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JaLCDOI 10.18926/ESR/56691
タイトル(別表記) Non-calcareous beachrock found in Akagurisaki, Ohi Town, Fukui Prefecture
フルテキストURL esr_025_001_005.pdf
著者 鈴木 茂之| 東 洋一| 出山 康代| 湯川 弘一| 臼井 まゆみ|
抄録 Beachrock which was formed about 0.5 meter higher than high tide is found in Akagurisaki, Ohi Town, Fukui Prefecture. The outcrops always get wet by spring water. The sediments are composed of well sorted rounded gravels and sands but calcareous shell is not found at all. Intergranular space is occupied by white amorphous cement. Magnesium and silicon rich composition of the cement is obtained by EPMA analysis. There is a conjecture that the magnesium rich cement was precipitated in spite of solution of calcareous shell under saturated state by spring water, because calcium has a higher tendency to ionize than magnesium.
キーワード Beachrock Akagurisaki non-calcareous cement ionization tendency
出版物タイトル Okayama University Earth Science Report
発行日 2018-12-27
25巻
1号
開始ページ 1
終了ページ 5
ISSN 1340-7414
言語 日本語
著作権者 © 2018 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
論文のバージョン publisher
JaLCDOI 10.18926/ESR/56189
タイトル(別表記) Rounded pebble of metamorphosed iron-formations from conglomerate of the Miocene deposits in Yatakayama, Kibi Plateau, Okayama Prefecture
フルテキストURL esr_024_1_001_004.pdf
著者 鈴木 茂之| 小網, 晴男| 臼井, まゆみ|
抄録 The Kibi Plateau was a part of the Eurasian Continent and separated by the event of opening of Japan Sea. The rounded pebble which is considered to be continental origin was discovered. The pebble is siliceous and attracts magnets. Prepared thin-sections were observed under microscope. Selected minerals were analyzed by EPMA. The rock is composed of recrystallized quartz, magnetite, riebeckite, stilpnomelane and associated with very tiny minerals with very high relief and interference colors. The assemblage suggests that there is a possibility that the rock is a metamorphic rock of iron-formations and derived from continent.
キーワード Continental origin Miocene conglomerate rounded pebble iron-formations Kibi Plateau
出版物タイトル Okayama University Earth Science Report
発行日 2017-12-27
24巻
1号
開始ページ 1
終了ページ 4
ISSN 1340-7414
言語 日本語
著作権者 © 2017 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
論文のバージョン publisher
タイトル(別表記) A case of mucinous adenocarcinoma of the duodenum and literature review of 16 cases reported in Japan
フルテキストURL 128_21.pdf
著者 浜野 郁美| 松本 祐介| 遠藤 芳克| 渡邊 直樹| 甲斐 恭平| 佐藤 四三| 和仁 洋治|
抄録  Primary mucinous adenocarcinoma of the duodenum is rare. Here we report a case we recently encountered, and we review 16 cases reported in Japan. An 82-year-old Japanese woman was admitted to our hospital complaining of abdominal pain and heartburn. An endoscopic examination revealed a Type 2 tumor in the descending limb of the duodenum, and endoscopically obtained specimens revealed a poorly differentiated adenocarcinoma. We performed a curative pancreatoduodenectomy with lymph node resection, and the surgical specimen revealed that the duodenum was the primary site of the mucinous adenocarcinoma. The patient is currently alive > 1 year after the operation without any evidence of recurrence. Of the 16 patients reviewed, all patients had advanced tumors those depth were T3-T4. 9 patients had lymph node metastasis and 4 patients had peritoneal dissemination at the time of surgery. Since mucinous adenocarcinoma of the duodenum is often progressive cancer at a diagnosis, which is tend to have a worse prognosis than other histological types.
