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ID 42725
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Title Alternative
Experimental studies on the metabolism of erythrocytes of acatalasemia patients Report 2 The influences of various substances on the oxygen consumption of erythrocytes both in acatalasemia patients and the normal
Author
Yoshida, Kiyoaki
Abstract
By examining the influences of protoporphyrin and of four kinds of metal ions, namely, those of iron, zinc, magnesium, and manganese, and the influences of glucose, lactate, glycerophosphate, acetate, pyruvate, glutamate, succinate, fumarate, malate, and aspartate, methylene blue and DPN, on the oxygen consumption of erythrocytes both in acatalasemia patients and the normal, and by further spectroscopic studies on the changes of the hemoglobin accompanying the respiration of erythrocytes when malate and aspartate of these had been used as substrates, the author reached the following conclusions: namely, in the respiration of erythrocytes of these patients as compared with the normal, no marked difference other than a comparatively weaker enzymatic action of malic dehydrogenase and the enzymes concerning aspartic acid oxidation can be recognized; and as for the disposal of small amounts of H(2)O(2) supposedly to be liberated during respiration of erythrocytes, the compensation by peroxidase, hemoglobin, or other hemin proteins may be thought to be sufficient.
Published Date
1957-12-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume69
Issue
issue12
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
3037
End Page
3052
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/69/12/69_12_3037/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
Copyright© 岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma