検索結果 - 岡山大学学術成果リポジトリ

Effect of a Cyclooxygenase-2 Inhibitor in Combination with (−)-Epigallocatechin Gallate or Polyphenon E on Cisplatin-Induced Lung Tumorigenesis in A/J Mice

JaLCDOI	10.18926/AMO/64363
フルテキストURL	77_1_65.pdf
著者	Sato, Ken\| Takigawa, Nagio\| Kubo, Toshio\| Katayama, Hideki\| Kishino, Daizo\| Okada, Toshiaki\| Hisamoto, Akiko\| Mimoto, Junko\| Ochi, Nobuaki\| Yoshino, Tadashi\| Ueoka, Hiroshi\| Tanimoto, Mitsune\| Maeda, Yoshionobu\| Kiura, Katsuyuki\|
抄録	We investigated the effects of celecoxib combined with (−)-epigallocatechin-3-gallate (EGCG) or polyphenon E in a cisplatin-induced lung tumorigenesis model. Four-week-old female A/J mice were divided into seven groups: (i) Control, (ii) 150 mg/kg celecoxib (150Cel), (iii) 1,500 mg/kg celecoxib (1500Cel), (iv) EGCG+150 mg/kg celecoxib (EGCG+150Cel), (v) EGCG+1,500 mg/kg celecoxib (EGCG+1500Cel), (vi) polyphenon E+150 mg/kg celecoxib (PolyE+150Cel), and (vii) polyphenon E+1,500 mg/kg celecoxib (PolyE+1500Cel). All mice were administered cisplatin (1.62 mg/kg of body weight, i.p.) 1×/week for 10 weeks and sacrificed at week 30; the numbers of tumors on the lung surface were then determined. The tumor incidence and multiplicity (no. of tumors/mouse, mean±SD) were respectively 95% and 2.15±1.50 in Control, 95% and 2.10±1.29 in 150Cel, 86% and 1.67±1.20 in 1500Cel, 71% and 1.38±1.24 in EGCG+150Cel, 67% and 1.29±1.38 in EGCG+1500Cel, 80% and 1.95±1.36 in PolyE+150Cel, and 65% and 1.05±0.10 in PolyE+1500Cel. The combination of high-dose celecoxib with EGCG or polyphenon E significantly reduced multiplicity in cisplatin-induced lung tumors.
キーワード	celecoxib cisplatin EGCG lung tumor polyphenon E
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-02
巻	77巻
号	1号
出版者	Okayama University Medical School
開始ページ	65
終了ページ	70
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	36849147
Web of Science KeyUT	000952992100004

Increased Glycine-conjugated and Unconjugated Bile Acid Levels Associated with Aggravation of Nonalcoholic Steatohepatitis and Cardiovascular Disease in SHRSP5/Dmcr Rat

JaLCDOI	10.18926/AMO/64358
フルテキストURL	77_1_29.pdf
著者	Yamamoto, Shusei\| Sato, Ikumi\| Fujii, Moe\| Kakimoto, Mai\| Honma, Koki\| Akiyama, Natsumi\| Sakai, Miku\| Fukuhama, Natsuki\| Kumazaki, Shota\| Hirohata, Satoshi\| Kitamori, Kazuya\| Yamori, Yukio\| Watanabe, Shogo\|
抄録	The SHRSP5/Dmcr is a useful animal model for the development of nonalcoholic steatohepatitis (NASH) pathology when fed a high-fat, high-cholesterol diet, and further drug interventions can lead to concomitant cardiovascular disease. While SHRSP5/Dmcr rats have been used for basic research related to NASH, details of their bile acid metabolism in this condition are unknown. In this study, we aimed to clarify the changes in the serum bile acid (BA) fractions associated with NASH and found that glycine-conjugated and unconjugated bile acid increased with worsening NASH and cardiovascular disease while taurine-conjugated BA relatively decreased.
キーワード	SHRSP5/Dmc nonalcoholic steatohepatitis cardiovascular disease glycine-conjugated bile acids unconjugated bile acids
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-02
巻	77巻
号	1号
出版者	Okayama University Medical School
開始ページ	29
終了ページ	36
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	36849143
Web of Science KeyUT	000953019200001

