ID | 30381 |
JaLCDOI | |
FullText URL | |
Author |
Horiuchi, Yasuhiro
Okuno, Toshiomi
Yamanishi, Koichi
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Abstract | Examination was made of the in vitro response of human peripheral blood mononuclear cells (PBNMCs) to phytohemagglutinin (PHA) following treatment with varicella zoster virus (VZV) or herpes simplex virus type 1 (HSV 1). Cell proliferation was determined by colorimetric assay using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide. The response to PHA was depressed in all cases by virus infection of PBMNCs prior to PHA treatment. When the infection with the viruses was after PHA treatment, PHA response differed. For VZV infection, the response increased in four out of six samples, but was reduced in the other two. The response to PHA was depressed in all six samples by HSV 1 infection. |
Keywords | virus infection
nonspecific mitogen
immune response
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Amo Type | Article
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Publication Title |
Acta Medica Okayama
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Published Date | 1995-12
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Volume | volume49
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Issue | issue6
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Publisher | Okayama University Medical School
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Start Page | 309
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End Page | 312
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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File Version | publisher
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Refereed |
True
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PubMed ID | |
Web of Science KeyUT |