このエントリーをはてなブックマークに追加
ID 14595
Eprint ID
14595
FullText URL
Thumnail 078_445.pdf 1.56 MB
Author
Goto, Yuzo
Abstract
Skin homografting was performed on the dorsum of the left ear of adult rabbits, and the effects of cortisone and cyclophosphamide on the response of the regional lymph node were studied. The main results are briefly summarized as follows: 1) In the rabbits that received daily injections of 10 mg of cortisone, skin homograft survival was prolonged to 25.6±4.73 days, and in those treated by daily injections of 25 mg of cyclophosphamide per kilogramm of body weight to 19.5±2.02 days, as compared with the average survival time of 9.5±0.28 days in controls. With 12.5 mg of cyclophosphamide per kilogramm of body weight, only a little prolongation of skin homograft survival was observed. 2) Increase in the percentage of weight of the regional lymph node, as compared with that of contralateral node, was much lower in the cases with healthy grafts than in the cases with rejected grafts. The longer was the skin homograft survival, the greater this dlfference. 3) Even when the skin homograft survival was markedly prolonged, a slight degree of proliferative response of the regional lymph node was clearly recognized, and this is considered to be a nonspecific proliferative response of lymph node in transplantation immunity.
Note
学位番号 乙第169号
Published Date
1966-03-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume78
Issue
issue2-3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
445
End Page
450
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/78/2-3/78_2-3_445/_article/-char/ja/
Related Url
http://eprints.lib.okayama-u.ac.jp/2872/
http://eprints.lib.okayama-u.ac.jp/14591/
http://eprints.lib.okayama-u.ac.jp/14592/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma