ID | 17277 |
Eprint ID | 17277
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FullText URL | |
Title Alternative | Endocrinological study on Sheehan's syndrome
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Author |
Asaoka, Katsushi
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Abstract | The clinical history, laboratory data, and hypothalamic-pituitary-axis were investigated in 8 patients with Sheehan's syndrome. 2 patients had panhypopituitarism while 6 patients had selective pituitary deficiencies. Hypothalamic-pituitary-adrenal-axis in 2 patients with Sheehan's syndrome was impaired when the response to metopirone, but not to insulin-induced hypoglycemia. The interpretation of this difference is complicated in secondary hypothyroidism, and better preserved in the response to metopirone than to insulin-induced-hypoglycemia. The imbalance of LH and FSH response to LHRH in 2 cases (a blunted LH response in the presence of normal FSH response) may account for the complication of secondary hypothyroidism. The variety of Sheehan's syndrome was observed, for example that one case without history of postpartum hemorrhage or shock, and others with pregnancy after onset of Sheehan's syndrome. The duration of illness at the time of diagnosis ranged from 1.5 years to 11 years with an average of 6.5 years. In the future, a follow-up investigation of women with the history of postpartum hemorrhage or shock is necessary.
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Published Date | 1977-12-30
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Publication Title |
岡山医学会雑誌
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Publication Title Alternative | Journal of Okayama Medical Association
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Volume | volume89
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Issue | issue11-12
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Publisher | 岡山医学会
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Publisher Alternative | Okayama Medical Association
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Start Page | 1655
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End Page | 1664
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ISSN | 0030-1558
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NCID | AN00032489
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Content Type |
Journal Article
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Official Url | https://www.jstage.jst.go.jp/article/joma1947/89/11-12/89_11-12_1655/_article/-char/ja/
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Related Url | http://www.okayama-u.ac.jp/user/oma/
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language |
Japanese
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Copyright Holders | 岡山医学会
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File Version | publisher
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Refereed |
True
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Eprints Journal Name | joma
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