検索結果 981 件
著者 | 出宮 通孝| |
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発行日 | 1988 |
出版物タイトル | 岡山医学会雑誌 |
巻 | 100巻 |
号 | 1-2号 |
資料タイプ | 学術雑誌論文 |
JaLCDOI | 10.18926/15824 |
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フルテキストURL | Mem_Sch_Eng_OU_17_1_97.pdf |
著者 | Oda Kiichi| Yoshio Tetsuo| O-oka Kazuo| |
抄録 | A series of ferroelectric glass-ceramics was elaborated by the controlled growth of Ba(1-x)Sr(x)TiO(3) crystal particles in the glass system 60[Ba(1-y)Sr(y)]TiO(3)-10Al(2)O(3)-30SiO(2)(0≦y≦0.2) in molar basis. Analysis of crystal phases by X-ray diffraction revealed that Sr content in Ba(1-x)Sr(x)TiO(3) increased with increasing content of SrO in glasses by its preferential transfer into the crystal phase, and the appropriate temperature for the crystal growth was 1100°C. Curie temperatures of glass -ceramics shifted to lower temperature with increasing SrO content in the crystal and comparatively high dielectric constant was obtained at room temperature for a glass-ceramics with y=0.2. Frequency dependences of dielectric constant and loss tangent were examined in the frequency range from 1 K to 1 M Hz. |
出版物タイトル | Memoirs of the School of Engineering, Okayama University |
発行日 | 1983-02-25 |
巻 | 17巻 |
号 | 1号 |
開始ページ | 97 |
終了ページ | 105 |
ISSN | 0475-0071 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307890 |
JaLCDOI | 10.18926/15772 |
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フルテキストURL | Mem_Sch_Eng_OU_15_2_55.pdf |
著者 | Hida Moritaka| Matsumori Nobuo| Terauchi Hikaru| |
抄録 | X-ray diffuse scatteing intensity measurement has been carried out for the Al-3,82% Cu single crystal in which GP (2) zones are found. The two dimensional equiintensity contour maps in h(1) h(2) 0 plane are obtained from surveying around several reflections. The diffuse intensity around 2 1 0 reflection, which shows a cross like streak, is carefully examined. Warren-Cowley short-range order parameters, a(i), are estimated from the diffuse intensities around 2 1 0 reflection. The component of the intensities coming from atomic displacements was subtracted from the total diffuse intensity. It is found that the equi-intensity contours after the correction of the atomic displacements shows an anisotropic distribution and the GP(2) zone is an ellipsoid with a modified layer structure. |
出版物タイトル | Memoirs of the School of Engineering, Okayama University |
発行日 | 1981-03-30 |
巻 | 15巻 |
号 | 2号 |
開始ページ | 55 |
終了ページ | 67 |
ISSN | 0475-0071 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307124 |
JaLCDOI | 10.18926/15765 |
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フルテキストURL | Mem_Sch_Eng_OU_15_1_111.pdf |
著者 | Korenaga Takashi| Ikatsu Hisayoshi| Moriwake Tosio| Takahashi Teruo| |
抄録 | On the flow injection analysis (FIA) of chemical oxygen demand (COD), silver salt was added as an oxidation catalyst for COD substances and a masking agent for halide to improve operating conditions of the FIA apparatus. Both of a proper concentration of potassium permanganate solution and 6.0 % sulfuric acid solution containing 0.1 % silver nitrate are individually pumped up with respective flow rates of 0.51 ml min(-l) and merged into a carrier stream. A 20 μ1 of sample solution is injected into the flow of sulfuric acid solution at just before the merging place. The sample mixed with the carrier solutions in a reaction manifol(polytetrafluoroethylene tubing: 0.5 mm i.d. x 30 m), is passed through a thermostated bath at 100 °c and led to a flow cell for the absorbance measurements at 525 nm. The absorbances are continuously recorded with time. The peaks in the recordings showed good reproducibility and the calibration obtained at a linear concentration range of 0 - 170 mg 1(-1) COD with glucose as standard. The detection limit and precision confirmed with this method were 5 mg 1(-1) and 0.8 %, respectively. Chloride ion up to 200 mg 1(-1) did not interfere without elimination of a silver chloride precipitate. By the present FIA method, several industrial waste water samples were analyzed at a sampling rate of about 40 samples per hour, and their apparent COD values were compared with those found by the manual JIS method. Both of the methods gave the similar results within an error range from -35 to +5 %. |
