検索結果 - 岡山大学学術成果リポジトリ

Dexmedetomidine improves acute lung injury by activating autophagy in a rat hemorrhagic shock and resuscitation model

フルテキストURL	fulltext.pdf
著者	Lu, Yifu\| Shimizu, Hiroko\| Nakamura, Ryu\| Li, Yaqiang\| Sakamoto, Risa\| Omori, Emiko\| Takahashi, Toru\| Morimatsu, Hiroshi\|
発行日	2023-03-16
出版物タイトル	Scientific Reports
巻	13巻
号	1号
出版者	Nature Research
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	36927753
DOI	10.1038/s41598-023-31483-1
Web of Science KeyUT	000984357200057
関連URL	isVersionOf https://doi.org/10.1038/s41598-023-31483-1

Association between depression in chronic phase and future clinical outcome of patients with schizophrenia

フルテキストURL	K0006810_abstract_review.pdf K0006810_fulltext.pdf K0006810_other_Tables.pdf K0006810_summary.pdf
著者	山田裕士\|
発行日	2023-03-24
資料タイプ	学位論文
学位授与番号	甲第6810号
学位授与年月日	2023-03-24
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022

The validity of atypical psychosis diagnostic criteria to detect anti-NMDA receptor encephalitis with psychiatric symptoms

フルテキストURL	K0006792_abstract_review.pdf K0006792_fulltext.pdf K0006792_summary.pdf
著者	樋之津健二\|
発行日	2023-03-24
資料タイプ	学位論文
学位授与番号	甲第6792号
学位授与年月日	2023-03-24
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	© 2022 Elsevier B.V.

Association between prehospital advanced life support by emergency medical services personnel and neurological outcomes among adult out-of-hospital cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation: A secondary analysis of the SAVE-J II study

フルテキストURL	fulltext.pdf
著者	Yumoto, Tetsuya\| Hongo, Takashi\| Hifumi, Toru\| Inoue, Akihiko\| Sakamoto, Tetsuya\| Kuroda, Yasuhiro\| Yorifuji, Takashi\| Nakao, Atsunori\| Naito, Hiromichi\| SAVE-J II study group\|
発行日	2023-04-11
出版物タイトル	Journal of the American College of Emergency Physicians Open
巻	4巻
号	2号
出版者	Wiley
開始ページ	e12948
ISSN	2688-1152
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 The Authors.
論文のバージョン	publisher
PubMed ID	37064164
DOI	10.1002/emp2.12948
Web of Science KeyUT	000969175200001
関連URL	isVersionOf https://doi.org/10.1002/emp2.12948

Fucosyltransferase 8 (FUT8) and core fucose expression in oxidative stress response

フルテキストURL	fulltext.pdf
著者	Kyunai, Yuki\| Sakamoto, Mika\| Koreishi, Mayuko\| Tsujino, Yoshio\| Satoh, Ayano\|
発行日	2023-02-13
出版物タイトル	PLoS ONE
巻	18巻
号	2号
出版者	Public Library of Science
開始ページ	e0281516
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 Kyunai et al.
論文のバージョン	publisher
PubMed ID	36780470
DOI	10.1371/journal.pone.0281516
Web of Science KeyUT	000966632200001
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0281516

Relationships between squamous cell carcinoma antigen and cytokeratin 19 fragment values and renal function in oral cancer patients

フルテキストURL	fulltext20230428-01.pdf
著者	Obata, K.\| Yutori, H.\| Yoshida, K.\| Sakamoto, Y.\| Ono, K.\| Ibaragi, S.\|
キーワード	Oral cancer Tumor markers Squamous cell carcinoma Tumor antigens CYFRA cytokeratin fragment Renal function
備考	© 2022 International Association of Oral and Maxillofacial Surgeons. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.ijom.2022.08.019. \| This fulltext file will be available in Apr. 2024.\|
発行日	2023-04
出版物タイトル	International Journal of Oral and Maxillofacial Surgery
巻	52巻
号	4号
出版者	Elsevier BV
開始ページ	417
終了ページ	422
ISSN	0901-5027
NCID	AA10682150
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 International Association of Oral and Maxillofacial Surgeons.
論文のバージョン	author
PubMed ID	36096859
DOI	10.1016/j.ijom.2022.08.019
Web of Science KeyUT	000953117300001
関連URL	isVersionOf https://doi.org/10.1016/j.ijom.2022.08.019

Locally Advanced Rectal Cancer Invading the Gluteus Maximus Muscle Completely Responded to Total Neoadjuvant Therapy

JaLCDOI	10.18926/AMO/65152
フルテキストURL	77_2_209.pdf
著者	Sakamoto, Masaki\| Teraishi, Fuminori\| Shigeyasu Kunitoshi\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
抄録	A 70-year-old male with anal pain and fever was diagnosed with rectal cancer perforation and abscess in the right gluteus maximus (GM) muscle. He underwent a transverse colon colostomy followed by preoperative capecitabine+oxaliplatin. Some local control was achieved but a residual abscess was observed in the right GM muscle. To secure circumferential resection margin by tumor reduction, he received chemoradiotherapy as total neoadjuvant therapy (TNT) and underwent laparoscopic abdominoperineal resection, D3 lymph node dissection, combined coccyx resection, and partial resection of the right GM muscle. The skin defect and pelvic dead space were filled with a right lateral vastus lateral great muscle flap. Histopathologically, the resected specimen showed no tumor cells in the primary tumor or lymph nodes, indicating a pathological complete response (pCR). This case suggests that TNT might improve the R0 resection and pCR rates and overall survival.
キーワード	locally advanced rectal cancer total neoadjuvant therapy lateral vastus lateral great muscle flap
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2023-04
巻	77巻
号	2号
出版者	Okayama University Medical School
開始ページ	209
終了ページ	213
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37094960
Web of Science KeyUT	000982563800003

Personalized Preclinical Training in Dental Ergonomics and Endodontics in Undergraduate Dentistry Students (Pilot Study)

JaLCDOI	10.18926/AMO/65144
フルテキストURL	77_2_147.pdf
著者	Arias, Zulema\| Haines, Stephanie\| Yamamoto, Tadashi\| Hatanaka, Kazu\| Yamashiro, Keisuke\| Sonoi, Norihiro\| Takashiba, Shogo\|
抄録	The curriculum at the Department of Pathophysiology in the Periodontal Sciences program at Okayama University includes normative preclinical training (NPT) using phantoms. NPT is given to the whole class of 5 th year students divided in groups of 8 students/instructor. In 2019, an innovative personalized preclinical training (PPT) pilot study was implemented for this group of students whereby two students, each with their own dental unit, were coached by one instructor. The main topics covered were dental ergonomics and endodontics. We aimed to evaluate the effectiveness of PPT in dental ergonomics and endodontics toward increasing the knowledge and future clinical skills of students who had already undergone NPT. A test on endodontics was taken before and after PPT. A questionnaire was completed to assess their perception of improvement regarding the above-mentioned topics. Test scores and questionnaire results both showed that the students’ level of knowledge and awareness of future clinical skills was significantly higher after PPT. This pilot study demonstrated that PPT increased the students’ knowledge and future clinical skills. As preclinical training forms the foundation for clinical practice, investment in future research regarding this personalized approach is likely to enhance students’ understanding and clinical performance.
キーワード	preclinical personalized education dental ergonomics endodontics clinical skills improvement undergraduate students
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-04
巻	77巻
号	2号
出版者	Okayama University Medical School
開始ページ	147
終了ページ	159
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37094952
Web of Science KeyUT	000982503800004

Protocol for a randomised, placebo-controlled, double-blinded clinical trial on the effect of oestrogen replacement on physical performance to muscle resistance exercise for older women with osteoarthritis of knee joint: the EPOK trial

フルテキストURL	fulltext.pdf
著者	Mitoma, Tomohiro\| Maki, Jota\| Ooba, Hikaru\| Eto, Eriko\| Takahashi, Kasumi\| Kondo, Tsunemasa\| Ikeda, Tomohiro\| Sakamoto, Yoko\| Mitsuhashi, Toshiharu\| Masuyama, Hisashi\|
キーワード	Oestrogen replacement therapy Knee osteoarthritis Muscle resistance exercise Sarcopenia Physical performance
発行日	2023-02-18
出版物タイトル	BMC Geriatrics
巻	23巻
号	1号
出版者	BMC
開始ページ	104
ISSN	1471-2318
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023.
論文のバージョン	publisher
PubMed ID	36800940
DOI	10.1186/s12877-023-03828-y
Web of Science KeyUT	000936860000001
関連URL	isVersionOf https://doi.org/10.1186/s12877-023-03828-y

Detection of Membrane Potential-Dependent Rhodopsin Fluorescence Using Low-Intensity Light Emitting Diode for Long-Term Imaging

フルテキストURL	fulltext.pdf
著者	Kawanishi, Shiho\| Kojima, Keiichi\| Shibukawa, Atsushi\| Sakamoto, Masayuki\| Sudo, Yuki\|
発行日	2023-01-25
出版物タイトル	ACS Omega
巻	8巻
出版者	American Chemical Society
開始ページ	4826
終了ページ	4834
ISSN	2470-1343
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 The Authors.
論文のバージョン	publisher
PubMed ID	36777568
DOI	10.1021/acsomega.2c06980
Web of Science KeyUT	000926216100001
関連URL	isVersionOf https://doi.org/10.1021/acsomega.2c06980

Behavioural osmoregulation during land invasion in fish: Prandial drinking and wetting of the dry skin

フルテキストURL	fulltext.pdf
著者	Katayama, Yukitoshi\| Tsukada, Takehiro\| Hyodo, Susumu\| Sakamoto, Hirotaka\| Sakamoto, Tatsuya\|
発行日	2022-12-07
出版物タイトル	Plos One
巻	17巻
号	12号
出版者	Public Library Science
開始ページ	e0277968
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Katayama et al.
論文のバージョン	publisher
PubMed ID	36477197
DOI	10.1371/journal.pone.0277968
Web of Science KeyUT	000925063300030
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0277968

Development, Disappearance, and Clinical Course of Melanosis Coli: Sex Differences in the Progression of Severity

JaLCDOI	10.18926/AMO/64362
フルテキストURL	77_1_57.pdf
著者	Katsumata, Ryo\| Manabe, Noriaki\| Monobe, Yasumasa\| Ayaki, Maki\| Suehiro, Mitsuhiko\| Fujita, Minoru\| Kamada, Tomoari\| Kawamoto, Hirofumi\| Haruma, Ken\|
抄録	Melanosis coli (MC) is an acquired colorectal disorder visualized as colonic mucosa pigmentation. Disease severity is confirmed based on MC depth, shape, and coloration, although the clinical course is not fully understood. This study sought to clarify characteristics of MC development and disappearance and to investigate its clinical course and severity. Contributors to MC grade progression were explored. This study reviewed MC cases discovered via colonoscopy at a single institution over a 10-year period. Of all 216 MC cases, 17 developing and 10 disappearing cases were detected. Anthranoid laxative use was a key factor: 29.4% of the developing cases had used such agents before the initial MC diagnosis, whereas 40% of disappearing cases had discontinued anthranoids prior to detection of MC disappearance. Among 70 grade I cases, progression to grade II occurred in 16 cases during a mean follow-up of 3.67±2.1 years (rate of progression=22.8%). Males more commonly showed progressive than stable grade I cases, and the probability of progression was higher for male than for female cases. An association between anthranoid administration and MC presence was presumed, and grade I MC was found to progress in severity over 5 years.
キーワード	melanosis sex characteristics laxatives colorectal neoplasms colonoscopy
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-02
巻	77巻
号	1号
出版者	Okayama University Medical School
開始ページ	57
終了ページ	64
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	36849146
Web of Science KeyUT	000952992100003

Differences in Stress Perception of Medical Students Depending on In-Person Communication and Online Communication during the COVID-19 Pandemic: A Japanese Cross-Sectional Survey

フルテキストURL	fulltext.pdf
著者	Tokumasu, Kazuki\| Nishimura, Yoshito\| Sakamoto, Yoko\| Obika, Mikako\| Kataoka, Hitomi\| Otsuka, Fumio\|
キーワード	COVID-19 medical student medical education in-person communication online communication stress perception
発行日	2023-01-15
出版物タイトル	International Journal of Environmental Research and Public Health
巻	20巻
号	2号
出版者	MDPI
開始ページ	1579
ISSN	1660-4601
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 by the authors.
論文のバージョン	publisher
PubMed ID	36674333
DOI	10.3390/ijerph20021579
Web of Science KeyUT	000915112800001
関連URL	isVersionOf https://doi.org/10.3390/ijerph20021579

Identification of quantitative trait loci associated with sorghum susceptibility to Asian stem borer damage

フルテキストURL	fulltext.pdf
著者	Osinde, Cyprian\| Sakamoto, Wataru\| Kajiya-Kanegae, Hiromi\| Sobhy, Islam S.\| Tugume, Arthur K.\| Nsubuga, Anthony M.\| Galis, Ivan\|
キーワード	Quantitative trait locus (QTL) stem borer herbivory BTx623 and NOG recombinant inbred lines (RILs) sorghum
発行日	2023-12-31
出版物タイトル	Journal Of Plant Interactions
巻	18巻
号	1号
出版者	Taylor & Francis Ltd
開始ページ	2153182
ISSN	1742-9145
NCID	AA11980303
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Author(s).
論文のバージョン	publisher
DOI	10.1080/17429145.2022.2153182
Web of Science KeyUT	000905581600001
関連URL	isVersionOf https://doi.org/10.1080/17429145.2022.2153182