Surgical Techniques of Gastrojejunostomy in Robotic Pancreatoduodenectomy: Robot-Sewn versus Stapled Gastrojejunostomy Anastomosis

フルテキストURL	fulltext.pdf
著者	Takagi, Kosei\| Umeda, Yuzo\| Yoshida, Ryuichi\| Fuji, Tomokazu\| Yasui, Kazuya\| Kimura, Jiro\| Hata, Nanako\| Yagi, Takahito\| Fujiwara, Toshiyoshi\|
キーワード	pancreatoduodenectomy robotic surgery gastrojejunostomy delayed gastric emptying
発行日	2023-01-16
出版物タイトル	Journal Of Clinical Medicine
巻	12巻
号	2号
出版者	MDPI
開始ページ	732
ISSN	2077-0383
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 by the authors.
論文のバージョン	publisher
PubMed ID	36675661
DOI	10.3390/jcm12020732
Web of Science KeyUT	000914818600001
関連URL	isVersionOf https://doi.org/10.3390/jcm12020732

Multiple White Plaques in the Esophagus: A Possible Case of Esophageal Mucosal Alteration Associated With Immune-Related Adverse Events of Immune Checkpoint Inhibitors

フルテキストURL	fulltext.pdf
著者	Iwamuro, Masaya\| Tanaka, Takehiro\| Kono, Yoshiyasu\| Kawano, Seiji\| Okada, Horoyuki\|
キーワード	nivolumab ipilimumab immune -related adverse events immune checkpoint inhibitor esophagogastroduodenoscopy
発行日	2022-12-19
出版物タイトル	CUREUS JOURNAL OF MEDICAL SCIENCE
巻	14巻
号	12号
出版者	Cureus
開始ページ	e32710
ISSN	2168-8184
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Iwamuro et al.
論文のバージョン	publisher
PubMed ID	36686096
DOI	10.7759/cureus.32710
Web of Science KeyUT	000905471200003
関連URL	isVersionOf https://doi.org/10.7759/cureus.32710

Zinc Acetate Dihydrate Tablet-Associated Gastritis Occurring in a Post-Hematopoietic Stem Cell Transplant Recipient

フルテキストURL	fulltext.pdf
著者	Iwamuro, Masaya\| Tanaka, Takehiro\| Matsumura, Akifumi\| Kawano, Seiji\| Kawahara, Yoshiro\| Okada, Hiroyuki\|
発行日	2022-12-31
出版物タイトル	Case Reports In Gastrointestinal Medicine
巻	2022巻
出版者	Hindawi Ltd
開始ページ	4637707
ISSN	2090-6528
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Masaya Iwamuro et al.
論文のバージョン	publisher
PubMed ID	36624891
DOI	10.1155/2022/4637707
Web of Science KeyUT	000910999400001
関連URL	isVersionOf https://doi.org/10.1155/2022/4637707

Effects of Helicobacter pylori and Nitrate-Reducing Bacteria Coculture on Cells

フルテキストURL	fulltext.pdf
著者	Ojima, Hinako\| Kuraoka, Sakiko\| Okanoue, Shyoutarou\| Okada, Hiroyuki\| Gotoh, Kazuyoshi\| Matsushita, Osamu\| Watanabe, Akari\| Yokota, Kenji\|
キーワード	Helicobacter pylori nitrate-reducing bacteria IL-8 TNF-alpha cell cycle
発行日	2022-12-16
出版物タイトル	Microorganisms
巻	10巻
号	12号
出版者	MDPI
開始ページ	2495
ISSN	2076-2607
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	36557748
DOI	10.3390/microorganisms10122495
Web of Science KeyUT	000903731600001
関連URL	isVersionOf https://doi.org/10.3390/microorganisms10122495

