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著者 Mizuno, Tomofumi| Nishii, Nobuhiro| Morita, Hiroshi| Ito, Hiroshi|
キーワード Transvenous pacemaker Fontan operation Sinus node dysfunction Atrial tachycardia Case report
発行日 2022-01-13
出版物タイトル European Heart Journal-Case Reports
6巻
1号
出版者 Oxford Univ Press
開始ページ ytac003
ISSN 2514-2119
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2022.
論文のバージョン publisher
PubMed ID 35059560
DOI 10.1093/ehjcr/ytac003
Web of Science KeyUT 000753349900033
関連URL isVersionOf https://doi.org/10.1093/ehjcr/ytac003
フルテキストURL fulltext20220302-1.pdf
著者 Miyoshi, Shin-ichi| Okubo, Naomi| Mitsumori, Satoko|
キーワード Surfactant Washing detergent Linear alkylbenzene sulfonate Soil bacteria
備考 This is the peer reviewed version of the following article: [Miyoshi, S, Okubo, N, Mitsumori, S. Isolation and identification of soil bacteria resistant to surfactants in washing detergents. J Surfact Deterg. 2022; 1– 5. https://doi.org/10.1002/jsde.12587], which has been published in final form at [https://doi.org/10.1002/jsde.12587]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.|
発行日 2022-02-11
出版物タイトル Journal of Surfactants and Detergents
25巻
出版者 Wiley
開始ページ 521
終了ページ 525
ISSN 1097-3958
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 AOCS.
論文のバージョン author
DOI 10.1002/jsde.12587
Web of Science KeyUT 000754169600001
関連URL isVersionOf https://doi.org/10.1002/jsde.12587
フルテキストURL fulltext20220301-2.pdf
著者 Fox, Brian|
キーワード John McGahern Irish literature Irish identity transatlantic literature America and Ireland
備考 This is an Accepted Manuscript of an article published by Taylor & Francis in Irish Studies Review on 2022-02-09, available online: http://www.tandfonline.com/10.1080/09670882.2022.2037269| This fulltext is available in Aug. 2023.|
発行日 2022-02-09
出版物タイトル Irish Studies Review
30巻
1号
出版者 Informa UK Limited
開始ページ 65
終了ページ 81
ISSN 0967-0882
NCID AA11862089
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 Informa UK Limited
論文のバージョン author
DOI 10.1080/09670882.2022.2037269
Web of Science KeyUT 000753285700001
関連URL isVersionOf https://doi.org/10.1080/09670882.2022.2037269
フルテキストURL fulltext20220301-1.pdf
著者 Tokumasu, Miho| Nishida, Mikako| Kawaguchi, Takamasa| Kudo, Ikuru| Kotani, Tohru| Takeda, Kazuhiko| Yoshida, Takao| Udono, Heiichiro|
備考 This is a pre-copyedited, author-produced version of an article accepted for publication in International Immunology following peer review. The version of record [Miho Tokumasu, Mikako Nishida, Takamasa Kawaguchi, Ikuru Kudo, Tohru Kotani, Kazuhiko Takeda, Takao Yoshida, Heiichiro Udono, Blocking EP4 downregulates tumor metabolism and synergizes with anti-PD-1 therapy to activate natural killer cells in a lung adenocarcinoma model, International Immunology, 2022;, dxac004, https://doi.org/10.1093/intimm/dxac004] is available online at: https://doi.org/10.1093/intimm/dxac004|
発行日 2022-2-8
出版物タイトル International Immunology
34巻
6号
出版者 Oxford University Press (OUP)
開始ページ 293
終了ページ 302
ISSN 1460-2377
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2022. Published by Oxford University Press on behalf of The Japanese Society for Immunology.
