ID | 42725 |
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Title Alternative | Experimental studies on the metabolism of erythrocytes of acatalasemia patients Report 2 The influences of various substances on the oxygen consumption of erythrocytes both in acatalasemia patients and the normal
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Author |
Yoshida, Kiyoaki
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Abstract | By examining the influences of protoporphyrin and of four kinds of metal ions, namely, those of iron, zinc, magnesium, and manganese, and the influences of glucose, lactate, glycerophosphate, acetate, pyruvate, glutamate, succinate, fumarate, malate, and aspartate, methylene blue and DPN, on the oxygen consumption of erythrocytes both in acatalasemia patients and the normal, and by further spectroscopic studies on the changes of the hemoglobin accompanying the respiration of erythrocytes when malate and aspartate of these had been used as substrates, the author reached the following conclusions: namely, in the respiration of erythrocytes of these patients as compared with the normal, no marked difference other than a comparatively weaker enzymatic action of malic dehydrogenase and the enzymes concerning aspartic acid oxidation can be recognized; and as for the disposal of small amounts of H(2)O(2) supposedly to be liberated during respiration of erythrocytes, the compensation by peroxidase, hemoglobin, or other hemin proteins may be thought to be sufficient.
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Published Date | 1957-12-31
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Publication Title |
岡山医学会雑誌
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Publication Title Alternative | Journal of Okayama Medical Association
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Volume | volume69
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Issue | issue12
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Publisher | 岡山医学会
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Publisher Alternative | Okayama Medical Association
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Start Page | 3037
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End Page | 3052
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ISSN | 0030-1558
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NCID | AN00032489
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Content Type |
Journal Article
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Official Url | https://www.jstage.jst.go.jp/article/joma1947/69/12/69_12_3037/_article/-char/ja/
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Related Url | http://www.okayama-u.ac.jp/user/oma/
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language |
Japanese
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Copyright Holders | Copyright© 岡山医学会
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File Version | publisher
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Refereed |
True
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Eprints Journal Name | joma
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