出版物タイトル | Memoirs of the School of Engineering, Okayama University |
発行日 | 1980-11-29 |
巻 | 15巻 |
号 | 1号 |
開始ページ | 111 |
終了ページ | 121 |
ISSN | 0475-0071 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307490 |
JaLCDOI | 10.18926/15740 |
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フルテキストURL | Mem_Sch_Eng_OU_14_1_55.pdf |
著者 | 古賀 隆治| Hirao, Keiji| Kosaka, Megumi| Sano, Hiroya| |
抄録 | An absorption spectrum of γ-0 band of nitric monoxide of very dilute density was taken. An experimental electronic device showed a distinguishing power of 0.01 ppm through 10 m optical pathlength. By the aid of a data processing based on a principle developed by the authors, this sensitivity does not suffer from coexisting sulfur dioxide, which shares the absorption band with the nitric monoxide. |
出版物タイトル | Memoirs of the School of Engineering, Okayama University |
発行日 | 1979-12-01 |
巻 | 14巻 |
号 | 1号 |
開始ページ | 55 |
終了ページ | 60 |
ISSN | 0475-0071 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307855 |
JaLCDOI | 10.18926/15717 |
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フルテキストURL | Mem_Sch_Eng_OU_13_153.pdf |
著者 | Fukui, Kiyoshi| Nogi, Shigeji| Yamada, Masuo| Sakakibara, Akira| |
抄録 | A unified treatment of injection and mutual phase locking phenomena in microwave oscillators coupled by a network characterized by a Y-matrix is presented. Under certain simplifying assumptions, steady state solutions such as locking frequency and oscillation phase relation are given with emphasis placed on the coupling-network dependence of locking bandwidth. Also, some examples of locking system specified by y(21)=0, Y(21)= Y(12) and y21= -Y12 are briefly discussed. |
出版物タイトル | Memoirs of the School of Engineering, Okayama University |
発行日 | 1979-03-05 |
巻 | 13巻 |
開始ページ | 153 |
終了ページ | 162 |
ISSN | 0475-0071 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307532 |
JaLCDOI | 10.18926/15712 |
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フルテキストURL | Mem_Sch_Eng_OU_13_119.pdf |
著者 | Ohta, Mutsuo| Yamada, Masuo| Kanadani, Teruto| 榊原 精| |
抄録 | The effects of the fluctuation of solute concentration on the process of aging in Al-10wt % Zn alloy were studied by measurements of the intensity of small-angle X-ray scattering and by electron microscopy. Specimen was quenched from a higher temperature(T(Ql), mainly 300℃) to an intermediate temperature (T(Q2), 110~230℃), held there for a time, quenched again into iced water and aged isothermally at 0℃ or 40℃. Results obtained are as follows: (1) When the specimen was held at T(Q2) for a sufficient time and aged at relatively high temperatue(e.g. Ihr at 125℃ and aged at 40℃), a two-step increasing of both resistivity and integrated intensity was found. (2) Each of the steps has characteristics of the formation of G.P. zones by the spinodal decomposition. (3) When the maximum resistivity(p(max)) takes a minimum, Size distribution of the G.P. zones, estimated from the difference between Guinier and Porod radii, is much broader than that at p(max) in the usual direct quenching. (4) When the holding time at T(Q2) is long enough, the size distribution at p(max) is as broad as that at p(max) in the usual case. (5) After a prolonged aging under the condition that P(max) takes minimum, G.P. zones grow markedly and become oblate ellipsoidal with a major axis of about 20nm. (6) These results are consistently understood in terms of the fluctuation of solute concentration at T(Q2) and the change in the concentration of vacancies during annealing at T(Q2). That is, it is considered that these results are due to the difference in aging behavior between the regions of relatively high concentration and the ones of low concentration induced by the fluctuation. |
出版物タイトル | Memoirs of the School of Engineering, Okayama University |
発行日 | 1979-03-05 |
巻 | 13巻 |
開始ページ | 119 |
終了ページ | 132 |
ISSN | 0475-0071 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307931 |
JaLCDOI | 10.18926/15639 |
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フルテキストURL | Mem_Sch_Eng_OU_6_47.pdf |
著者 | Takahashi Katsuaki| Goto Yasumasa| |
抄録 | The glass forming limit by substitution of CdS for CdO in a CdO-B(2)0(3) glass was determined by chemical analysis. When x CdS-(60-x)CdO-40B(2)0(3) nominal mixtures in weight ratio were heated at 1100°C in flowing nitrogen gas for 1/2 hour, about 40~50% of mixed CdS and 10-15% of the mixed CdS were evaporated. The limit of nominal composition for glass forming was 10CdS-50CdO-40B(2)0(3) and the corresponding virtual composition after the above heat treatment was found to be 4.9CdS-46.4CdO-48.7B(2)O(3). Further addition of CdS made the melt devitrefied with CdS precipitation. D.C. conductivity measurements revealed that the current density was not linear with respect to the applied voltage, but the resistivity ranged around 10(12)Ω・cm for 4.1CdS-48.8CdO-47.1B(2)O(3) (virtual composition) glass and around 10(11.5)Ω·cm for 4.9CdS-46.4CdO-48.7B(2)O(3) glass. These sulphur containing glasses did not show photoconduction, although CdS-precipitated materials showed slight photoconductivity when disposed in ultra violet radiation. Apparent dielectric constant and tan 8 were also measured as a function of frequency, revealing a moderate dispersion in the CdS-precipitated glasses. |
出版物タイトル | Memoirs of the School of Engineering, Okayama University |
発行日 | 1971-09-01 |
巻 | 6巻 |
号 | 1号 |
開始ページ | 47 |
終了ページ | 52 |
ISSN | 0475-0071 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307147 |
JaLCDOI | 10.18926/15439 |
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フルテキストURL | Mem_Fac_Eng_OU_26_2_77.pdf |
著者 | 和田 修己| Nakajima Masamitsu| |
抄録 | This paper describes a method to design an antenna to focus millimeter-wave beam generated by a gyrotron. The antenna, which has been proposed by the authors, consists of a stair-cut circular waveguide and two cylindrical reflectors; one is elliptic and the other is parabolic. Its principle is based on the geometrical optics though slightly modified to consider the diffraction effect. Results of low-power experiments agree well with the design on beam direction, beam width and the position of the focal point. At 35.5 GHz using TE(01) mode, a focused beam with half-power thickness of 13 mm x 10 mm was obtained. This type of antennas find applications to millimeter-wave scattering measurement in fusion plasma research and high- energy-density source for material heating. |
出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
発行日 | 1992-03-28 |
巻 | 26巻 |
号 | 2号 |
開始ページ | 77 |
終了ページ | 92 |
ISSN | 0475-0071 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307321 |
JaLCDOI | 10.18926/15365 |
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フルテキストURL | Mem_Fac_Eng_OU_30_1_1.pdf |
著者 | Dong Liu| 梶原 康博| 大崎 紘一| 宗澤 良臣| |
抄録 | A method for standardizing parts is proposed. This method aims to reduce the sort of parts for cutting the manufacturing cost and for improving specifications of parts. Two linear mathematical programming models are proposed for standardizing the parts. One model aims at cutting cost half without causing any degradation of mechanical specifications of parts. The other model aims at doubling mechanical specifications of parts below the acceptable manufacturing cost. These models are formulated in 0-1 integer programming forms. The integer programming model shows which part is common to other parts. An example is shown to demonstrate the use of the developed method. |
出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
発行日 | 1995-12-28 |
巻 | 30巻 |
号 | 1号 |
開始ページ | 1 |
終了ページ | 7 |
ISSN | 0475-0071 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307491 |
JaLCDOI | 10.18926/15345 |
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タイトル(別表記) | 気管支喘息の発症における加齢の影響について |
フルテキストURL | 063_142_147.pdf |
著者 | 光延 文裕| 貴谷 光| 岡崎 守宏| 御舩 尚志| 谷崎 勝朗| |
抄録 | Skin tests, serum total IgE levels, specific IgE antibodies against each allergen, bronchial reactions provoked by allergens and histamine release from basophils are well known as prameters of immediate allergic reactions. The incidence of positive immediate skin reaction to allergens such as house dust, ragweed, Aspergillus Alternaria, Cladosporium and Broncasma decreased with aging. On the other hand, the incidence of positive skin reaction to Candida albicans was higher in cases between the age of 41 and 50 and cases over the age of 61 compared to that in the other groups classified by age. Serum IgE levels was highest in cases aged between 0 and 30. The levels of serum IgE decreased with aging. The incidence of positive RAST scores (more than 2+) and positive bronchial reaction to house dust were highest in cases between 0 and 30, and decreased with aging. However, the positive ratio of these tests against C. albicans were highest in cases between 41 and 50. The degree of histamine release from basophils of asthmatics induced by anti-IgE was consistently high without any correlation to aging when their serum IgE levels were more than 501 IU/ml. In the cases with serum IgE levels of less than 300 IU/ml, basophil reactivity to anti-IgE decreasd with aging. Basophil reactivity to house dust was generally dependent on the levels of specific IgE antibodies against the allergen. Although basophil reactivity to C. albicans was also high in cases with positive RAST scores, some cases with a RAST score of 0+ or 1+ showed high or moderate basophil reactivity. Moderate or high reactivity of basophils was frequently observed in cases between 41 and 50 and cases over age 61. |
キーワード | Skin test (皮内反応) IgE Provocation test (吸入誘発試験) Basophil reactivity (好塩基球の反応性) Aging (加齢) |
出版物タイトル | 岡大三朝分院研究報告 |
発行日 | 1992-06 |
巻 | 63巻 |
開始ページ | 142 |
終了ページ | 147 |
ISSN | 0913-3771 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307130 |
JaLCDOI | 10.18926/15337 |
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タイトル(別表記) | Pathogenic significance of IgG and IgG(4) antibodies against Candida albicans in bronchial asthma |
フルテキストURL | 064_116_124.pdf |
著者 | 谷崎 勝朗| 貴谷 光| 御舩 尚志| 光延 文裕| 梶本 和宏| 杉本 啓介| |
抄録 | カレジダ特異的IgG及びIgG(4)抗体が,気管支喘息の発症病態に関与しているかどうかについて検討を加えた。カンジダ特異的IgGおよびIgG(4)抗体は, 0-30才の年齢層の症例ではアトピー性素因の強い症例で,また,31-60才の年齢層の症例ではストロイド依存性重症難治性喘息症例で,さらに61才以上の高年令の症例で,その産生亢進が観察される。これらの症例におけるIgG及びIgG(4)抗体産生は,0-30才の年齢ではアトピーとの関連で,また31-60才の年齢では副腎皮質ホルモンの長期投与と関連して,さらに61才以上の症例では加齢と関連して,細胞性免疫能が低下し,そのためカンジダの発育が促進され,その結果として,IgG及びIgG(4)抗体の産生亢進が見られることが明らかにされている。すなわち,気管支喘息におけるカンジダに対するIgG系抗体の産生亢進は,cell-mediated immunityの低下と言う共通の基盤を有しており,病因的意義とは必ずしも関連していないことを述べた。 |
キーワード | カンジダ (Candida) lgG抗体 (IgG antibodies) IgG(4)抗体 (IgG(4) antibodies) アトピー (Atopy) 気管支喘息 (Bronchial asthma) |
出版物タイトル | 岡大三朝分院研究報告 |
発行日 | 1993-06 |
巻 | 64巻 |
開始ページ | 116 |
終了ページ | 124 |
ISSN | 0918-7839 |
言語 | 日本語 |
論文のバージョン | publisher |