論文のバージョン author
DOI 10.1093/intimm/dxac004
Web of Science KeyUT 000784781800001
関連URL isVersionOf https://doi.org/10.1093/intimm/dxac004
フルテキストURL fulltext.pdf
著者 Liu, Yujia| Myojin, Takumi| Li, Kexin| Kurita, Ayuki| Seto, Masayuki| Motoyama, Ayano| Liu, Xiaoyang| Satoh, Ayano| Munemasa, Shintaro| Murata, Yoshiyuki| Nakamura, Toshiyuki| Nakamura, Yoshimasa|
キーワード 3-hydroxyphenylacetic acid aldehyde dehydrogenase quercetin metabolites aryl hydrocarbon receptor acetaldehyde
発行日 2022-02-03
出版物タイトル International Journal Of Molecular Sciences
23巻
3号
出版者 MDPI
開始ページ 1762
ISSN 1422-0067
NCID AA12038549
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 by the authors.
論文のバージョン publisher
PubMed ID 35163684
DOI 10.3390/ijms23031762
Web of Science KeyUT 000756270900001
関連URL isVersionOf https://doi.org/10.3390/ijms23031762
フルテキストURL fulltext.pdf
著者 Ando, Eri| Nakasuka, Takamasa| Kubo, Toshio| Taniguchi, Akihiko| Ninomiya, Kiichiro| Kato, Yuka| Ichihara, Eiki| Ohashi, Kadoaki| Rai, Kammei| Hotta, Katsuyuki| Yamane, Masaomi| Miyahara, Nobuaki| Tabata, Masahiro| Maeda, Yoshinobu| Kiura, Katsuyuki|
キーワード pulmonary aspergilloma allergic bronchopulmonary aspergillosis disaster
発行日 2022-02-01
出版物タイトル Internal Medicine
61巻
3号
出版者 JAPAN SOC INTERNAL MEDICINE
開始ページ 379
終了ページ 383
ISSN 0918-2918
NCID AA10827774
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 The Japanese Society of Internal Medicine
論文のバージョン publisher
PubMed ID 34373373
DOI 10.2169/internalmedicine.7124-21
Web of Science KeyUT 000752787300015
関連URL isVersionOf https://doi.org/10.2169/internalmedicine.7124-21
フルテキストURL fulltext.pdf
著者 Ishida, Tomoharu| Hagiya, Hideharu| Honda, Hiroyuki| Nakano, Yasuhiro| Ogawa, Hiroko| Obika, Mikako| Ueda, Keigo| Kataoka, Hitomi| Hanayama, Yoshihisa| Otsuka, Fumio|
発行日 2021-11-12
出版物タイトル Plos One
16巻
11号
出版者 Public Library Science
開始ページ e0259633
ISSN 1932-6203
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 Ishida et al.
論文のバージョン publisher
PubMed ID 34767587
DOI 10.1371/journal.pone.0259633
Web of Science KeyUT 000755249300037
関連URL isVersionOf https://doi.org/10.1371/journal.pone.0259633
JaLCDOI 10.18926/AMO/63222
フルテキストURL 53_3_141.pdf
著者 Nagata, Hiroshi| Ohta, Takeo| Aoyama, Hideyasu|
抄録 Medical students (fourth-year: n = 67; fifth-year: n = 63) estimated inpatients' feelings of anxiety, self-esteem, purpose-in-life, and multidimensional health locus of control. Their ratings were compared both with the ratings given by the 121 inpatients themselves and with those given by nursing practitioners (nurses and nursing students). Findings showed that the medical students overestimated inpatients' anxiety, while they underestimated the inpatients' purpose-in-life and internal health locus of control. Hence they underestimated, as did the nursing practitioners, the inpatients' positive emotional states and their positive attitude toward their own lives. Fifth-year medical students, with clinical experience, rated the inpatients' score of chance health locus of control higher than did the fourth-year medical students, who had no clinical experience. These findings indicate that medical students, like nursing practitioners, are inclined to pay more attention to inpatients' weaknesses than to their strengths.
キーワード inpatient's mental health anxiety self-esteem purpose-in-life health locus of control
Amo Type Brief Note
出版物タイトル Acta Medica Okayama
発行日 1999-06
53巻
3号
出版者 Okayama University Medical School
開始ページ 141
終了ページ 145
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 1999 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 10410792
Web of Science KeyUT 000081201100007
フルテキストURL fulltext.pdf
著者 Umebayashi, Ryoko| Uchida, Haruhito Adam| Matsuoka-Uchiyama, Natsumi| Sugiyama, Hitoshi| Wada, Jun|
キーワード chronic kidney disease medical checkup risk factor
発行日 2022-01-12
出版物タイトル Journal Of Personalized Medicine
12巻
1号
出版者 MDPI
開始ページ 97
ISSN 2075-4426
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 by the authors.
論文のバージョン publisher
PubMed ID 35055412
DOI 10.3390/jpm12010097
Web of Science KeyUT 000757349900001
関連URL isVersionOf https://doi.org/10.3390/jpm12010097
JaLCDOI 10.18926/AMO/63219
フルテキストURL 76_1_99.pdf
著者 Naito, Yoichiro| Yoshikawa, Masaki| Nakamura, Kazufumi| Kubo, Motoki| Sugiyama, Hiroyasu| Suzuki, Hideyuki| Fujita, Shinpei| Arai, Yasunori| Takahashi, Sho| Kato, Yuichi| Yoshida, Yu| Akai, Hiroaki| Murakami, Shuhei| Ito, Hiroshi|
抄録 Rapidly progressive in-stent restenosis (ISR) after stent deployment from the left main trunk (LMT) to the left anterior descending artery (LAD) without plaque at the LMT ostium has not been reported. A 60-year-old Japanese man with a history of scleroderma, pulmonary fibrosis, and type 2 diabetes developed acute myocardial infarction of the right coronary artery (RCA) and was treated by emergency percutaneous coronary intervention (PCI) for RCA. Nine days later he underwent PCI from the LMT to the LAD. Follow-up coronary angiography (CAG) at 9 and 21 months post-PCI did not reveal ISR in any lesion, but the patient experienced cardiac arrest at 25 months post-PCI. Emergency CAG after resuscitation revealed ISR of the LMT ostium; emergency PCI was conducted. The development of ISR at the ostium of the LMT although the patient was free of plaque 4 months before is extremely unusual. This rare ISR of the LMT ostium progressed rapidly after follow-up CAG revealed no ISR at 21 months post-stent implantation.
キーワード left main trunk in-stent restenosis cardiopulmonary arrest
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2022-02
76巻
1号
出版者 Okayama University Medical School
開始ページ 99
終了ページ 104
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 35237006
Web of Science KeyUT 000762933000003
JaLCDOI 10.18926/AMO/63218
フルテキストURL 76_1_93.pdf
著者 Ishi, Yukitomo| Yamaguchi, Shigeru| Hatanaka, Kanako C.| Takakuwa, Emi| Motegi, Hiroaki| Honda, Taishi| Kobayashi, Hiroyuki| Terasaka, Shunsuke| Homma, Akihiro| Fujimura, Miki| Houkin, Kiyohiro|
抄録 A 66-year-old man underwent multimodal treatment for olfactory neuroblastoma (ONB). When he was 72 years old, a cystic intracranial lesion without accumulation on fluorine-18-fluorodeoxyglucose positron emission tomography was detected. Surgical resection was performed when the patient was 73 years old. The pathological examination revealed recurrence of ONB, and the patient underwent focal irradiation. At age 81, he presented with a second recurrence in the right occipital lobe with radiological and pathological findings similar to the prior recurrence. This case suggests that pathological confirmation should be considered in cases with atypical radiological findings following the treatment of ONB.
