検索結果 - 岡山大学学術成果リポジトリ

Backside Irradiation of Ultraviolet-A for Correcting Nonuniformity Error of Gafchromic XR-QA2 Films

フルテキストURL	fulltext.pdf
著者	Tanki, Nobuyoshi\| Goto, Sachiko\| Katsuda, Toshizo\| Gotanda, Rumi\| Gotanda, Tatsuhiro\| Kuwano, Tadao\|
キーワード	Backside irradiation computed tomography reflective type radiochromic film ultraviolet radiation
発行日	2024-10
出版物タイトル	Journal of Medical Physics
巻	49巻
号	4号
出版者	Medknow Publications
開始ページ	563
終了ページ	567
ISSN	0971-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 Journal of Medical Physics
論文のバージョン	publisher
PubMed ID	39926142
DOI	10.4103/jmp.jmp_87_24
Web of Science KeyUT	001422004700010
関連URL	isVersionOf https://doi.org/10.4103/jmp.jmp_87_24

Spatiotemporal expression pattern of dyslexia susceptibility 1 candidate 1 (DYX1C1) during rat cerebral cortex development

フルテキストURL	fulltext.pdf
著者	Zensho, Kazumasa\| Miyazaki, Ikuko\| Isse, Aika\| Misawa, Ichika\| Masai, Kaori\| Oka, Makio\| Tsukahara, Hirokazu\| Asanuma, Masato\|
発行日	2025-02-12
出版物タイトル	Pediatric Research
出版者	Springer Science and Business Media LLC
ISSN	0031-3998
NCID	AA00770262
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	39939521
DOI	10.1038/s41390-025-03920-6
Web of Science KeyUT	001418931400001
関連URL	isVersionOf https://doi.org/10.1038/s41390-025-03920-6

A capsidless (+)RNA yadokarivirus hosted by a dsRNA virus is infectious as particles, cDNA, and dsRNA

フルテキストURL	fulltext.pdf
著者	Fadli, Muhammad\| Hisano, Sakae\| Novoa, Guy\| Castón, José R.\| Kondo, Hideki\| Suzuki, Nobuhiro\|
キーワード	yadokarivirus hetero-encapsidation partner dsRNA virus fungal virus Aspergillus foetidus neo-lifestyle
発行日	2025-02-13
出版物タイトル	Journal of Virology
巻	99巻
号	3号
出版者	American Society for Microbiology
開始ページ	e02166-24
ISSN	0022-538X
NCID	AA00708779
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 Fadli et al.
論文のバージョン	publisher
PubMed ID	39945536
DOI	10.1128/jvi.02166-24
Web of Science KeyUT	001421220200001
関連URL	isVersionOf https://doi.org/10.1128/jvi.02166-24

LRP4 and Agrin Are Modulated by Cartilage Degeneration and Involved in β-Catenin Signaling in Human Articular Chondrocytes

フルテキストURL	fulltext.pdf
著者	Naniwa, Shuichi\| Nishida, Keiichiro\| Yoshida, Aki\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Ohtsuki, Takashi\| Hotta, Yoshifumi\| Shimizu, Noriyuki\| Ichikawa, Chinatsu\| Lin, Deting\| Otsuka, Noriaki\| Ozaki, Toshifumi\|
キーワード	osteoarthritis chondrocyte mechanical stress LRP4 Agrin β-catenin SOX9
発行日	2025-01-24
出版物タイトル	International Journal of Molecular Sciences
巻	26巻
号	3号
出版者	MDPI
開始ページ	1007
ISSN	1661-6596
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 by the authors.
論文のバージョン	publisher
PubMed ID	39940775
DOI	10.3390/ijms26031007
Web of Science KeyUT	001418599900001
関連URL	isVersionOf https://doi.org/10.3390/ijms26031007

Characteristics of porcine oocyte-cumulus complexes derived from various sizes of antral follicles and classified by brilliant cresyl blue staining, and developmental competence of the oocytes

