

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Author	Oo, May Wathone\| Kawai, Hotaka\| Eain, Htoo Shwe\| Soe, Yamin\| Takabatake, Kiyofumi\| Sanou, Sho\| Shan, Qiusheng\| Inada, Yasunori\| Fujii, Masae\| Fukuhara, Yoko\| Wang, Ziyi\| Sukegawa, Shintaro\| Ono, Mitsuaki\| Nakano, Keisuke\| Nagatsuka, Hitoshi\|
Keywords	oral squamous cell carcinoma tumor microenvironment tumor stroma tumor vascularization extracellular superoxide dismutase (SOD3) vascular endothelial cadherin (Ve-cadherin)
Published Date	2022-10-28
Publication Title	Biomedicines
Volume	volume10
Issue	issue11
Publisher	MDPI
Start Page	2729
ISSN	2227-9059
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 by the authors.
File Version	publisher
PubMed ID	36359248
DOI	10.3390/biomedicines10112729
Web of Science KeyUT	000881045700001
Related Url	isVersionOf https://doi.org/10.3390/biomedicines10112729

Suppression of Bone Necrosis around Tooth Extraction Socket in a MRONJ-like Mouse Model by E-rhBMP-2 Containing Artificial Bone Graft Administration

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Author	Tanaka, Yukie\| Aung, Kyaw Thu\| Ono, Mitsuaki\| Mikai, Akihiro\| Dang, Anh Tuan\| Hara, Emilio Satoshi\| Tosa, Ikue\| Ishibashi, Kei\| Ono-Kimura, Aya\| Nawachi, Kumiko\| Kuboki, Takuo\| Oohashi, Toshitaka\|
Keywords	medication-related osteonecrosis of the jaw BMP-2 beta-tricalcium phosphate bone formation bone necrosis
Published Date	2021-11-26
Publication Title	International Journal Of Molecular Sciences
Volume	volume22
Issue	issue23
Publisher	MDPI
Start Page	12823
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
PubMed ID	34884630
DOI	10.3390/ijms222312823
Web of Science KeyUT	000735802700001
Related Url	isVersionOf https://doi.org/10.3390/ijms222312823

The Fungal Metabolite (+)-Terrein Abrogates Ovariectomy-Induced Bone Loss and Receptor Activator of Nuclear Factor-kappa B Ligand-Induced Osteoclastogenesis by Suppressing Protein Kinase-C alpha/beta II Phosphorylation

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Author	Sakaida, Kyosuke\| Omori, Kazuhiro\| Nakayama, Masaaki\| Mandai, Hiroki\| Nakagawa, Saki\| Sako, Hidefumi\| Kamei, Chiaki\| Yamamoto, Satoshi\| Kobayashi, Hiroya\| Ishii, Satoki\| Ono, Mitsuaki\| Ibaragi, Soichiro\| Yamashiro, Keisuke\| Yamamoto, Tadashi\| Suga, Seiji\| Takashiba, Shogo\|
Keywords	(+)-terrein ovariectomy osteoporosis RANKL PKC
Published Date	2021-06-08
Publication Title	Frontiers In Pharmacology
Volume	volume12
Publisher	Frontiers Media SA
Start Page	674366
ISSN	1663-9812
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Sakaida, Omori, Nakayama, Mandai, Nakagawa, Sako, Kamei, Yamamoto, Kobayashi, Ishii, Ono, Ibaragi, Yamashiro, Yamamoto, Suga and Takashiba.
File Version	publisher
PubMed ID	34168561
DOI	10.3389/fphar.2021.674366
Web of Science KeyUT	000664090900001
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Lack of collagen alpha 6(IV) chain in mice does not cause severe-to-profound hearing loss or cochlear malformation, a distinct phenotype from nonsyndromic hearing loss with COL4A6 missense mutation

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Author	Tang, Shaoying\| Yonezawa, Tomoko\| Maeda, Yukihide\| Ono, Mitsuaki\| Maeba, Takahiro\| Miyoshi, Toru\| Momota, Ryusuke\| Tomono, Yasuko\| Oohashi, Toshitaka\|
Published Date	2021-04-13
Publication Title	PLoS ONE
Volume	volume16
Issue	issue4
Publisher	Public Library Science
Start Page	e0249909
ISSN	1932-6203
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Tang et al.
File Version	publisher
PubMed ID	33848312
DOI	10.1371/journal.pone.0249909
NAID	120007042400
Web of Science KeyUT	000640373500028
Related Url	isVersionOf https://doi.org/10.1371/journal.pone.0249909

Tryptophan and Kynurenine Enhances the Stemness and Osteogenic Differentiation of Bone Marrow-Derived Mesenchymal Stromal Cells In Vitro and In Vivo