キーワード cystic recurrence esthesioneuroblastoma fluorine-18-fluorodeoxyglucose positron emission tomography intracranial recurrence olfactory neuroblastoma
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2022-02
76巻
1号
出版者 Okayama University Medical School
開始ページ 93
終了ページ 98
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 35237005
Web of Science KeyUT 000762933000002
JaLCDOI 10.18926/AMO/63217
フルテキストURL 76_1_89.pdf
著者 Ryuko, Tsuyoshi| Yamamoto, Hiromasa| Sugimoto, Seiichiro| Suzawa, Ken| Miyoshi, Kentaroh| Otani, Shinji| Okazaki, Mikio| Yamane, Masaomi| Toyooka, Shinichi|
抄録 Congenital lobar emphysema (CLE) is defined as the hyperinflation of pulmonary lobes due to obstruction of the flow of air via a known or unknown etiology, which causes pressure symptoms in the adjacent organs. CLE is mainly diagnosed in the neonatal period, and very few adult cases have been reported. Here we report a 34-year-old male with muscular dystrophy who was diagnosed with CLE on examination. He underwent a right lower lobectomy via 3-portal completely video-assisted thoracoscopic surgery, and his symptoms improved. Thoracoscopic surgery helped preserve the respiratory muscles and led to the improvement of respiratory function in this patient.
キーワード congenital lobar emphysema, adult, lobectomy, completely video-assisted thoracoscopic surgery, muscular dystrophy
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2022-02
76巻
1号
出版者 Okayama University Medical School
開始ページ 89
終了ページ 92
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 35237004
Web of Science KeyUT 000762933000001
JaLCDOI 10.18926/AMO/63216
フルテキストURL 76_1_85.pdf
著者 Omi, Hirotsugu| Tomita, Takashi| Ichinohe, Masayuki| Harada, Yoshifumi| Sato, Hideki| Ito, Junji|
抄録 A 75-year-old woman underwent L4-L5 lateral interbody fusion for L4-5 foraminal stenosis with the use of percutaneous pedicle screws. On the day after the surgery, she was in shock. Emergency contrast-enhanced CT showed active extravasation from the 4th lumbar artery with a transverse process fracture. A radiologist performed a successful transarterial embolization, and the patient then began walking training on the 4th day post-surgery. Close attention should be paid to the insertion of a percutaneous pedicle screw, as it may cause a lumbar artery injury; in such a case, transarterial embolization is the preferred treatment.
キーワード lumbar artery injury percutaneous pedicle screw transverse process fracture hematoma
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2022-02
76巻
1号
出版者 Okayama University Medical School
開始ページ 85
終了ページ 88
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 35237003
Web of Science KeyUT 000762803800003
JaLCDOI 10.18926/AMO/63215
フルテキストURL 76_1_79.pdf
著者 Tokumoto, Kana| Mino, Takuya| Kurosaki, Yoko| Izumi, Koji| Maekawa, Kenji| Nakano, Tomohito| Sejima, Junichi| Ueda, Akihiro| Kimura-Ono, Aya| Hyung Kim, Tae| Kuboki, Takuo|
抄録 We introduce a new digital workflow to fabricate a fixed partial denture (FPD) utilizing the three-dimensional surface morphology of provisional restoration (PR) and abutment teeth. Scanned images of the full maxilla with abutment teeth, full maxilla with PR, and PR alone were superimposed. The surfaces of the final FPD were designed based on the entire morphology of the PR and abutment teeth surfaces. The inner and outer surfaces converged at the margin lines of the abutment teeth. Fine modifications to the final FPD design were performed manually, and the final FPD was fabricated and successfully installed in the patient.
キーワード prosthodontics computer-aided design digital dentistry fixed partial denture dental restoration
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2022-02
76巻
1号
出版者 Okayama University Medical School
開始ページ 79
終了ページ 84
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 35237002
Web of Science KeyUT 000762803800002
JaLCDOI 10.18926/AMO/63214
フルテキストURL 76_1_71.pdf
著者 Tanaka, Masato| Sonawane, Sumeet| Fujiwara, Yoshihiro| Uotani, Koji| Arataki, Shinya| Yamauchi, Taro| Ye, Youchen| Misawa, Haruo|
抄録 The surgical treatment of pediatric atlantoaxial subluxation (AAS) in Down syndrome (DS) remains technically challenging due to radiation exposure and complications such as vertebral artery injury and nonunion. The established treatment is fixation with a C1 lateral mass screw and C2 pedicle screw (modified Goel technique). However, this technique requires fluoroscopy for C1 screw insertion. To avoid exposing the operating team to radiation we present here a new C-arm free O-arm navigated surgical procedure for pediatric AAS in DS. A 5-year-old male DS patient had neck pain and unsteady gait. Radiograms showed AAS with an atlantodental interval of 10 mm, and irreducible subluxation on extension. CT scan showed Os odontoideum and AAS. MRI demonstrated spinal cord compression between the C1 posterior arch and odontoid process. We performed a C-arm free O-arm navigated modified Goel procedure with postoperative halo-vest immobilization. At oneyear follow-up, good neurological recovery and solid bone fusion were observed. The patient had no complications such as epidural hematoma, infection, or nerve or vessel injury. This novel procedure is a useful and safe technique that protects surgeons and staff from radiation risk.
