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ID 19570
Eprint ID
19570
FullText URL
Thumnail 68_1097.pdf 563 KB
Title Alternative
STUDIES ON THE WATER METABOLISM IN LIVER IMPAIRMENT. CHAPTER Ⅲ. INFLUENCES OF ADRENOCORTICAL HORMONES AND OTHER SEVERAL DRUGS ON VARIOUS BODY FLUID VOLUMES UNDER EXPERIMENTAL LIVER IMPAIRMENT
Author
Ohashi, Wataru
Abstract
The purpose of this report exists to clarify the influences of DOCA, cortisone, ACTH and glucuronic acid on the circulating plasma and blood volumes or the extracellular fluid volume in an experimental liver impairment by administering allyl formate to dogs, and the following results were obtained. 1. A subcutaneous injection of 2 mg/kg of DOCA, 20 mg/kg of cortisone or 2 International Units (I.U.)/kg. of ACTH at hour after a subcutaneous injection of allyl formate at 0.03 cc/kg, made the tendency of the decrease of the circulating plasma volume be inhibited to be genrally constant, the one of the increase of the extracellular fluid be also similarly inhibited to be finally decreased. 2. A similar injection of glucuronic acid did not influence on the circulating plasma volume or the extracellular fluid volume. 3. An intramuscular injection of 1 mg/kg of DOCA after a continuous subeutaneous injection of allyl formate at 0.01 cc/kg for 5 days, introduced a tendency to accelerate the increase of the circulating plasma volume and the extracellular fluid volume. 4. A similar intramuscular injection of cortisone at 10 mg/kg or of ACTH at 1 I.U./kg did not influence on the circulating plasma volume and the extracellular fluid volume. 5. A similar intramuscular injection of glucuronic acid at 50 mg/kg did not influence on the circculating plasma volume, while it would more or less inhibit in some cases the decrease of the extracellular fluid volume.
Published Date
1956-08-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume68
Issue
issue8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1097
End Page
1107
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/68/8/68_8_1097/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma