同一胃癌の大彎側と小彎側とにおける発育の差異に関する実験的研究 第1編 発育状況の肉眼的及び組織学的所見の差異について

The cancer on the side of the greater curvature of the stomach is generally benign. It is considered to owe to that the connective tissue surrounding tumor proliferates more markedly on that side than that on the lesser curvature and suppresses the growth of the cancer by enclosing. Rabbits were used for the following experiments. 1. The same amounts of Brown-Pearce tumor stocks were inoculated at the same in the greater and lesser curvatures of the same rabbit. The growth was always stronger in the lesser curvature. 2. The same amounts of foreign bodies (hard paraffin, silk thread and fluid paraffin) were enbedded or injected at the same time into the greater and lesser curvatures of the same rabbit. The proliferation of surrounding connective tissue was more marked in the greater curvature than in the lesser curvature. 3. The same amounts of Brown-Pearce tumor were inoculated at the same time into the greater and lesser curvatures. The proliferation of connctive tissue surrounding the new tumor was stronger in the greater curvature than in the lesser curvature, but the inflammatory infiltration howed no difference. 4. From the results in 1) and 3) the proliferation of the connective tissue surrounding the tumor is to be considered one of anticarcinomic reactions.