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Author	Pham, Hai Thanh\| Ono, Mitsuaki\| Hara, Emilio Satoshi\| Nguyen, Ha Thi Thu\| Dang, Anh Tuan\| Do, Hang Thuy\| Komori, Taishi\| Tosa, Ikue\| Hazehara-Kunitomo, Yuri\| Yoshioka, Yuya\| Oida, Yasutaka\| Akiyama, Kentaro\| Kuboki, Takuo\|
Keywords	amino acid mesenchymal stromal cells stemness tryptophan kynurenine osteogenesis adipogenesis screening injury/fracture healing anabolics
Published Date	2021-01-04
Publication Title	Materials
Volume	volume14
Issue	issue1
Publisher	MDPI
Start Page	208
ISSN	1996-1944
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
PubMed ID	33406724
DOI	10.3390/ma14010208
Web of Science KeyUT	000606251400001
Related Url	isVersionOf https://doi.org/10.3390/ma14010208

Distinct Osteogenic Potentials of BMP-2 and FGF-2 in Extramedullary and Medullary Microenvironments

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Author	Nosho, Shuji\| Tosa, Ikue\| Ono, Mitsuaki\| Hara, Emilio Satoshi\| Ishibashi, Kei\| Mikai, Akihiro\| Tanaka, Yukie\| Kimura-Ono, Aya\| Komori, Taishi\| Maekawa, Kenji\| Kuboki, Takuo\| Oohashi, Toshitaka\|
Keywords	BMP-2 FGF-2 bone formation bone marrow
Published Date	2020-10-27
Publication Title	International Journal of Molecular Sciences
Volume	volume21
Issue	issue21
Publisher	MDPI
Start Page	7967
ISSN	1422-0067
NCID	AA12038549
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	33120952
DOI	10.3390/ijms21217967
Web of Science KeyUT	000588995400001
Related Url	isVersionOf https://doi.org/10.3390/ijms21217967

BMP-2/beta-TCP Local Delivery for Bone Regeneration in MRONJ-Like Mouse Model

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Author	Mikai, Akihiro\| Ono, Mitsuaki\| Tosa, Ikue\| Ha Thi Thu, Nguyen\| Hara, Emilio Satoshi\| Nosho, Shuji\| Kimura-Ono, Aya\| Nawachi, Kumiko\| Takarada, Takeshi\| Kuboki, Takuo\| Oohashi, Toshitaka\|
Keywords	BMP-2 MRONJ bone regeneration
Published Date	2020-09-24
Publication Title	International Journal of Molecular Sciences
Volume	volume21
Issue	issue19
Publisher	MDPI
Start Page	7028
ISSN	1422-0067
NCID	AA12038549
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	32987737
DOI	10.3390/ijms21197028
Web of Science KeyUT	000586659200001
Related Url	isVersionOf https://doi.org/10.3390/ijms21197028

Aging-Affected MSC Functions and Severity of Periodontal Tissue Destruction in a Ligature-Induced Mouse Periodontitis Model

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Author	Aung, Kyaw Thu\| Akiyama, Kentaro\| Kunitomo, Masayoshi\| Mun, Aung Ye\| Tosa, Ikue\| Nguyen, Ha Thi Thu\| Zhang, Jiewen\| Kohno, Teisaku\| Ono, Mitsuaki\| Hara, Emilio Satoshi\| Kuboki, Takuo\|
Keywords	mesenchymal stem cell aging tissue destruction periodontitis immunomodulation bone resorption
Published Date	2020-10-30
Publication Title	International Journal of Molecular Sciences
Volume	volume21
Issue	issue21
Publisher	MDPI
Start Page	8103
ISSN	1422-0067
NCID	AA12038549
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	33143068
DOI	10.3390/ijms21218103
Web of Science KeyUT	000589055400001
Related Url	isVersionOf https://doi.org/10.3390/ijms21218103

CCN3 (NOV) Drives Degradative Changes in Aging Articular Cartilage

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Author	Kuwahara, Miho\| Kadoya, Koichi\| Kondo, Sei\| Fu, Shanqi\| Miyake, Yoshiko\| Ogo, Ayako\| Ono, Mitsuaki\| Furumatsu, Takayuki\| Nakata, Eiji\| Sasaki, Takako\| Minagi, Shogo\| Takigawa, Masaharu\| Kubota, Satoshi\| Hattori, Takako\|
Keywords	cellular communication network factor 3 CCN3 NOV primary chondrocytes aging oxidative stress senescence p21 p53 SASP
Published Date	2020-10-13
Publication Title	International Journal of Molecular Sciences
Volume	volume21
Issue	issue20
Publisher	MDPI
Start Page	7556
ISSN	1422-0067
NCID	AA12038549
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	33066270
DOI	10.3390/ijms21207556
Web of Science KeyUT	000585557400001
Related Url	isVersionOf https://doi.org/10.3390/ijms21207556

OstemiR: A Novel Panel of MicroRNA Biomarkers in Osteoblastic and Osteocytic Differentiation from Mesencymal Stem Cells

Author	Eguchi, Takanori\| Watanabe, Ken\| Hara, Emilio Satoshi\| Ono, Mitsuaki\| Kuboki, Takuo\| Stuart K., Calderwood\|
Published Date	2013-03-22
Publication Title	PLOS ONE
Volume	volume8
Issue	issue3
Content Type	Journal Article