ID | 32364 |
JaLCDOI | |
FullText URL | |
Author |
Taketa, Kazuhisa
|
Abstract | An attempt was made to apply the method devised by ARIAS for the determination of liver glucuronyl transferase activity using 4-methyl umbelliferone as a glucuronide receptor to the small amounts of liver tissue obtained by needle biopsy. This was accomplished by studying the kinetics of enzymatic 4-methyl umbelliferone glucuronide formation by mean(of mouse liver homogenates. The improved method was proved to be applicable to human liver and gave a satisfactory result. In addition, an assay method for the estimation of liver uridine diphosphate glucuronic acid content from the amount of 4-methyl umbelliferone glucuronide formed from the uridine diphosphate glucuronic acid contained in the liver homogenate used as a source of glucuronyl transferase was studied, and as a result it was proved to be also applicable to the small amounts of human liver tissue. |
Amo Type | Article
|
Publication Title |
Acta Medicinae Okayama
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Published Date | 1962-04
|
Volume | volume16
|
Issue | issue2
|
Publisher | Okayama University Medical School
|
Start Page | 71
|
End Page | 89
|
NCID | AA00041342
|
Content Type |
Journal Article
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language |
English
|
File Version | publisher
|
Refereed |
True
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NAID |