Author Nishiyama, Syoichi|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Ono, Kaname|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Ono, Kaname|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Sato, Toshio|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Sato, Toshio|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Title Alternative The nucleus accumbens septi and the limbic seizure: Studied by kindling preparation.
FullText URL 94_87.pdf
Author Yamashita, Motoshi|
Abstract An antagonistic relationship between epilepsy and psychosis has been claimed. On the other hand, abnormality of the N. accumbens is thought to be involved in schizophrenia and temporal lobe epilepsy. In order to examine the role of the N. accumbens in limbic seizure and psychosis, the following were studied: 1. Amygdaloid kindling and the functional change of the N. accumbens, 2. Accumbens kindling, 3. Functional change of limbic nuclei following the accumbens kindling, and 4. The effects of lesioning of the N. accumbens on the amygdaloid kindling. The results were as follows: 1. The amygdaloid kindling induced epileptic focus and positive transfer into the N. accumbens. 2. The kindling phenomenon was confirmed positive by repeated stimulation of the N. accumbens. Clinicoelectrographic seizure development during the N. accumbens kindling resembled that of amygdaloid kindling. The mean minimum intensities to induce afterdischarge and kindling rate were 620μA and 23days, respectively. 3. Positive transfer was found in the N. amygdala and hippocampus following the accumbens kindling. 4. Lesioning of the N. accumbens had no effect on amygdaloid seizure development, but lowered the threshold intensity to induce amygdaloid afterdischarge after kindling. It was concluded that the N. accumbens and the N. amygdala formed epileptic hyperexcitability reciprocally and that the N. accumbens had an inhibitory effect on the limbic seizure, but no effect on the developed amygdaloid kindling.
Keywords 側坐核 燃え上がり現象 辺縁系発作 中脳辺縁ドパミン系 側頭葉てんかん
Publication Title 岡山医学会雑誌
Published Date 1982-02-28
Volume volume94
Issue issue1-2
Start Page 87
End Page 102
ISSN 0030-1558
Official Url https://www.jstage.jst.go.jp/article/joma1947/94/1-2/94_1-2_87/_article/-char/ja/|
Related Url http://www.okayama-u.ac.jp/user/oma/index.html
language Japanese
Copyright Holders 岡山医学会
File Version publisher
Author Kouno, Mitsunobu|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Kageyama, Keiko|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Kageyama, Keiko|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Kira, Shohei| Izumi, Takehiro| Ogata, Masana| Tongu, Yasumasa| Aji, Toshiki| Inatomi, Seiiti| Tada, Keiichi| Suguri, Setsuo| Ichikawa, Junichi| Matsuda, Kiyoshi|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Takaya, Masatoshi|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Takaya, Masatoshi|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Tokiwa, Takayoshi| Nishizaki, Shizuo| Sato, Jiro|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Sato, Yuji|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article
Author Furuta, Yoshio|
Published Date 1982-02-28
Publication Title 岡山医学会雑誌
Volume volume94
Issue issue1-2
Content Type Journal Article