著者	Van, Phong Ngoc\| Do, Son Quang\| Fonseka, Wanniarachchige Tharindu Lakshitha\| Wakai, Takuya\| Funahashi, Hiroaki\|
備考	© 2025 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/\| This fulltext file will be available in Feb. 2026.\|
発行日	2025-04-01
出版物タイトル	Theriogenology
巻	236巻
出版者	Elsevier BV
開始ページ	74
終了ページ	81
ISSN	0093-691X
NCID	AA00862972
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 Elsevier Inc.
論文のバージョン	author
PubMed ID	39922120
DOI	10.1016/j.theriogenology.2025.02.001
関連URL	isVersionOf https://doi.org/10.1016/j.theriogenology.2025.02.001

Mitochondrial content and mtDNA copy number in spermatozoa and penetrability into oocytes

著者	Nguyen, Hai Thanh\| Do, Son Quang\| Wakai, Takuya\| Funahashi, Hiroaki\|
キーワード	Spermatozoa Mitochondria Mitochondrial DNA Penetrability Spermatogenesis
備考	© 2024 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/\| This fulltext file will be available in Dec. 2025.\|
発行日	2025-03-01
出版物タイトル	Theriogenology
巻	234巻
出版者	Elsevier BV
開始ページ	125
終了ページ	132
ISSN	0093-691X
NCID	AA00862972
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 Elsevier Inc.
論文のバージョン	author
PubMed ID	39689446
DOI	10.1016/j.theriogenology.2024.12.012
Web of Science KeyUT	001413808000001
関連URL	isVersionOf https://doi.org/10.1016/j.theriogenology.2024.12.012

The effects of soybeans and its derivatives on oral diseases: a narrative review

フルテキストURL	fulltext.pdf
著者	Canyan, Kuang\| Arias, Zulema Rosalia\| Omori, Kazuhiro\| Yamamoto, Tadashi\| Shinoda-Ito, Yuki\| Takashiba, Shogo\|
キーワード	soybean soy products oral diseases dental application antibacterial effect antioxidant anticancer
発行日	2025-01
出版物タイトル	International Journal of Food Science and Technology
巻	60巻
号	1号
出版者	Oxford University Press (OUP)
開始ページ	vvae044
ISSN	0950-5423
NCID	AA10710609
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025.
論文のバージョン	publisher
DOI	10.1093/ijfood/vvae044
Web of Science KeyUT	001414446300002
関連URL	isVersionOf https://doi.org/10.1093/ijfood/vvae044

Effects of caffeine on the longevity and locomotion activity of the common green bottle fly, Lucilia sericata (Diptera: Calliphoridae)

フルテキストURL	fulltext.pdf
著者	Naing, Shine Shane\| Fujioka, Haruna\| Matsuura, Teruhisa\| Miyatake, Takahisa\|
キーワード	Caffeine Life span Locomotor activity Pollinator
備考	The version of record of this article, first published in Applied Entomology and Zoology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s13355-025-00893-0\|
発行日	2025-02-09
出版物タイトル	Applied Entomology and Zoology
出版者	Springer Science and Business Media LLC
ISSN	0003-6862
NCID	AA00543238
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
DOI	10.1007/s13355-025-00893-0
Web of Science KeyUT	001416045200001
関連URL	isVersionOf https://doi.org/10.1007/s13355-025-00893-0

The antimalarial activity of transdermal N-89 mediated by inhibiting ERC gene expression in P. Berghei-infected mice

フルテキストURL	fulltext.pdf
著者	Matsumori, Hiroaki\| Dinh, Thi Quyen\| Miyoshi, Shin-ichi\| Morita, Masayuki\| Kim, Hye-Sook\|
キーワード	Synthetic antimalarial endoperoxide Transdermal N-89 Artemisinin In vivo Abnormal trophozoite Endoplasmic reticulum-resident calcium-binding protein (ERC) Parasite egress-related gene
発行日	2025-06
出版物タイトル	Parasitology International
巻	106巻
出版者	Elsevier BV
開始ページ	103026
ISSN	1383-5769
NCID	AA11112001
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Authors.
論文のバージョン	publisher
PubMed ID	39740755
DOI	10.1016/j.parint.2024.103026
Web of Science KeyUT	001414482100001
関連URL	isVersionOf https://doi.org/10.1016/j.parint.2024.103026

Nano/microparticle-based tough and recyclable polymers toward a sustainable society

フルテキストURL	fulltext.pdf
著者	Sasaki, Yuma\| Nishizawa, Yuichiro\| Kureha, Takuma\| Suzuki, Daisuke\|
発行日	2025
出版物タイトル	Chemical Communications
巻	61巻
号	24号
出版者	Royal Society of Chemistry (RSC)
開始ページ	4606
終了ページ	4620
ISSN	1359-7345
NCID	AA11071130
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Royal Society of Chemistry 2025
論文のバージョン	publisher
PubMed ID	39927609
DOI	10.1039/d5cc00543d
Web of Science KeyUT	001416656500001
関連URL	isVersionOf https://doi.org/10.1039/d5cc00543d

Social Change and Social Participation in a Planned City : the Case of Canberra

フルテキストURL	fulltext20250207-01.pdf
著者	Nobe, Masao\|
発行日	1990
資料タイプ	学位論文
授与大学	The Australian National University
言語	英語

A case of pancreatic ductal adenocarcinoma growing within the pancreatic duct mimicking an intraductal tubulopapillary neoplasm

フルテキストURL	fulltext.pdf
著者	Sato, Ryosuke\| Matsumoto, Kazuyuki\| Uka, Mayu\| Takagi, Kosei\| Nishida, Kenji\| Tanaka, Takehiro\| Fujii, Yuki\| Tsutsumi, Koichiro\| Horiguchi, Shigeru\| Otsuka, Motoyuki\|
キーワード	Pancreatic intraductal neoplasms Pancreatic carcinoma Intraductal tubulopapillary neoplasm Genetic testing
備考	The version of record of this article, first published in Clinical Journal of Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12328-025-02098-y\|
発行日	2025-02-05
出版物タイトル	Clinical Journal of Gastroenterology
巻	18巻
号	2号
出版者	Springer Science and Business Media LLC
開始ページ	376
終了ページ	382
ISSN	1865-7257
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	39910028
DOI	10.1007/s12328-025-02098-y
Web of Science KeyUT	001415187700001
関連URL	isVersionOf https://doi.org/10.1007/s12328-025-02098-y

A Rare Case of Compression Neuritis due to Intraorbital Arteriovenous Fistula (IOAVF) Mimicking Retrobulbar Optic Neuritis

JaLCDOI	10.18926/AMO/68363
フルテキストURL	79_1_059.pdf
著者	Minakawa, Shun\| Hirano, Masayuki\| Takahashi, Kazuya\| Imamura, Yuta\| Watanabe, Takashi\|
抄録	Intraorbital arteriovenous fistulas (IOAVFs) are rare vascular abnormalities. We describe a case of an IOAVF featuring a direct shunt between the accessory meningeal artery and the superior ophthalmic artery. A 55-year-old woman presented with a 1-month history of visual impairment in her right eye, and magnetic resonance imaging (MRI) revealed optic neuritis-like findings. Steroid pulse therapy temporarily resolved visual impairment. However, 1 month later, she experienced decreased visual acuity, ocular conjunctival hyperemia, edema, and a pulsatile murmur. Contrast-enhanced MRI and digital subtraction angiography revealed compression optic neuropathy due to an IOAVF. Following successful treatment with transarterial embolization, her symptoms disappeared.
キーワード	intraorbital arteriovenous fistula compressive optic neuropathy accessory meningeal artery superior ophthalmic vein
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	59
終了ページ	64
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012161
Web of Science KeyUT	001440463800008

Photoinitiators Induce Histamine Production in Human Mast Cells

JaLCDOI	10.18926/AMO/68362
フルテキストURL	79_1_051.pdf
著者	Miura, Taro\| Kawasaki, Yoichi\| Hamano, Hirofumi\| Zamami, Yoshito\| Sendo, Toshiaki\|
抄録	Photoinitiators are used in the manufacture of many daily products, and may produce harmful effects due to their cytotoxicity. They have also been detected in human serum. Here, we investigated the histamine-producing effects in HMC-1 cells and the inflammatory cytokine release effects in RAW264 cells for four photoinitiators: 1-hydroxycyclohexyl phenyl ketone; 2-isopropylthioxanthone; methyl 2-benzoylbenzoate; and 2-methyl-4´-(methylthio)-2-morpholinopropiophenone. All four promoted histamine production in HMC-1 cells; however, they did not significantly affect the release of inflammatory cytokines in RAW264 cells. These findings suggest that these four photoinitiators induce inflammatory cytokine-independent histamine production, potentially contributing to histamine-mediated chronic inflammation in vitro.
キーワード	photoinitiator ink injection histamine inflammation
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	51
終了ページ	58
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012160
Web of Science KeyUT	001440463800007

Immediate Effects of a Single Home-based Rehabilitation Treatment on Balance Performance and Toe-Grip Strength in Elderly Subjects Continuing the Same Rehabilitation Program

JaLCDOI	10.18926/AMO/68361
フルテキストURL	79_1_047.pdf
著者	Kojima, Kazunori\| Ujikawa, Takuya\| Ono, Toshiro\|
抄録	We assessed the immediate effects of a home-based rehabilitation (HBR) program on the balance performance and toe-grip strength of 29 older adults (mean±SD age of 75.1±9.9; 16 males, 13 females) who were participating in HBR services provided by Japan’s nursing care insurance system. Their toe-grip strength and balance performance were measured before and after the HBR program. The subjects’ toe-grip strength was significantly improved after the treatment. The subjects who had had a stroke showed a significant improvement after HBR. Contrarily, no significant difference was observed in the subjects’ functional reach results or their one-leg standing time. These results indicate that the exercise regimen provided in the HBR program led to increased excitability of motor units and immediately enhanced the subjects’ toe-grip strength.
キーワード	home-based rehabilitation toe-grip strength balance performance
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	47
終了ページ	50
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012159
Web of Science KeyUT	001440463800006
レファレンス	Kira K: The basic approach to determining the effects of cerebrovascular disease and in the maintenance phase of rehabilitation. Phys Ther Jpn (2011) 38: 246-248 (in Japanese).\| Ito T: Role of physical therapists at the home health care. Phys Ther Jpn (2001) 28: 399-402 (in Japanese).\| Kojima K, Nakayama T, Watanabe A, Yoshimura S, Yamaya T, Sato K, Doi A, Ogino T, Moriyasu N and Watanabe S: Activities of daily living and quality of life assessment during home-based rehabilitation. Jpn J Compr Rehabil Sci (2017) 8: 30-36.\| Benvenuti F, Ferrucci L, Guralnik JM, Gangemi S and Baroni A: Foot pain and disability in older persons: an epidemiologic survey. J Am Geriatr Soc (1995) 43: 479-484.\| Kojima K, Kamai D, Yamamoto A, Tsuchitani Y and Kataoka H: The Effect of toe-grasping exercises on balance ability in home-based rehabilitation: a randomized controlled trial by block randomization. Phys Ther Res (2021) 24: 272-279.\| Elm E von, Altman DG, Egger M, Pocock SJ, Gøtzsche PC and Vandenbroucke JP: The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Int J Surg (2014) 12: 1495-1499.\| Uritani D, Fukumoto T and Matsumoto D: Intrarater and interrater reliabilities for a toe grip dynamometer. J Phys Ther Sci (2012) 24: 639-643.\| Vellas BJ, Wayne SJ, Romero L, Baumgartner RN, Rubenstein LZ and Garry PJ: One-Leg Balance Is an important predictor of injurious falls in older persons. J Am Geriatr Soc (1997) 45: 735-738.\| Duncan PW, Weiner DK, Chandler J and Studenski S: Functional Reach: A new clinical measure of balance. J Gerontol (1990) 45: M192-197.\| Sale DG: Postactivation Potentiation: Role in human performance. Exer Sport Sci Rev (2002) 30: 138-143.\| Gossen ER and Sale DG: Effect of postactivation potentiation on dynamic knee extension performance. Eur J Appl Physiol (2000) 83: 524-530.\| Jones DA, Newham DJ and Torgan C: Mechanical influences on long-lasting human muscle fatigue and delayed-onset pain. J Physiol (1989) 412: 415-427.\| Eston RG, Finney S, Baker S and Baltzopoulos V: Muscle tenderness and peak torque changes after downhill running following a prior bout of isokinetic eccentric exercise. J Sports Sci (1996) 14: 291-299.\| Onuma R, Soutome Y, Asada Y, Kurihara Y, Fujino Y and Matsuda T: Immediate effect of exercise therapy using ʼspiderʼ for chronic stroke patients with hemiplegia. Rigakuryoho Kagaku (2020) 35: 791-795 (in Japanese).\|

