ID | 56375 |
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Author |
Makino, Takuma
Department of Otolaryngology Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Orita, Yorihisa
Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kumamoto University
Tachibana, Tomoyasu
Department of Otolaryngology, Himeji Red Cross Hospital
Marunaka, Hidenori
Department of Otolaryngology Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Miki, Kentaro
Department of Otolaryngology Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Akisada, Naoki
Department of Otolaryngology, Okayama Red Cross Hospital
Akagi, Yusuke
Department of Otolaryngology, Okayama Medical Center
Usui, Yoshiyuki
Department of Surgery, Okayama Medical Center
Sato, Yasuharu
Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Yoshino, Tadashi
Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Nishizaki, Kazunori
Department of Otolaryngology Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
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Abstract | Since no diagnostic method has been established to distinguish follicular thyroid carcinoma (FTC) from follicular thyroid adenoma (FTA), surgery has been the only way to reach a diagnosis of follicular neoplasm. Here we investigated the computed tomography (CT) features of follicular neoplasms, toward the goal of being able to identify specific CT features allowing the preoperative differentiation of FTC from FTA. We retrospectively analyzed the cases of 205 patients who underwent preoperative CT of the neck and were histopathologically diagnosed with FTC (n=31) or FTA (n=174) after surgery between January 2002 and June 2016 at several hospitals in Japan. In each of these 205 cases, non-enhanced and contrast-enhanced CT images were obtained, and we analyzed the CT features. On univariate analysis, inhomogeneous features of tumor lesions on contrast-enhanced CT were more frequently observed in FTC than in FTA (p=0.0032). A multivariate analysis identified inhomogeneous features of tumor lesions on contrast-enhanced CT images as an independent variable indicative of FTC (p=0.0023). CT thus offers diagnostic assistance in distinguishing FTC from FTA.
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Keywords | computed tomography
follicular thyroid carcinoma
follicular thyroid adenoma
preoperative diagnosis
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Amo Type | Original Article
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Publication Title |
Acta Medica Okayama
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Published Date | 2018-12
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Volume | volume72
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Issue | issue6
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Publisher | Okayama University Medical School
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Start Page | 577
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End Page | 581
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School
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File Version | publisher
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Refereed |
True
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NAID |