ID | 30726 |
JaLCDOI | |
FullText URL | |
Author |
Ogata, Masana
Kakuwa, Katsutoshi
Kondo, Yoshiro
|
Abstract | To develop a new method for evaluating the intensity of workers’ exposures to toluene alone or toluene
in mixed solvents, regression equations were calculated between the concentrations of toluene to
which workers were exposed and the concentrations of hippuric acid or toluene in workers’ urine
samples taken at the end of their shifts. Thereafter, the discriminant exposure concentration of the
solvents in air, which was the concentration considered to discriminate exposure from non-exposure
within a fi xed level of error using fi ducial ranges of individual specimens (DEC-I) or using confi dence
ranges of regression equation (DEC-R), was measured by a scale. The devised equations were applied
to calculate DEC-I or DEC-R accurately using the formulas expressing a regression line and its fi ducial
ranges or confi dence ranges. The equations can calculate not only more precise values of DEC-I
or DEC-R than can be measured by a scale, but can also calculate values corresponding to any level
of error. Moreover, DEC-I and DEC-R can be defi ned by the equations. The concentration capable
of discriminating TLV (threshold limit value) exposure from non-TLV exposure was estimated using
fi ducial ranges (DTL-I) and then using confi dence ranges of the regression equation (DTL-R).
|
Keywords | biological monitoring
exposure to toluene
discriminant exposure concentration
biomarker
urinary toluene
|
Amo Type | Original Article
|
Publication Title |
Acta Medica Okayama
|
Published Date | 2006-12
|
Volume | volume60
|
Issue | issue6
|
Publisher | Okayama University Medical School
|
Start Page | 331
|
End Page | 343
|
ISSN | 0386-300X
|
NCID | AA00508441
|
Content Type |
Journal Article
|
language |
English
|
File Version | publisher
|
Refereed |
True
|
PubMed ID | |
Web of Science KeyUT |