キーワード 原発性十二指腸癌(primary duodenal cancer) 粘液癌(mucinous carcinoma) 膵頭十二指腸切除(pancreatoduodenectomy)
出版物タイトル 岡山医学会雑誌
発行日 2016-04-01
128巻
1号
開始ページ 21
終了ページ 25
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.128.21
言語 日本語
著作権者 Copyright (c) 2016 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.128.21
NAID 130005149602
タイトル(別表記) A case report of giant ectopic pheochromocytoma conversion therapy with radioisotope therapy and chemotherapy followed by curative resection
フルテキストURL 127_213.pdf
著者 安井 和也| 楳田 祐三| 熊野 健二郎| 田端 雅弘| 大塚 文男| 八木 孝仁| 藤原 俊義|
抄録 A 46-year-old man was found to be positive for occult blood at a medical checkup and was revealed to have a 14-cm tumor on the right side of abdominal aorta by a subsequent abdominal CT scan. The endocrinology laboratory data showed elevations in the levels of serum noradrenaline, and ectopic pheochromocytoma was suspected. The tumor was compressing the inferior vena cava and portal vein, the superior mesenteric artery and the pancreas. Since it would be difficult to cure by operation, neoadjuvant therapy was started using radioisotope therapy by I-131 metaiodobenzylguanidine (131I-MIBG) and chemotherapy (CVD therapy ; cyclophosphamide, vincristine, dacarbazine). He was treated with three courses of radioisotope therapy and 16 courses of chemotherapy, which significantly reduced the tumor size. This made radical resection possible ; we were able to avoid the merger excision of great vessels and other organs. On pathological and immunopathological findings, the tumor was diagnosed as ectopic pheochromocytoma. Regarding the safety and curability of the treatment, neoadjuvant therapy may be useful in treating very large tumors that show invasion of other organs.
キーワード 異所性褐色細胞腫(ectopic pheochromocytoma) 化学療法(chemo therapy) 131I-MIBG
出版物タイトル 岡山医学会雑誌
発行日 2015-12-01
127巻
3号
開始ページ 213
終了ページ 218
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.213
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.213
NAID 130005116814
タイトル(別表記) Hospital and clinic cooperation for the treatment of rheumatoid arthritis in Okayama Prefecture, Japan
フルテキストURL 126_209.pdf
著者 佐田 憲映| 西田 圭一郎| 山中 隆夫| 三崎 健太| 若林 宏| 篠田 潤子| 髙木 徹| 矢野 隆介| 中村 明彦| 難波 良文| 守田 吉孝| 小山 芳伸| 山本 惠嗣| 江澤 和彦| 太田 裕介| 吉原 由樹| 三好 信也| 棗田 将光| 臼井 正明| 吉永 泰彦| 林 充| 山村 昌弘| 橋詰 博行|
抄録 Objective: To survey the current status and problems of cooperation between clinics and hospitals in Okayama Prefecture, Japan for the treatment of rheumatoid arthritis (RA).  Methods: We distributed a questionnaire to 300 of the 983 Okayama Prefecture clinics that had either an internal medicine or orthopedic surgery department, from December 2013 to February 2014. The questionnaire covered practice pattern for RA treatment in clinics, current status of the hospital and clinic cooperation, and acceptance of the biologic therapy.  Results: One hundred clinics responded to the questionnaire. Seventy percent of the clinics reported making referrals to rheumatologists before the initiation of RA treatment, and half of the other 30% of the clinics administered methotrexate as the first-line treatment for RA by their own decision. Sixty-six clinics cooperated with flagship hospitals, conducting medical and laboratory examinations, providing prescriptions, and treating common diseases of patients. These clinics expected the cooperating rheumatologists to follow-up patients every 3 to 6 months and to make the diagnosis, make decisions regarding RA treatment changes, and perform surgery. Seventy-one percent of the clinics responded that cooperation with a hospital is possible even for patients who are administered biologics. As reasons for no cooperation with the flagship hospitals, clinics noted the lack of information about rheumatologists in the area and recent trends in the management of RA.  Conclusion: The current study reported, for the first time, the actual conditions of management of RA in clinics, as well as future problems of hospital and clinic cooperation in Okayama Prefecture.