Endoscopic ablation therapy for the pancreatic neoplasms

フルテキストURL	fulltext20230110-1.pdf Table1_20230110-1.pdf Table2_20230110-1.pdf Table3_20230110-1.pdf Table4_20230110-1.pdf Figure 1A.jpg Figure 1B.jpg Figure 1C.jpg Figure 1D.jpg Figure 1E.jpg Figure 1F.jpg
著者	Matsumoto, Kazuyuki\| Kato, Hironari\|
キーワード	ablation techniques endoscopic ultrasonography ethanol pancreatic neoplasms radiofrequency ablation
備考	This is the peer reviewed version of the following article: [Matsumoto, K. and Kato, H. (2023), Endoscopic ablation therapy for the pancreatic neoplasms. Digestive Endoscopy. https://doi.org/10.1111/den.14468], which has been published in final form at [https://doi.org/10.1111/den.14468]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\| This full-text file will be available in Dec. 2023.\|
発行日	2022-12-13
出版物タイトル	Digestive Endoscopy
巻	35巻
号	4号
出版者	Wiley
開始ページ	430
終了ページ	442
ISSN	0915-5635
NCID	AA10907137
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Japan Gastroenterological Endoscopy Society.
論文のバージョン	author
PubMed ID	36366955
DOI	10.1111/den.14468
Web of Science KeyUT	000897965200001
関連URL	isVersionOf https://doi.org/10.1111/den.14468

Endoscopic treatment for duodenal perforation due to biliary stent dislocation: A case report and brief review of the literature

フルテキストURL	fulltext.pdf
著者	Fujii, Yuki\| Matsumoto, Kazuyuki\| Miyamoto, Kazuya\| Matsumi, Akihiro\| Morimoto, Kosaku\| Terasawa, Hiroyuki\| Yamazaki, Tatsuhiro\| Horiguchi, Shigeru\| Tsutsumi, Koichiro\| Kato, Hironari\|
キーワード	biliary stent endoscope migration perforation
発行日	2022-12-02
出版物タイトル	MEDICINE
巻	101巻
号	48号
出版者	LIPPINCOTT WILLIAMS & WILKINS
開始ページ	e31868
ISSN	0025-7974
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 the Author(s).
論文のバージョン	publisher
PubMed ID	36482637
DOI	10.1097/MD.0000000000031868
Web of Science KeyUT	000895502600121
関連URL	isVersionOf https://doi.org/10.1097/MD.0000000000031868

Surgical Strategies to Dissect around the Superior Mesenteric Artery in Robotic Pancreatoduodenectomy

フルテキストURL	fulltext.pdf
著者	Takagi, Kosei\| Umeda, Yuzo\| Yoshida, Ryuichi\| Fuji, Tomokazu\| Yasui, Kazuya\| Kimura, Jiro\| Hata, Nanako\| Mishima, Kento\| Yagi, Takahito\| Fujiwara, Toshiyoshi\|
キーワード	robotic surgery pancreatoduodenectomy surgical approach superior mesenteric artery pancreatic cancer
発行日	2022-11-30
出版物タイトル	Journal Of Clinical Medicine
巻	11巻
号	23号
出版者	MDPI
開始ページ	7112
ISSN	2077-0383
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	36498684
DOI	10.3390/jcm11237112
Web of Science KeyUT	000896167800001
関連URL	isVersionOf https://doi.org/10.3390/jcm11237112

Clinical implications and optimal extent of lymphadenectomy for intrahepatic cholangiocarcinoma: A multicenter analysis of the therapeutic index

フルテキストURL	fulltext.pdf
著者	Umeda, Yuzo\| Takagi, Kosei\| Matsuda, Tatsuo\| Fuji, Tomokazu\| Kojima, Toru\| Satoh, Daisuke\| Hioki, Masayoshi\| Endo, Yoshikatsu\| Inagaki, Masaru\| Oishi, Masahiro\| Yagi, Takahito\| Fujiwara, Toshiyoshi\|
キーワード	intrahepatic cholangiocarcinoma lymphadenectomy multicenter study retrospective study
発行日	2022-11-27
出版物タイトル	Annals Of Gastroenterological Surgery
出版者	Wiley
ISSN	2475-0328
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Authors.
論文のバージョン	publisher
DOI	10.1002/ags3.12642
Web of Science KeyUT	000891179400001
関連URL	isVersionOf https://doi.org/10.1002/ags3.12642

Study Protocol for a Trial: A Single-Arm, Open-Labeled Study Evaluating Transcatheter Arterial Embolization Plus Everolimus Combination Therapy for Patients With Liver Metastasis of Gastroenteropancreatic Neuroendocrine Tumors

