このエントリーをはてなブックマークに追加
ID 56894
Sort Key
3
Title Alternative
The mammalian pigmentary system - a model experimental system for exploring the functional divergence of a differentiated cell type
FullText URL
Author
Yamamoto, Hiroaki Faculty of Bioscience Nagahama Institute of Bio-Science and Technology
Abstract
There are two cell lineages of mammalian melanin pigment cells, one that leads to retinal pigment epithelium (RPE) cells in the eye from the optic cup and the other leading to melanocytes from vertebrate-specific neural crest cells. Melanocyte precursors have high mobility and migrate and settle into various tissues and organs, including the skin, choroid, inner ear, heart, brain, adipose tissue, lung, etc. It is well known that RPE cells are essential for visual acuity and that melanocytes in the skin provide protection against UV-damage. So, what is the function of extracutaneous melanocytes that are distributed elsewhere in the body where only very small amounts of light illuminate their existence? Here I would like to briefly introduce our research history and then discuss the important roles of melanocytes in the inner ear that are indispensable for hearing ability and those in the choroid where they seem to contribute to maintaining the structures of their habitats.
Note
特別講演要旨(Summary of Commemorational Lecture)
Publication Title
Proceedings of Okayama Association for Laboratory Animal Science
Published Date
2019-06
Volume
volume35
Publisher
岡山実験動物研究会
Publisher Alternative
Okayama Association for Laboratory Animal Science
Start Page
2
End Page
8
Content Type
Conference Paper
OAI-PMH Set
岡山大学
language
日本語
File Version
publisher
Eprints Journal Name
poalas