キーワード 病診連携(hospital and clinic cooperation) 関節リウマチ(rheumatoid arthritis) 生物学的製剤(biologics) メトトレキサート(methotrexate)
出版物タイトル 岡山医学会雑誌
発行日 2014-12-01
126巻
3号
開始ページ 209
終了ページ 215
ISSN 0030-1558
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.209
NAID 130004903246
JaLCDOI 10.18926/AMO/50406
フルテキストURL 67_3_135.pdf
著者 Ueno, Hiroshi| Shoshi, Chikafumi| Suemitsu, Shunsuke| Usui, Shinichi| Sujiura, Hiroko| Okamoto, Motoi|
抄録 In the phenomenon known as cross-modal plasticity, the loss of one sensory system is followed by improved functioning of other intact sensory systems. MRI and functional MRI studies suggested a role of the prefrontal cortex and the temporal lobe in cross-modal plasticity. We used a mouse model to examine the effects of sensory deprivation achieved by whisker trimming and visual deprivation achieved by dark rearing in neonatal mice on the appearance of parvalbumin (PV) neurons and the formation of glutamic acid decarboxylase 67 (GAD67)-positive puncta around pyramidal neurons in the prefrontal cortex and hippocampus. Whisker trimming, but not dark rearing, decreased the density of PV neurons in the hippocampus at postnatal day 28 (P28). In the prefrontal cortex, whisker trimming and dark rearing decreased the density of PV neurons in layer 5/6 (L5/6) at P28 and in L2/3 at P56, respectively, whereas dark rearing increased the density of PV neurons in L5/6 at P56. Whisker trimming decreased the density of GAD67-positive puncta in CA1 of the hippocampus at both P28 and P56 and in L5/6 of the prefrontal cortex at P28. Dark rearing decreased the density of GAD67-positive puncta in CA1 of the hippocampus and in both L2/3 and L5/6 of the prefrontal cortex at P28, and in L2/3 of the prefrontal cortex at P56. These results demonstrate that somatosensory or visual deprivation causes changes in the PV-interneuronal network in the mouse prefrontal cortex and hippocampus. The results also suggest that the alteration of the PV-interneuronal network, especially in the prefrontal cortex, may contribute to cross-modal plasticity.
キーワード sensory deprivation parvalbumin glutamate decarboxylase (GAD67) prefrontal cortex hippocampus
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2013-06
67巻
3号
出版者 Okayama University Medical School
開始ページ 135
終了ページ 143
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 23804136
Web of Science KeyUT 000320747900002
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/50870
JaLCDOI 10.18926/AMO/48264
フルテキストURL 66_2_143.pdf.pdf
著者 Watanabe, Makiko| Ueno, Hiroshi| Suemitsu, Shunsuke| Yokobayashi, Eriko| Matsumoto, Yosuke| Usui, Shinichi| Sujiura, Hiroko| Okamoto, Motoi|
抄録 Recent studies have demonstrated the important role of immune molecules in the development of neuronal circuitry and synaptic plasticity. We have detected the presence of FcγRllB protein in parvalbumin- containing inhibitory interneurons (PV neurons). In the present study, we examined the appearance of PV neurons in the barrel cortex and the effect of sensory deprivation in FcγRllB-deficient mice (FcγRllB-/-) and wild-type mice. There was no substantial difference in the appearance of PV neurons in the developing barrel cortex between FcγRllB-/- and wild-type mice. Sensory deprivation from immediately after birth (P0) or P7 to P12-P14 induced an increase in PV neurons. In contrast, sensory deprivation from P7 or P14 to P28, but not from P21 to P28, decreased PV neurons in wild-type mice. However, sensory deprivation from P0 or P7 to P12-P14 did not increase PV neurons and sensory deprivation from P7 or P14 to P28 did not decrease or only modestly decreased PV neurons in FcγRllB-/- mice. The results indicate that expression of PV is regulated by sensory experience and the second and third postnatal weeks are a sensitive period for sensory deprivation, and suggest that FcγRllB contributes to sensory experience-regulated expression of PV.