NAID | 120002307381 |
JaLCDOI | 10.18926/15325 |
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タイトル(別表記) | 気管支喘息患者における細胞性免疫,ガンジダ抗原に対する遅延型反応の抑制 |
フルテキストURL | 063_069_073.pdf |
著者 | 谷崎 勝朗| 貴谷 光| 岡崎 守宏| 御舩 尚志| 光延 文裕| 原田 英雄| 越智 浩二| 木村 郁郎| |
抄録 | Delayed cutaneous hypersensitivity towards Candida albicans was examined in 200 patients with bronchial asthma in relation to patient age and the level of total IgE. 1. Delayed skin reactivity towards C.albicans was depressed in the patients between the ages of 10 and 20 and in those over the age of 61. A significant difference was present in delayed skin reactivity between the groups of 10-20 and 41-50 years old. 2. The frequency of the patients with positive delayed skin reactivity towards C.albicans was the highest in those with low levels of total IgE (0 -100 IU/ml) and the low est in those with high levels of total IgE (over than 1001 IU/ml). The results suggest that cell-mediated immunity towards C.albicans is depressed re lating to atopics in the patients between 10 and 20 and to aging in the patients over 61. |
キーワード | cell-mediated immunity (細胞性免疫) bronchial asthma (気管支喘息) atopics (アトピー) aging (加齢) カンジダ |
出版物タイトル | 岡大三朝分院研究報告 |
発行日 | 1992-06 |
巻 | 63巻 |
開始ページ | 69 |
終了ページ | 73 |
ISSN | 0913-3771 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307949 |
JaLCDOI | 10.18926/15324 |
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タイトル(別表記) | 臨床所見および検査成績からのスコアーによる喘息分類の特徴 |
フルテキストURL | 063_063_068.pdf |
著者 | 谷崎 勝朗| 貴谷 光| 岡崎 守宏| 御舩 尚志| 光延 文裕| 谷水 将邦| 本家 尚子| 草浦 康浩| 高取 明正| 奥田 博之| 木村 郁郎| |
抄録 | Twenty six patients with bronchial asthma was classified by clinical symptoms and singns (clinical diagnosis), and the classification by clinical diagnosis was compared with the classification by a score calculated from clinical findings and examinations (score diagnosis). 1. Of 12 subjects with type Ia classified by clinical diagnosis, 8 cases with 0 to 49 ml/day of expectoration were evaluated as type Ia by score diagnosis. While four type Ia cases with 50 to 99ml/day of expectoration were calssified as type Ib by score diagnosis. The increased incidence of eosinophils in bronchoalveolar lavage fluid (BALF) of these four cases was similar to the incidence in type Ib cases with hypersecretion. 2. All of 6 subjects with type Ib by clinical diagnosis were estimated as type Ib by score diagnosis. 3. Of 8 cases with type II by clinical diagnosis, 7 cases were assessed as type II by score diagnosis. One case with type II by clinical diagnosis and with the score of 10 points was evaluated as questionable type II by score diagnosis. |
キーワード | asthma classification (喘息分類) bronchoconstriction (気管支攣縮) hypersecretion (過分泌) bronchiolar obstruction (細気管支閉塞) score diagnosis (スコアー診断) |
出版物タイトル | 岡大三朝分院研究報告 |
発行日 | 1992-06 |
巻 | 63巻 |
開始ページ | 63 |
終了ページ | 68 |
ISSN | 0913-3771 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307348 |
JaLCDOI | 10.18926/15316 |
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タイトル(別表記) | 老年者の気管支喘息. アレルギー反応と気道細胞反応 |
フルテキストURL | 063_039_043.pdf |
著者 | 谷崎 勝朗| 貴谷 光| 岡崎 守宏| 御舩 尚志| 光延 文裕| 谷水 将邦| 本家 尚子| 草浦 康浩| 越智 浩二| 原田 英雄| 木村 郁郎| |
抄録 | Clinical features of bronchial asthma in the elderly were analyzed by observlng IgE-mediated allerglc reactions evaluated by immediate skin reaction and specific IgE antibodies to allergens, ventilatory function and cellular composition in bronchoalveolar lavage (BAL) fluid. 1. The frequency of positive immediate skin reaction and positive RAST score to allergens was in general low in the elderly patients over age 70. 2. Ventilatory function was widely variegated, and fifteen cases (60%) of the 25 Subjects showed considerably high values of FEV(l.0%), % PEFR, % MMF, % V(50) and % V(25), and the mean value of FEV(1.0%) in these cases was 71.3%. 3. The decreased value of % V(25) was related to BAL neutrophilia in 2 cases, but any correlation was not found between BAL neutrophilia and decreased value of % V(25) in 9 csese of the eleven subjects who had the BAL examination. The results show that in asthma of elderly patients, IgE-mediated allergic reactions are weak, and that a decreased value of % V(25) can be observed without BAL neutrophilia. |
