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Author Ohira, Akiko| Maki, Jota| Ageta, Kohei| Nakato, Hikari| Oba, Hikaru| Mitoma, Tomohiro| Mishima, Sakurako| Tani, Kazumasa| Kirino, Satoe| Eto, Eriko| Nakao, Atsunori| Masuyama, Hisashi|
Keywords Simulation-based education Ultrasound Paramedics FAST
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-54779-2|
Published Date 2024-02-20
Publication Title Scientific Reports
Volume volume14
Issue issue1
Publisher Nature Portfolio
Start Page 4190
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38378769
DOI 10.1038/s41598-024-54779-2
Web of Science KeyUT 001173675500048
Related Url isVersionOf https://doi.org/10.1038/s41598-024-54779-2
FullText URL fulltext20230424-01.pdf
Author Mishima, Sakurako| Mitsui, Takashi| Tani, Kazumasa| Maki, Jota| Eto, Eriko| Hayata, Kei| Washio, Yosuke| Yoshimoto, Junko| Tsukahara, Hirokazu| Masuyama, Hisashi|
Keywords Short stature catch-up growth small-for-gestational age premature birth hypertensive disorders of pregnancy
Published Date 2023-03-08
Publication Title Hypertension in Pregnancy
Volume volume42
Issue issue1
Publisher Taylor and Francis
Start Page 2187623
ISSN 1064-1955
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Author(s).
File Version publisher
PubMed ID 36891613
DOI 10.1080/10641955.2023.2187623
Web of Science KeyUT 000953321900001
Related Url isVersionOf https://doi.org/10.1080/10641955.2023.2187623
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Author Mitoma, Tomohiro| Maki, Jota| Ooba, Hikaru| Eto, Eriko| Takahashi, Kasumi| Kondo, Tsunemasa| Ikeda, Tomohiro| Sakamoto, Yoko| Mitsuhashi, Toshiharu| Masuyama, Hisashi|
Keywords Oestrogen replacement therapy Knee osteoarthritis Muscle resistance exercise Sarcopenia Physical performance
Published Date 2023-02-18
Publication Title BMC Geriatrics
Volume volume23
Issue issue1
Publisher BMC
Start Page 104
ISSN 1471-2318
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 36800940
DOI 10.1186/s12877-023-03828-y
Web of Science KeyUT 000936860000001
Related Url isVersionOf https://doi.org/10.1186/s12877-023-03828-y
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Author Mitoma, Tomohiro| Hayata, Kei| Yokohata, Satomi| Ohira, Akiko| Kashino, Chiaki| Kirino, Satoe| Tani, Kazumasa| Maki, Jota| Eto, Eriko| Masuyama, Hisashi|
Keywords Lupus Myometrium Placenta accreta spectrum Estrogen Uterine atony
Published Date 2022-07-02
Publication Title BMC Pregnancy And Childbirth
Volume volume22
Issue issue1
Publisher BMC
Start Page 535
ISSN 1471-2393
NCID AA12035416
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 35780086
DOI 10.1186/s12884-022-04864-z
Web of Science KeyUT 000820223600001
Related Url isVersionOf https://doi.org/10.1186/s12884-022-04864-z
JaLCDOI 10.18926/AMO/62816
FullText URL 75_6_745.pdf
Author Hayata, Kei| Mishima, Sakurako| Ohira, Akiko| Tani, Kazumasa| Maki, Jota| Eto, Eriko| Ogawa, Chikako| Masuyama, Hisashi|
Abstract NIPT is non-definitive testing to estimate the possibility that fetuses have trisomy 21, trisomy 18, or trisomy 13. However, in NIPT-positive and indeterminate cases, rare chromosomal disease may become apparent, requiring advanced genetic considerations and counseling skills. We experienced two such cases, a trisomy 21 mosaicism case triggered by NIPT-positive status and 18q deletion syndrome triggered by NIPT-indeterminate status. These cases have two clinical implications for NIPT. First, it was revealed that trisomy mosaicism might be found in NIPT-positive cases that have lower Z-Scores than those inferred from the fraction of fetal cfDNA in the case of standard trisomy. Second, it is possible that microdeletion syndrome could be the reason for an indeterminate NIPT result. Today’s genetic counseling requires more expertise in ethics and communication as well as genetic science because NIPT can lead to totally unexpected results.