フルテキストURL	fulltext.pdf
著者	Takeuchi, Yasuto\| Kato, Hironari\| Horiguchi, Shigeru\| Oyama, Atsushi\| Adachi, Takuya\| Wada, Nozomu\| Onishi, Hideki\| Shiraha, Hidenori\| Takaki, Akinobu\|
キーワード	NETs TAE clinical trial
発行日	2022
出版物タイトル	Clinical Medicine Insights－Oncology
巻	16巻
出版者	Sage Publications Ltd.
開始ページ	1
終了ページ	5
ISSN	1179-5549
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
PubMed ID	36387610
DOI	10.1177/11795549221127750
Web of Science KeyUT	000888437000001
関連URL	isVersionOf https://doi.org/10.1177/11795549221127750

Involvement in the tumor-infiltrating CD8(+) T cell expression by the initial disease of remnant gastric cancer

フルテキストURL	fulltext.pdf
著者	Kakiuchi, Yoshihiko\| Kikuchi, Satoru\| Kuroda, Shinji\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
キーワード	Remnant gastric cancer Prognostic factor Tumor-infiltrating lymphocytes CD8(+) T cell Tumor immunity
発行日	2022-11-30
出版物タイトル	World Journal Of Surgical Oncology
巻	20巻
号	1号
出版者	BMC
開始ページ	374
ISSN	1477-7819
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022.
論文のバージョン	publisher
PubMed ID	36451224
DOI	10.1186/s12957-022-02853-2
Web of Science KeyUT	000892980100002
関連URL	isVersionOf https://doi.org/10.1186/s12957-022-02853-2

Oncolytic virus-mediated reducing of myeloid-derived suppressor cells enhances the efficacy of PD-L1 blockade in gemcitabine-resistant pancreatic cancer

フルテキストURL	fulltext20221215-1.pdf figures20221215-1.pdf Supple_Figures20221215-1.pdf Supple_Table20221215-1.pdf
著者	Kajiwara, Yoshinori\| Tazawa, Hiroshi\| Yamada, Motohiko\| Kanaya, Nobuhiko\| Fushimi, Takuro\| Kikuchi, Satoru\| Kuroda, Shinji\| Ohara, Toshiaki\| Noma, Kazuhiro\| Yoshida, Ryuichi\| Umeda, Yuzo\| Urata, Yasuo\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
キーワード	Pancreatic cancer Chemoresistance MDSC GM-CSF Oncolytic virus
備考	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00262-022-03334-x\| This full-text of the article will be available in Nov. 2023.\|
発行日	2022-11-27
出版物タイトル	Cancer Immunology, Immunotherapy
巻	72巻
号	5号
出版者	Springer Science and Business Media LLC
開始ページ	1285
終了ページ	1300
ISSN	0340-7004
NCID	AA00598499
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022
論文のバージョン	author
PubMed ID	36436021
DOI	10.1007/s00262-022-03334-x
Web of Science KeyUT	000889040300003
関連URL	isVersionOf https://doi.org/10.1007/s00262-022-03334-x

Dual-targeted near-infrared photoimmunotherapy for esophageal cancer and cancer-associated fibroblasts in the tumor microenvironment

フルテキストURL	fulltext.pdf
著者	Sato, Hiroaki\| Noma, Kazuhiro\| Ohara, Toshiaki\| Kawasaki, Kento\| Akai, Masaaki\| Kobayashi, Teruki\| Nishiwaki, Noriyuki\| Narusaka, Toru\| Komoto, Satoshi\| Kashima, Hajime\| Katsura, Yuki\| Kato, Takuya\| Kikuchi, Satoru\| Tazawa, Hiroshi\| Kagawa, Shunsuke\| Shirakawa, Yasuhiro\| Kobayashi, Hisataka\| Fujiwara, Toshiyoshi\|
発行日	2022-11-23
出版物タイトル	Scientific Reports
巻	12巻
号	1号
出版者	Nature Portfolio
開始ページ	20152
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
PubMed ID	36418422
DOI	10.1038/s41598-022-24313-3
Web of Science KeyUT	000887936300054
関連URL	isVersionOf https://doi.org/10.1038/s41598-022-24313-3

Gastric linitis plastica with autoimmune pancreatitis diagnosed by an endoscopic ultrasonography-guided fine-needle biopsy: A case report