キーワード parvalbumin fast-spiking interneurons FcγRllB barrel cortex sensory deprivation
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2012-04
66巻
2号
出版者 Okayama University Medical School
開始ページ 143
終了ページ 154
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2012 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22525472
Web of Science KeyUT 000303175300007
著者 Matsuura, Hiroko| Murakami, Takashi| Hina, Kazuyoshi| Yamamoto, Keizo| Kawamura, Hiroshi| Sogo, Taiji| Shinohata, Ryoko| Usui, Shinichi| Ninomiya, Yoshifumi| Kusachi, Shozo|
発行日 2008-02
出版物タイトル Clinical Biochemistry
41巻
3号
資料タイプ 学術雑誌論文
著者 臼井 隆|
発行日 1985-10-30
出版物タイトル 岡山医学会雑誌
97巻
9-10号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/15190
タイトル(別表記) The effect of Coicis semen and Rhizopus oligosporus-fermented Coicis semen (tempeh) on serum cholesterol in the rat
フルテキストURL 015_1_009_014.pdf
著者 岡本 基| 臼井 真一| 岡崎 三代|
抄録 はとむぎ(Coicis semen)をテンペ菌(Rhizopus oligosporus)で発酵したはとむぎテンペ(テンペ)の血清コレステロール代謝に対する作用を検討した。生後12週齢のSprague-Dawley系雄ラットに市販固形飼料(コントロール群),はとむぎ混合飼料(はとむぎ群),テンペ混合飼料(テンペ群)を投与し,2,6,18週間後に高速液体クロマトグラフィー法で血清コレステロールを測定した。体重増加,総コレステロールはいずれの時点でも3群間に差がなかったが,テンペ群では投与前と比較して2,6,18週間後にLDLコレステロールが有意に低下し,LDLコレステロール/HDLコレステロール比も2,18週間後に有意に低下した。テンペ群はコントロール群と比較してもLDLコレステロールとLDLコレステロール/HDLコレステロール比が低く,はとむぎ群でも低い傾向がみられたが,有意差はなかった。以上から,テンペがコレステロール代謝改善作用をもつことが示唆された。
キーワード はとむぎ (Coicis semen) はとむぎテンペ (Rhizopus oligosporus, tempeh) コレステロール (cholesterol) ラット (rat)
出版物タイトル 岡山大学医学部保健学科紀要
発行日 2004-12-15
15巻
1号
開始ページ 9
終了ページ 14
ISSN 1345-0948
言語 日本語
論文のバージョン publisher
NAID 120002307933
著者 臼井 隆|
発行日 2009-08-03
出版物タイトル 岡山医学会雑誌
121巻
2号
資料タイプ 一般雑誌記事
著者 臼井 正明|
発行日 1992
出版物タイトル 岡山医学会雑誌
104巻
3-4号
資料タイプ 学術雑誌論文
著者 長田 建|
発行日 1994
出版物タイトル 岡山医学会雑誌
106巻
3-4号
資料タイプ 学術雑誌論文
著者 森 泰胤| 高島 均| 瀬尾 裕之| 大川 元臣| 田邉 正忠| 山本 剛禧|
発行日 1993-08
出版物タイトル 岡山医学会雑誌
105巻
7-8号
資料タイプ 学術雑誌論文
著者 石井 泰則| 井上 文之| 伴 秀利| 上川 康明| 折田 薫三|
発行日 1994-08
出版物タイトル 岡山医学会雑誌
106巻
7-8号
資料タイプ 学術雑誌論文
著者 倉地 克直|
発行日 2003
出版物タイトル 文化共生学研究
1巻
1号
資料タイプ 紀要論文
JaLCDOI 10.18926/8852
著者 臼井 洋輔|
発行日 2000-03-25
出版物タイトル
資料タイプ 学位論文
著者 臼井 隆|
発行日 1985-12-31
出版物タイトル
資料タイプ 学位論文
著者 臼井 裕子|
発行日 1986-12-31
出版物タイトル
資料タイプ 学位論文