Keywords NIPT massively parallel sequencing trisomy 21 mosaicism 18q-deletion syndrome genetic counseling
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-12
Volume volume75
Issue issue6
Publisher Okayama University Medical School
Start Page 745
End Page 750
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34955544
Web of Science KeyUT 000735319800002
NAID 120007180276
JaLCDOI 10.18926/AMO/62806
FullText URL 75_6_677.pdf
Author Tani Kazumasa| Mitsui, Takashi| Mishima, Sakurako| Ohira, Akiko| Maki, Jota| Eto, Eriko| Hayata, Kei| Nakamura, Keiichiro| Masuyama, Hisashi|
Abstract Extravillous trophoblast (EVT) invasion is important for embryo implantation, placental development, and successful remodeling of the uterine spiral artery. Endocrine gland derived-vascular endothelial growth factor (EG-VEGF) and matrix metalloproteinases (MMPs) are implicated in EVT invasion; however, the high con-centrations found in pregnancy pathologies have not been investigated in non-tumor trophoblasts. The roles of EG-VEGF, prokineticin receptors (PROKR1/2), MMP-2, and MMP-9 in EVT invasion during spiral artery remodeling were evaluated using human EVT from HTR-8/SVneo cell lines. The expression of MMP-2, MMP-9, and mitogen-activated protein kinase (MAPK), and Akt pathways in HTR-8/SVneo cells treated with recom-binant EG-VEGF alongside anti-PROKR1 and/or anti-PROKR2 antibodies was evaluated using quantitative reverse transcription-PCR and western blotting. Wound-healing and cell invasion assays were performed to assess the migration and invasion of these treated cells. Interestingly, 20 nM EG-VEGF activated ERK1/2 sig-naling and upregulated MMP-2 and MMP-9. This effect was suppressed by anti-PROKR2 antibody via ERK1/2 downregulation. Anti-PROKR2 antibody inhibited the migration and invasion of EG-VEGF-stimulated HTR-8/SVneo cells. Elevated concentrations of EG-VEGF enhance EVT invasion in a human trophoblast cell line by upregulating MMP-2 and MMP-9 via PROKR2. These new insights into the regulation of epithelial cell invasion may help in developing therapeutic interventions for placental-related diseases during pregnancy.
Keywords endocrine gland-derived vascular endothelial growth factor prokineticin extravillous trophoblast matrix metalloproteinase obstetric diseases
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-12
Volume volume75
Issue issue6
Publisher Okayama University Medical School
Start Page 677
End Page 684
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34955534
Web of Science KeyUT 000735297900002
NAID 120007180286
JaLCDOI 10.18926/AMO/62395
FullText URL 75_4_439.pdf
Author Mitsui, Takashi| Mishima, Sakurako| Tani, Kazumasa| Maki, Jota| Eto, Eriko| Hayata, Kei| Masuyama, Hisashi|
Abstract Early diagnosis and therapy are important in a cesarean scar pregnancy (CSP), which can cause uterine rupture with resultant massive bleeding. However, there are some reports of CSPs continued to term. The optimal management of CSPs remains unclear; therefore, we investigated the clinical courses of CSPs diagnosed and treated at perinatal institutions in the Chugoku and Shikoku regions of Japan. We enrolled 60 women diag-nosed with CSP at 21 institutions from January 2006 to December 2015. Of the 60 women diagnosed with CSP, 57 were treated. Pregnancy was terminated in 48 women and continued in 9. Thirteen women underwent transabdominal hysterectomy; they experienced no postoperative complications or allogeneic blood transfu-sion. Nine women received therapies such as dilation and curettage, and 26 received non-surgical therapies such as methotrexate and topical administration of potassium chloride. Among 9 women who chose to con-tinue with their CSP, 7 successfully delivered newborns, 2 had uterine ruptures in the second trimester, and all women required transabdominal hysterectomy. Diagnosis and therapy in the first trimester of pregnancy are important in the management strategy of a CSP. When continuing a CSP, the risk of uterine rupture and trans-abdominal hysterectomy must be considered.
Keywords cesarean scar pregnancy uterine rupture hysterectomy methotrexate potassium chloride
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 439
End Page 445
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511610
Web of Science KeyUT 000697944600005
NAID 120007146038
FullText URL fulltext.pdf
Author Mitsui, Takashi| Mishima, Sakurako| Ohira, Akiko| Tani, Kazumasa| Maki, Jota| Eto, Eriko| Hayata, Kei| Masuyama, Hisashi|
Keywords Cesarean scar pregnancy Gestational sac Human chorionic gonadotropin Systemic methotrexate
Published Date 2021-05
Publication Title Taiwanese Journal of Obstetrics & Gynecology
Volume volume60
Issue issue3
Publisher ELSEVIER TAIWAN
Start Page 454
End Page 457
ISSN 1028-4559
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Taiwan Association of Obstetrics & Gynecology.
File Version publisher
PubMed ID 33966727
NAID 120007045005
DOI 10.1016/j.tjog.2021.03.011
Web of Science KeyUT 000651121800011
Related Url isVersionOf https://doi.org/10.1016/j.tjog.2021.03.011
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Author Eto, Eriko| Mitsui, Takashi| Tamada, Shoko| Maki, Jota| Hayata, Kei| Masuyama, Hisashi|
Keywords adrenal incidental tumor pregnancy subclinical Cushing's syndrome superimposed preeclampsia
Published Date 2020-02-03
Publication Title Clinical Case Reports
Volume volume8
Issue issue3
Publisher Wiley
Start Page 481
End Page 483
ISSN 2050-0904
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
PubMed ID 32185040
DOI 10.1002/ccr3.2592
Web of Science KeyUT 000519370400016
Related Url isVersionOf https://doi.org/10.1002/ccr3.2592
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Author Eto, Eriko| Maki, Jota| Akagi, Teiji| Ito, Hiroshi| Masuyama, Hisashi|
Keywords Anticoagulant Fontan circulation Labor analgesia Obstetrical complications Pregnancy
Published Date 2019-12-30
Publication Title Journal of Cardiology Cases
Volume volume21
Issue issue4
Publisher Elsevier
Start Page 161
End Page 163
ISSN 18785409
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 Published by Elsevier Ltd on behalf of Japanese College of Cardiology.
File Version publisher
PubMed ID 32256867
DOI 10.1016/j.jccase.2019.12.005
Related Url isVersionOf https://doi.org/10.1016/j.jccase.2019.12.005