キーワード | elderly subjects (老年者) lgE-mediated allergic reaction (IgE系反応) ventilatory function (換気機能) BAL neutrophilia (BAL好中球) bronchial asthma (気管支喘息) |
出版物タイトル | 岡大三朝分院研究報告 |
発行日 | 1992-06 |
巻 | 63巻 |
開始ページ | 39 |
終了ページ | 43 |
ISSN | 0913-3771 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307727 |
著者 | 岡山大学医療技術短期大学部| |
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発行日 | 1997-09-10 |
出版物タイトル | 岡山大学医療技術短期大学部紀要 |
巻 | 8巻 |
号 | 1号 |
資料タイプ | その他 |
JaLCDOI | 10.18926/15229 |
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タイトル(別表記) | 加温後のtsAF8細胞の細胞周期 |
フルテキストURL | 012_2_101_106.pdf |
著者 | 澁谷 光一| 川崎 祥二| 黒田 昌宏| 浅海 淳一| 加藤 博和| 平木 祥夫| |
抄録 | Thermotolerance in tsAF8 cells develops during incubation at 34℃ after heating at 45℃, while it is suppressed by the following incubation at a non-permissive temperature of 39.7℃ after the same heating. The incubation temperature after heating may affect the cell cycle and consequently thermotolerance. In the present study, a relationship between the thermotolerance and the cell cycle of tsAF8 was investigated. The cell cycle fractions and DNA synthesis were measured by flow cytometry using double staining with propidium iodide and bromodeoxyuridine. When the tsAF8 cells were heated at 45℃ for 20 min, and thereafter incubated at 34℃, bromodeoxyuridine uptake in the S phase cells (DNA synthesis) was recovered to 65.1% 6 h after the heating, and the cells showed gradual accumulation in the G(2)/M phase. When the cells were incubated at 39.7℃ after heating at 45℃ for 20 min, then showed inhibition of thermotolerance development, the DNA synthesis was recovered to 15.1% temporarily 6 h after the heating, but it became 0% after 12 h, and the cells did not remarkably accumulate in any phases of the cell cycle. This inhibition of DNA synthesis at 39.7℃ was considered to be the result of cell survival decreasing by a step-down heating. However, the relationship between the thermotolerance and the cell cycle was not found out in tsAF8 cells, because the cells did not accumulate in any phases of the cell cycle under the inhibitory condition of thermotolerance. |
キーワード | thermotolerance (温熱耐性) hyperthermia (ハイパーサーミア) tsAF8 cell cycle (細胞周期) |
出版物タイトル | 岡山大学医学部保健学科紀要 |
発行日 | 2002-03-20 |
巻 | 12巻 |
号 | 2号 |
開始ページ | 101 |
終了ページ | 106 |
ISSN | 1345-0948 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307264 |
JaLCDOI | 10.18926/15121 |
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タイトル(別表記) | 気管支喘息患者の血清コーチゾール値について. 副腎皮質ホルモン投与および年齢との関連 |
フルテキストURL | 066_030_036.pdf |
著者 | 保﨑 泰弘| 御舩 尚志| 光延 文裕| 梶本 和宏| 横田 聡| 谷崎 勝朗| 越智 浩二| 原田 英雄| 池田 敏| 武田 和久| |
抄録 | Serum cortisol levels were examined in 94 patients with bronchial asthma in relation to dose of glucocorticoids and age. 1. The level of serum cortisol was significantly lower in group A patients, treated with glucocorticoids (prednisolone of 5mg/day or more) for more than 2 years, (2.4±1.2mcg/㎗) than in group B, treated with glucocorticoids (prednisolone of 5mg or less) for less than 2 years, (6.8±3.7mcg/㎗) (p<0.001) and in group C, treated without glucocorticoids, (12.6±3.9mcg/㎗) (p<0.001). The serum cortisol level was also significantly lower in group B than in group C (p<0.001). 2. The level of serum cortisol was significantly lower in patients over the age of 70 compared to that in those aged between 0 and 39 years (p<0.01) and those between 40 and 49 (p<0.05), and those between 50 and 59 (p<0.02). The level was also lower in patients between 60 and 69 compared to that in those between 0 and 39, however, this was not significant. These results demonstrate that the level of serum cortisol decreases by long-term glucocorticoid regimen and with aging. |
