ID | 46938 |
FullText URL | |
Author |
Kubo, Takanori
Matsuzaki, Rino
Endoh, Tamaki
Sisido, Masahiko
|
Abstract | A peptide nucleic acid (PNA)-cell-penetrating peptide (CPP) conjugate (carrier PNA) was used as 'bridgebuilder' to connect a CPP with an shRNA. The carrier PNA successfully formed a hybrid with an shRNA bearing complementary dangling bases and the shRNA was introduced into cells by the carrier PNA, and RNAi was induced by the shRNA.
|
Keywords | Peptide nucleic acid
Cell-penetrating peptide
RNA interference
|
Published Date | 2009-07-01
|
Publication Title |
Bioorganic & Medicinal Chemistry Letters
|
Volume | volume19
|
Issue | issue13
|
Publisher | Elsevier Ltd.
|
Start Page | 3410
|
End Page | 3413
|
ISSN | 0960-894X
|
NCID | AA1079577X
|
Content Type |
Journal Article
|
language |
English
|
Copyright Holders | Crown Copyright © 2009 Published by Elsevier Ltd. All rights reserved.
|
File Version | author
|
Refereed |
True
|
DOI | |
PubMed ID | |
Web of Science KeyUT |