Could the Trabecular Bone Score Be a Complementary Tool for Evaluating Degenerative Lumbar Vertebrae?

JaLCDOI	10.18926/AMO/68360
フルテキストURL	79_1_039.pdf
著者	Takao, Shinichiro\| Uotani, Koji\| Misawa, Haruo\| Tetsunaga, Tomoko\| Shinohara, Kensuke\| Yamane, Kentaro\| Oda, Yoshiaki\| Tsuji, Hironori\| Kajiki, Yuya\| Ozaki, Toshifumi\|
抄録	Evaluating vertebral bone mass and quality in the elderly poses challenges due to degenerative changes. This study aims to elucidate the usefulness of the trabecular bone score (TBS) by examining the relationship between bone mineral density (BMD), TBS, and Hounsfield unit (HU) values. A retrospective analysis of 599 vertebrae from 152 patients (mean age 69.0 years; range 44-89; 74 males and 78 females) undergoing dual-energy X-ray absorptiometry (DXA) and CT scans was conducted. Vertebrae were categorized into three grades based on the degree of degeneration. The TBS was calculated from DXA images, and the HU value was measured by placing a region of interest on an axial image of the vertebral mid-body. One-way analysis of variance and Pearson’s correlation tests were employed to investigate the relationship between BMD and TBS or HU values. While lumbar BMD significantly increased (p<0.01) with degenerative changes, TBS and HU values showed no significant differences. The correlations between lumbar BMD and TBS values, and between BMD and HU values, were stronger without degenerative changes than with degenerative changes. Significantly different HU values were observed between the right and left sides of severely degenerated vertebrae. Severe degenerative changes, particularly those associated with sclerosis, may impact HU values. TBS exhibits greater potential than HU values as a complementary tool.
キーワード	trabecular bone score computed tomography Hounsfield unit lumbar degenerative change radiodensity
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	39
終了ページ	45
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012158
Web of Science KeyUT	001440463800005

Establishment of a rapid and quantitative method for detecting the range of infection exposure in preclinical dental education

フルテキストURL	fulltext.pdf
著者	Ueda, Ayaka\| Shinoda-Ito, Yuki\| Takeuchi-Hatanaka, Kazu\| Ito, Takashi\| Ono, Shintaro\| Hirai, Kimito\| Omori, Kazuhiro\| Yamamoto, Tadashi\| Takashiba, Shogo\|
キーワード	Dental education Infection control Fluorescent dye Adenosine triphosphate Lactobacillus
発行日	2025-02-08
出版物タイトル	BMC Oral Health
巻	25巻
号	1号
出版者	BMC
開始ページ	199
ISSN	1472-6831
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025.
論文のバージョン	publisher
PubMed ID	39923078
DOI	10.1186/s12903-025-05584-4
Web of Science KeyUT	001416641300005
関連URL	isVersionOf https://doi.org/10.1186/s12903-025-05584-4