キーワード atlantoaxial fixation Down syndrome C-arm free O-arm navigation surgery modified Goel technique
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2022-02
76巻
1号
出版者 Okayama University Medical School
開始ページ 71
終了ページ 78
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 35237001
Web of Science KeyUT 000762803800001
JaLCDOI 10.18926/AMO/63213
フルテキストURL 76_1_63.pdf
著者 Zhang, Bei| Pei, Zhixin| Wang, Hongxia| Wu, Huimin| Wang, Junjie| Bai, Junjun| Song, Qinglin|
抄録 We analyzed the treatment effects of chidamide and decitabine in combination with a HAG (homoharringtonine, cytarabine, G-CSF) priming regimen (CDHAG) in acute myeloid leukemia (AML) patients with TP53 mutation. Seven TP53 mutated AML patients were treated with CDHAG. The treatment effects were assessed using hemogram detection and bone marrow aspirate. The possible side effects were evaluated based on both hematological and non-hematological toxicity. Four of the seven patients were classified as having achieved complete remission after CDHAG treatment; one patient was considered to have achieved partial remission, and the remaining two patients were considered in non-remission. The overall response rate (ORR) to CDHAG was 71.4%. Regarding the side effects, the hematological toxicity level of the seven patients ranged from level III to level IV, and infections that occurred at lung, blood, and skin were recorded. Nausea, vomiting, liver injury, and kidney injury were also detected. However, all side effects were attenuated by proper management. The CDHAG regimen clearly improved the ORR (71.4%) of TP53-mutated AML patients, with no severe side effects.
キーワード acute myeloid leukemia chidamide decitabine HAG TP53 mutation
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2022-02
76巻
1号
出版者 Okayama University Medical School
開始ページ 63
終了ページ 70
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 35237000
Web of Science KeyUT 000762812700009
JaLCDOI 10.18926/AMO/63212
フルテキストURL 76_1_57.pdf
著者 Iguchi, Toshihiro| Hiraki, Takao| Matsui, Yusuke| Toji, Tomohiro| Uka, Mayu| Tomita, Koji| Komaki, Toshiyuki| Umakoshi, Noriyuki| Mitsuhashi, Toshiharu| Kanazawa, Susumu|
抄録 To evaluate the volume and heat-sink effects of microwave ablation (MWA) in the ablation zone of the normal swine lung. MWA at 100 W was performed for 1, 2, and 3 min in 7, 5, and 5 lung zones, respectively. We assessed the histopathology in the ablation zones and other outcome measures: namely, length of the longest long and short axes, sphericity, ellipsoid area, and ellipsoid volume. The mean long- and short-axis diameters were 22.0 and 14.1 mm in the 1-min ablation zone, 27.6 and 20.2 mm in the 2-min ablation zone; and 29.2 and 21.2 mm in the 3-min ablation zone, respectively. All measures, except sphericity, were significantly less with 1-min ablation than with either 2- or 3-min ablation. There were no significant differences between the 2- and 3-min ablation zones, but all measures except sphericity were larger with 3-min ablation. Although there were no blood vessels that resulted in a heat-sink effect within the ablation zones, the presence of bronchi nearby in 5 lung ablation zones resulted in reduced ablation size. In high-power, short-duration MWA, the lung ablation volume was affected by ablation time. Some ablations showed that a heat-sink effect by a neighboring bronchus might occur.
