ID | 16279 |
Eprint ID | 16279
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FullText URL | |
Title Alternative | Helix pomatia A hemagglutinin binding activity to peripheral T-lymphocytes in malignant digestive tract diseases Part 2: Clinical studies
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Author |
Yasuhara, Takashi
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Abstract | Helix pomatia A hemagglutinin (HP) binding activity, a surface marker of peripheral T cells, to neuraminidase-treated peripheral T cells was studied in patients with digestive tract cancer or benign liver disease and in normal subjects. The HP binding activity (ng/10(6) T cells) to T cell subpopulations in peripheral lymphocytes was calculated as: (Amount of bound HP to total peripheral lymphocytes (ng/10(6) cells)) / (Ratio of T cells to total peripheral lymphocytes (%)) × 100. The calculated HP
binding activity to T cells was significantly higher in digestive tract cancer patients than in benign liver disease patients (p<0.05) and normal subjects (p<0.01). These results suggest that either the subsets of peripheral T cells with high HP binding activity may be significantly increased or HP receptors of all peripheral T cells may be increased to the same degree in digestive tract cancer patients. This activity may be a useful index of cellular immunity in digestive tract cancer patients, although it seems to have no relevance to the progression of cancer.
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Keywords | Helix pomatia A hemagglutinin
結合活性
消化器癌
末梢血T cell
neuraminidase
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Published Date | 1986-06-30
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Publication Title |
岡山医学会雑誌
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Publication Title Alternative | Journal of Okayama Medical Association
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Volume | volume98
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Issue | issue5-6
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Publisher | 岡山医学会
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Publisher Alternative | Okayama Medical Association
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Start Page | 465
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End Page | 473
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ISSN | 0030-1558
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NCID | AN00032489
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Content Type |
Journal Article
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Official Url | https://www.jstage.jst.go.jp/article/joma1947/98/5-6/98_5-6_465/_article/-char/ja/
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Related Url | http://www.okayama-u.ac.jp/user/oma/index.html
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language |
Japanese
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Copyright Holders | 岡山医学会
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File Version | publisher
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Refereed |
True
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Eprints Journal Name | joma
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