岡山大学構内遺跡における水田稲作の開始年代 ―Ⅰ期中段階の堰の酸素同位体比年輪年代と炭素14年代―

タイトル（別表記）	The beginning date of wet rice cultivation at the of Okayama University site: Tree ring oxygen isotope dating and radiocarbon 14 age of weirs from the mid-I stage of the Yayoi period
JaLCDOI	10.18926/64199
フルテキストURL	jdc_002_018.pdf
著者	藤尾慎一郎\| 坂本稔\| 佐野雅規\|
抄録	This article clarifies the date when paddy field rice cultivation began at the archaeological site located within the Okayama University campus. The analysis used tree ring oxygen isotope dating and radiocarbon dating. When the oxygen isotope ratios of wood used in paddy weirs detected in the 23rd excavation season were examined, peaks could be seen in two places: in the 10th century BC and the 6th century BC. Since the weir was accompanied by mid-I stage Yayoi pottery, which was dated to the 6th century BC using radiocarbon dating, tree ring dating determined that the weir was made from wood cut down soon after 540 BC. Therefore, it was reaffirmed that one of the points of the mid-I stage can be dated to the middle of the 6th century BC. Next is the age of the early-I stage, when paddy field rice cultivation began on the Okayama Plain. In the Tsuruba area of the Nishikawazu archaeological site in Shimane Prefecture, where paddy field rice cultivation is thought to have begun at the same time as on the Okayama Plain, tree ring oxygen isotope dating of wood accompanied by early-I stage pottery has been reported. The date of 649 BC date means that one of the earliest stages of the early-I period dates to the middle of the 7th century BC. Therefore, we reaffirmed the view that paddy rice cultivation in the Chugoku region, such as Okayama and Shimane, began in the 7th century BC. It also became clear that the beginning of paddy field rice cultivation in the Chugoku region occurred at a time when the climate that had been the base of cold in the 10th century BC gradually warmed and the relatively humid climate began to turn to arid.
キーワード	土器付着炭化物：carbides adhering to pottery 酸素同位体比年輪年代法：tree ring oxygen isotope dating 炭素14年代法：radiocarbon dating 岡山大学構内遺跡：the Okayama University site 弥生前期：the early Yayoi period 水田稲作：wet rice cultivation 堰：weirs
Amo Type	研究ノート (Research note)
出版物タイトル	文明動態学
発行日	2023-03-25
巻	2巻
出版者	岡山大学文明動態学研究所
開始ページ	18
終了ページ	31
ISSN	2436-8326
資料タイプ	学術雑誌論文
言語	日本語
著作権者	© 2023 by RIDC
論文のバージョン	publisher

Mating experiences with the same partner enhanced mating activities of naive male medaka fish

フルテキストURL	fulltext.pdf
著者	Daimon, Masahiro\| Katsumura, Takafumi\| Sakamoto, Hirotaka\| Ansai, Satoshi\| Takeuchi, Hideaki\|
発行日	2022-11-16
出版物タイトル	Scientific Reports
巻	12巻
号	1号
出版者	Nature Portfolio
開始ページ	19665
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
PubMed ID	36385126
DOI	10.1038/s41598-022-23871-w
Web of Science KeyUT	000884825100096
関連URL	isVersionOf https://doi.org/10.1038/s41598-022-23871-w

Footedness for scratching itchy eyes in rodents

フルテキストURL	fulltext20221117-1.pdf
著者	Katayama, Yukitoshi\| Miura, Ayane\| Sakamoto, Tatsuya\| Takanami, Keiko\| Sakamoto, Hirotaka\|
キーワード	itchy eyes histamine gastrin-releasing peptide receptor footedness
発行日	2022-10-19
出版物タイトル	Proceedings of the Royal Society B: Biological Sciences
巻	289巻
号	1985号
出版者	The Royal Society
開始ページ	20221126
ISSN	0962-8452
NCID	AA00786976
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Author(s)
論文のバージョン	author
PubMed ID	36259204
DOI	10.1098/rspb.2022.1126
Web of Science KeyUT	000872392900003
関連URL	isVersionOf https://doi.org/10.1098/rspb.2022.1126

Salvage Surgery for Symptomatic Recurrence of Retro-Odontoid Pseudotumor after a C1 Laminectomy