キーワード microwave ablation lung ablation zone heat-sink effect swine
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2022-02
76巻
1号
出版者 Okayama University Medical School
開始ページ 57
終了ページ 62
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 35236999
Web of Science KeyUT 000762812700008
フルテキストURL fulltext20220222-2.pdf
著者 Kawashima, Takeshi| Yoshida, Masa-aki| Miyazawa, Hideyuki| Nakano, Hiroaki| Nakano, Natumi| Sakamoto, Tatsuya| Hamada, Mayuko|
キーワード eDNA marine invertebrate Xenacoelomorpha Acoela Praesagittifera naikaiensis Placozoa Trichoplax adhaerens
備考 This fulltext is published by Zoological Society of Japan. To access the final published work, see https://doi.org/10.2108/zs210073 .| This full-text file will be available in Feb. 2023.|
発行日 2022-01-28
出版物タイトル Zoological Science
39巻
1号
出版者 Zoological Society of Japan
開始ページ 157
終了ページ 165
ISSN 0289-0003
NCID AA10545874
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 Zoological Society of Japan
論文のバージョン publisher
PubMed ID 35107003
DOI 10.2108/zs210073
Web of Science KeyUT 000752098100015
関連URL isVersionOf https://doi.org/10.2108/zs210073
フルテキストURL fulltext20220222-1.pdf SI20220222-1.pdf
著者 Okamoto, Ryuichi| Koga, Kenichiro|
備考 This document is the Accepted Manuscript version of a Published Work that appeared in final form in The Journal of Physical Chemistry B, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.jpcb.1c08050 .|
発行日 2021-11-10
出版物タイトル The Journal of Physical Chemistry B
125巻
46号
出版者 American Chemical Society (ACS)
開始ページ 12820
終了ページ 12831
ISSN 1520-6106
NCID AA11114073
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 American Chemical Society
論文のバージョン author
PubMed ID 34756051
DOI 10.1021/acs.jpcb.1c08050
Web of Science KeyUT 000750898200015
関連URL isVersionOf https://doi.org/10.1021/acs.jpcb.1c08050
JaLCDOI 10.18926/AMO/63209
フルテキストURL 76_1_51.pdf
著者 Eto, Eriko| Tani, Kazumasa| Maki, Jota| Hayata, Kei| Masuyama, Hisashi|
抄録 Polycystic ovary syndrome (PCOS) is a common endocrine metabolic disorder that is associated with high insulin resistance and obesity. However, ~70% of women with PCOS in Japan are non-obese. We retrospectively analyzed the cases of 163 Japanese women with PCOS who visited our Ob/Gyn department in 2006-2018 to determine which has a greater effect on insulin resistance: PCOS or obesity. We reviewed the women’s medical records and calculated their insulin resistance and insulin secretion. The women’s mean age and pre-pregnancy body mass index (BMI) were 30±5.8 years and 24.8±5.6 kg/m2, respectively; their mean ± SD fasting plasma glucose, 94.1±13.7 mg/dL; HOMA-IR, 2.1±2.0; QUICKI, 0.4±0.0; and HOMA-β, 108.9±88.0%. Sixtyeight women were pregnant, and 37% (n=25) were obese (BMI ≥ 25 kg/m2). Obesity had a greater effect on insulin resistance: fasting plasma glucose F(1, 53)=6.134, p<0.05; fasting insulin F(1, 53)=31.606, p<0.01; HOMA-IR F(1, 53)=31.670, p<0.01; QUICKI F(1, 53)=16.156, p<0.01. There was no significant difference in values other than QUICKI and testosterone between the women with and without PCOS. Obesity thus had a greater effect on increased insulin resistance in pregnant women with PCOS. Further studies of the insulin resistance of non-obese women with PCOS is needed, as non-obese women with PCOS are common in Asia.
キーワード polycystic ovary syndrome insulin resistance obesity pregnancy
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2022-02
76巻
1号
出版者 Okayama University Medical School
開始ページ 51
終了ページ 56
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 35236998
Web of Science KeyUT 000762812700007