キーワード | serum cortisol level (血清コーチゾール) bronchial asthma (気管支喘息) clinical asthma type (臨床病型) glucocorticoids (副腎皮質ホルモン) aging (加齢) |
出版物タイトル | 岡大三朝分院研究報告 |
発行日 | 1995-09 |
巻 | 66巻 |
開始ページ | 30 |
終了ページ | 36 |
ISSN | 0918-7839 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307345 |
JaLCDOI | 10.18926/15119 |
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タイトル(別表記) | 気管支喘息患者の気管支肺胞細胞からのヒスタミンとロイコトリエンC4遊離 ―アトピー性喘息におけるヒスタミンの役割について― |
フルテキストURL | 066_014_020.pdf |
著者 | 光延 文裕| 御舩 尚志| 梶本 和宏| 保﨑 泰弘| 横田 聡| 谷崎 勝朗| 越智 浩二| 原田 英雄| |
抄録 | To clarify the main humoral triggering factor (histamine and/or leukotriene) of the early stage of asthma attacks, the release of histamine and leukotriene C4 (LTC4) from bronchoalveolar lavage (BAL) cells stimulated with Ca ionophore A23187 was examined in 7 patients with atopic asthma, and the results were compared to those in 7 nonatopic asthma patients. 1. The proportion of BAL basophilic cells was significantly higher in atopic patients than in nonatopic patients (p<0.05). 2. The content of histamine in BAL fluid was significantly higher in atopic (2.3mcg/mℓ) comparted to that in nonatopic patients (0mcg/mℓ)(p<0.001). The content of LTC4 was high in nonatopic (2.4ng/mℓ) than in atopic patients (0.5ng/ mℓ), however, this was not significant. 3. The release of histamine from BAL cells was 32.6% in atopic and 0% in nonatopic patients, and this was significant (p<0.001). The release of LTC4 from BAL cells was significantly higher in nonatopic (11.3ng/10(6)cell) than in atopic (3.5ng/10(6)cell)(p<0.02). The results demonstrate that histamine play more important role in atopic patients as a main triggering factor of attacks than LTC4. In contrast, in nonatopic patients, LTC4 is more predominant than histamine during early stage of asthma attacks. |
キーワード | Histamine LTC4 BAL cells atopic asthma |
出版物タイトル | 岡大三朝分院研究報告 |
発行日 | 1995-09 |
巻 | 66巻 |
開始ページ | 14 |
終了ページ | 20 |
ISSN | 0918-7839 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307251 |
JaLCDOI | 10.18926/15117 |
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タイトル(別表記) | ダニ喘息における気道遊走細胞からのヒスタミン遊離の加齢による減少 |
フルテキストURL | 066_001_007.pdf |
著者 | 谷崎 勝朗| 御舩 尚志| 光延 文裕| 梶本 和宏| 保﨑 泰弘| 横田 聡| 越智 浩二| 原田 英雄| 池田 敏| 武田 和久| |
抄録 | Histamine release from bronchoalveolar cells induced by house dust mite (HDm) was compared in patients with atopic asthma sensitive to HDm in relation to age. 1. Total cell number in bronchoalveolar lavage (BAL) fluid was larger in patients over the age of 40 years (9.10×10(6)) than in those aged between 20 and 39 years (6.25×10(6)), however, this was not significant. 2. Number of BAL eosinophils was not significantly different between the two age groups. 3. Number of BAL basophilic cells was significantly higher in younger patients (20-39 years) (1.85±1.03×10(2)/mℓ) than in older patients (40+ years) (0.39±0.24×10(2)/mℓ) (p<0.001). 4. Histamine release from BAL cells induced by HDm was significantly higher in younger patients (38.1±24.8%) than in older patients (0%) (p<0.001). These results suggest that histamine release from BAL cells in patients with HDm allergy decreases with aging. |
キーワード | Bronchial asthma House dust allergy Histamine release Bronchoalveolar cells |
出版物タイトル | 岡大三朝分院研究報告 |
発行日 | 1995-09 |
巻 | 66巻 |
開始ページ | 1 |
終了ページ | 7 |
ISSN | 0918-7839 |
言語 | 英語 |
論文のバージョン | publisher |
NAID | 120002307845 |