JaLCDOI	10.18926/AMO/64127
フルテキストURL	76_6_749.pdf
著者	Takami, Masanari\| Yukawa, Yasutsugu\| Noda, Yusuke\| Yoshida, Munehito\| Yamada, Hiroshi\|
抄録	We provide the first report of successful salvage surgery for a post-C1 laminectomy symptomatic recurrence of a retro-odontoid pseudotumor (ROP) that caused myelopathy. The 72-year-old Japanese woman presented with an ROP causing symptomatic cervical myelopathy. With ultrasonography support, we performed the enucleation of the ROP via a transdural approach and fusion surgery for the recurrence of the mass. At the final observation 2-year post-surgery, MRI demonstrated the mass’s regression and spinal cord decompression, and the patient’s symptoms had improved. Our strategy is an effective option for a symptomatic recurrence of ROP.
キーワード	recurrent retro-odontoid pseudotumor salvage surgery transdural resection C1 laminectomy ultra-sonography
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2022-12
巻	76巻
号	6号
出版者	Okayama University Medical School
開始ページ	749
終了ページ	754
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	36549779
Web of Science KeyUT	000905195100017

Posterolateral Floating Technique for the Thoracic Ossification of the Posterior Longitudinal Ligament with Navigation: A Technical Note

JaLCDOI	10.18926/AMO/64126
フルテキストURL	76_6_743.pdf
著者	Tanaka, Masato\| Suthar, Hardik\| Desai, Dhvanit\| Yamauchi, Taro\| Arataki, Shinya\| Fujiwara, Yoshihiro\| Uotani, Koji\| Oda, Yoshiaki\| Misawa, Haruo\|
抄録	We describe a floating technique via a posterolateral approach with intraoperative O-arm navigation to facilitate decompression of the spinal cord in thoracic myelopathy due to severe ossification of the posterior longitudinal ligament (OPLL). A 62-year-old man with myelopathy due to thoracic OPLL had left-leg muscle weakness, urinary disturbance, and spastic gait. Bilateral leg pain and gait disturbance had persisted for 2 years. He was successfully treated by the posterolateral OPLL floating procedure and posterior pedicle fixation under O-arm navigation. At a 2-year follow-up, manual muscle testing results and sensory function of the left leg had recovered fully. His cervical Japanese Orthopedic Association score had improved from 5/12 to 11/12. The novel intraoperative O-arm navigation-guided posterolateral floating procedure for thoracic OPLL is effective for achieving precise decompression and strong fixation with a posterior approach only and can provide an excellent result for severe thoracic OPLL without the risk of adverse events from intraoperative radiation.
キーワード	ossification of the posterior longitudinal ligament floating method navigation surgery C-arm free
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2022-12
巻	76巻
号	6号
出版者	Okayama University Medical School
開始ページ	743
終了ページ	748
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	36549778
Web of Science KeyUT	000905195100016

Graphene Oxide-based Endodontic Sealer: An in Vitro Study

JaLCDOI	10.18926/AMO/64122
フルテキストURL	76_6_715.pdf
著者	Mohammed Zahedul Islam Nizami\| Gorduysus, Melahat\| Shinoda-Ito, Yuki\| Yamamoto, Tadashi\| Nishina, Yuta\| Takashiba, Shogo\| Arias, Zulema\|
抄録	The failure of endodontic treatment is directly associated with microbial infection in the root canal or periapical areas. An endodontic sealer that is both bactericidal and biocompatible is essential for the success of root canal treatments. This is one of the vital issues yet to be solved in clinical dental practice. This in vitro study assessed the effectiveness of graphene oxide (GO) composites GO-CaF2 and GO-Ag-CaF2 as endodontic sealer materials. Dentin slices were coated with either the GO-based composites or commonly used root canal sealers (non-eugenol zinc oxide sealer). The coated slices were treated in 0.9% NaCl, phosphate-buffered saline (PBS), and simulated body fluid (SBF) at 37˚C for 24 hours to compare their sealing effect on the dentin surface. In addition, the radiopacity of these composites was examined to assess whether they complied with the requirements of a sealer for good radiographic visualization. Scanning electron microscopy showed the significant sealing capability of the composites as coating materials. Radiographic images confirmed their radiopacity. Mineral deposition indicated their bioactivity, especially of GO-Ag-CaF2, and thus it is potential for regenerative application. They were both previously shown to be bactericidal to oral microbes and cytocompatible with host cells. With such a unique assemblage of critical properties, these GO-based composites show promise as endodontic sealers for protection against reinfection in root canal treatment and enhanced success in endodontic treatment overall.
キーワード	bioactive sealer graphene oxide mineral deposition antimicrobial activity radiopacity
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-12
巻	76巻
号	6号
出版者	Okayama University Medical School
開始ページ	715
終了ページ	721
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	36549774
Web of Science KeyUT	000905195100012