Voice analysis and deep learning for detecting mental disorders in pregnant women: a cross-sectional study

フルテキストURL	fulltext.pdf
著者	Ooba, Hikaru\| Maki, Jota\| Masuyama, Hisashi\|
キーワード	Perinatal mental disorders Voice analysis Machine learning Screening Pregnant women
発行日	2025-02-08
出版物タイトル	Discover Mental Health
巻	5巻
号	1号
出版者	Springer Nature
開始ページ	12
ISSN	2731-4383
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	39920468
DOI	10.1007/s44192-025-00138-0
Web of Science KeyUT	001415532800001
関連URL	isVersionOf https://doi.org/10.1007/s44192-025-00138-0

Cancer-associated fibroblasts promote pro-tumor functions of neutrophils in pancreatic cancer via IL-8: potential suppression by pirfenidone

フルテキストURL	fulltext.pdf
著者	Yagi, Tomohiko\| Kagawa, Shunsuke\| Nogi, Shohei\| Taniguchi, Atsuki\| Yoshimoto, Masashi\| Suemori, Kanto\| Nagai, Yasuo\| Fujita, Shuto\| Kuroda, Shinji\| Kikuchi, Satoru\| Kakiuchi, Yoshihiko\| Teraishi, Fuminori\| Takagi, Kosei\| Ohara, Toshiaki\| Tazawa, Hiroshi\| Fujiwara, Toshiyoshi\|
キーワード	Cancer-associated fibroblasts Neutrophil Anti-fibrotic agent Pirfenidone
発行日	2025-02-04
出版物タイトル	Cancer Immunology, Immunotherapy
巻	74巻
号	3号
出版者	Springer
開始ページ	96
ISSN	0340-7004
NCID	AA00598499
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	39904796
DOI	10.1007/s00262-025-03946-z
Web of Science KeyUT	001413348800005
関連URL	isVersionOf https://doi.org/10.1007/s00262-025-03946-z

Retrospective Analysis of the Safety of High-Volume Dental Articaine Preparations for Japanese Patients

JaLCDOI	10.18926/AMO/68356
フルテキストURL	79_1_031.pdf
著者	Maeda, Shigeru\| Pimkhaokham, Atiphan\| Yoshida, Michihiro\| Hosoi, Hiroki\| Ohshima, Ayako\| Kurisu, Ryoko\| Utsumi, Nozomi\| Higuchi, Hitoshi\| Miyawaki, Takuya\|
抄録	We retrospectively analyzed the safety of the use of articaine, an amide-type local anesthetic, in Japanese dental patients (n=300) treated in Thailand in 2015-2017. The dosage, adverse events (AEs) caused by local anesthesia, and treatment efficacy were examined. Articaine, which is safe for patients with liver impairments due to its unique metabolism, has not been thoroughly tested in Japan for doses above 5.1 mL. Eighty of the present patients had undergone root canal treatment (RCT), 71 underwent tooth extraction, and 149 underwent implant-related surgery. More than three articaine cartridges were used in 41 patients, and no AEs occurred in these cases. The only AE occurred in a 52-year-old woman who was treated with three cartridges and presented with what appeared to be hyperventilation syndrome; she later recovered and received her dental treatment as scheduled. Most treatments were completed with three or fewer cartridges, suggesting that this number is generally sufficient. Our findings, particularly the low AE risk even with doses exceeding three cartridges, support the potential applicability of the overseas recommended maximum dose of articaine (7 mg/kg) in Japanese patients. This conclusion is significant for advancing dental anesthetic practices and ensuring patient safety and treatment efficacy in Japan.
キーワード	dental anesthesia local anesthesia drug-related side effect adverse reaction
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	31
終了ページ	37
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012157
Web of Science KeyUT	001440463800004