フルテキストURL	fulltext20221130-3.pdf
著者	Sato, Ryosuke\| Matsumoto, Kazuyuki\| Kanzaki, Hiromitsu\| Matsumi, Akihiro\| Miyamoto, Kazuya\| Morimoto, Kosaku\| Terasawa, Hiroyuki\| Fujii, Yuki\| Yamazaki, Tatsuhiro\| Uchida, Daisuke\| Tsutsumi, Koichiro\| Horiguchi, Shigeru\| Kato, Hironari\|
キーワード	Endoscopic ultrasound-guided fine needle aspiration Linitis plastica Autoimmune pancreatitis Paraneoplastic syndromes Case report
備考	Sato R, Matsumoto K, Kanzaki H, Matsumi A, Miyamoto K, Morimoto K, Terasawa H, Fujii Y, Yamazaki T, Uchida D, Tsutsumi K, Horiguchi S, Kato H. Gastric linitis plastica with autoimmune pancreatitis diagnosed by an endoscopic ultrasonography-guided fine-needle biopsy: A case report. World J Clin Cases 2022; 10(31): 11607-11616 [PMID: 36387831 DOI: 10.12998/wjcc.v10.i31.11607]\|
発行日	2022-11-6
出版物タイトル	World Journal of Clinical Cases
巻	10巻
号	31号
出版者	Baishideng Publishing Group Inc.
開始ページ	11607
終了ページ	11616
ISSN	2307-8960
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	©The Author(s) 2022
論文のバージョン	publisher
PubMed ID	36387831
DOI	10.12998/wjcc.v10.i31.11607
Web of Science KeyUT	000885256200043

Neonatal hemochromatosis with epsilon gamma delta beta-thalassemia: a case report and analysis of serum iron regulators

フルテキストURL	fulltext.pdf
著者	Tsuge, Mitsuru\| Kodera, Aya\| Sumitomo, Hiromi\| Araki, Tooru\| Yoshida, Ryuichi\| Yasui, Kazuya\| Sato, Hiroki\| Washio, Yosuke\| Washio, Kana\| Shigehara, Kenji\| Yashiro, Masato\| Yagi, Takahito\| Tsukahara, Hirokazu\|
キーワード	Neonatal hemochromatosis Thalassemia Liver transplantation Gestational alloimmune liver disease Case report Hepcidin Ineffective erythropoiesis Growth differentiation factor-15
発行日	2022-10-29
出版物タイトル	BMC Pediatrics
巻	22巻
号	1号
出版者	BMC
開始ページ	622
ISSN	1471-2431
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022.
論文のバージョン	publisher
PubMed ID	36309641
DOI	10.1186/s12887-022-03706-3
Web of Science KeyUT	000876287400002
関連URL	isVersionOf https://doi.org/10.1186/s12887-022-03706-3

History of Transcatheter Arterial Chemoembolization Predicts the Efficacy of Hepatic Arterial Infusion Chemotherapy in Hepatocellular Carcinoma Patients

JaLCDOI	10.18926/AMO/64120
フルテキストURL	76_6_695.pdf
著者	Onishi, Hideki\| Nouso, Kazuhiro\| Takaki, Akinobu\| Oyama, Atsushi\| Adachi, Takuya\| Wada, Nozomu\| Takeuchi, Yasuto\| Shiraha, Hidenori\| Okada, Hiroyuki\|
抄録	This study sought to identify factors that are predictive of a therapeutic response to hepatic arterial infusion chemotherapy (HAIC) by focusing on the number of prior transcatheter arterial chemoembolization (TACE) sessions. To determine the parameters predicting a good response to HAIC, we retrospectively analyzed 170 patients with hepatocellular carcinoma (HCC) who received HAIC regimens comprising low-dose cisplatin combined with 5-fluorouracil (LFP) or cisplatin (CDDP) for the first time. In both the LFP and CDDP regimens, the response rates were significantly lower in patients with three or more prior TACE sessions than in those with two or fewer prior TACE sessions (LFP 57% versus 28%; p=0.01, CDDP 27% versus 6%; p=0.01). Multivariable logistic regression analysis revealed that the number of prior TACE sessions (≥ 3) was significantly associated with non-responder status (odds ratio 4.17, 95% Confidence Interval (CI) 1.76-9.86) in addition to the HAIC regimen. Multivariable analysis using the Cox proportional hazards model revealed that a larger number of prior TACE sessions (≥ 3) was a significant risk factor for survival (hazard ratio 1.60, 95% CI 1.12-2.29) in addition to Child-Pugh class, serum alpha-fetoprotein concentration, and maximum diameter of HCC. HCC patients who receive fewer prior TACE sessions (≤ 2) were found to be better responders to HAIC.
キーワード	hepatic arterial infusion chemotherapy hepatocellular carcinoma refractory transcatheter arterial chemoembolization
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-12
巻	76巻
号	6号
出版者	Okayama University Medical School
開始ページ	695
終了ページ	703
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	36549772
Web of Science KeyUT	000905195100010

Surgical Resection for Local and Lateral Lymph Node Recurrence of MSI-high Cecal Cancer with the BRAF V600E Mutation

JaLCDOI	10.18926/AMO/64043
フルテキストURL	76_5_605.pdf
著者	Teraishi, Fuminori\| Jikuhara, Atsushi\| Ogawa, Ryunosuke\| Fujiwara, Toshiyoshi\|
抄録	An 84-year-old female underwent open right hemicolectomy with D3 lymph node dissection for cecal cancer, pathologically identified as pT4aN2M0 Stage IIIc and BRAF mutation-positive. Due to early recurrence of abdominal wall and right lateral lymph nodes, the patient was treated with FOLFOXIRI+Bevacizumab. Imaging after 5 courses of chemotherapy found tumor shrinkage and no new metastases. The patient did not tolerate chemotherapy well, and tumor resection was performed. Microsatellite instability (MSI) testing using multiplex polymerase chain reaction (PCR) fragment analysis revealed MSI-high status. The patient is currently recurrence-free without chemotherapy at 1 year postoperatively. BRAF-mutated colorectal cancer has a poor prognosis, and may require resection of the metastatic or recurrent tumor after comprehensive evaluation.
キーワード	BRAF V600E mutation cecal cancer, MSI-high
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2022-10
巻	76巻
号	5号
出版者	Okayama University Medical School
開始ページ	605
終了ページ	608
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	36352809
Web of Science KeyUT	000884907100015

Oncolytic virus-mediated p53 overexpression promotes immunogenic cell death and efficacy of PD-1 blockade in pancreatic cancer

フルテキストURL	fulltext.pdf
著者	Araki, Hiroyuki\| Tazawa, Hiroshi\| Kanaya, Nobuhiko\| Kajiwara, Yoshinori\| Yamada, Motohiko\| Hashimoto, Masashi\| Kikuchi, Satoru\| Kuroda, Shinji\| Yoshida, Ryuichi\| Umeda, Yuzo\| Urata, Yasuo\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
発行日	2022-12-15
出版物タイトル	Molecular Therapy - Oncolytics
巻	27巻
出版者	Cell Press
開始ページ	3
終了ページ	13
ISSN	2372-7705
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Author(s).
論文のバージョン	publisher
PubMed ID	36212775
DOI	10.1016/j.omto.2022.09.003
Web of Science KeyUT	000870232500001
関連URL	isVersionOf https://doi.org/10.1016/j.omto.2022.09.003

Clinical impact of lipid injectable emulsion in internal medicine inpatients exclusively receiving parenteral nutrition: a propensity score matching analysis from a Japanese medical claims database

フルテキストURL	fulltext.pdf
著者	Takagi, Kosei\| Murotani, Kenta\| Kamoshita, Satoru\| Kuroda, Akiyoshi\|
キーワード	Parenteral nutrition Lipid injectable emulsion Medical inpatient Clinical outcome Real-world data
発行日	2022-10-27
出版物タイトル	BMC Medicine
巻	20巻
号	1号
出版者	BMC
開始ページ	371
ISSN	1741-7015
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022.
論文のバージョン	publisher
PubMed ID	36289527
DOI	10.1186/s12916-022-02568-x
Web of Science KeyUT	000873785800002
関連URL	isVersionOf https://doi.org/10.1186/s12916-022-02568-x