検索結果 6547 件
JaLCDOI | 10.18926/AMO/30569 |
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フルテキストURL | fulltext.pdf |
著者 | Itoo, Tei| |
抄録 | 1. Das pH des Blutes vom Hunde bleibt durch die Zufuhr von Cholsaure unverandert, wahrend die Alkalireserve dadurch erhoht wird. 2. Die experimentelle Ableitung der Galle nach aussen durch die Gallenblasenfistel fuhrt beim Hunde eine Herabsetzung von pH und der Alkalireserve des Blutes herbei. 3. Diese Herabsetzung von pH und der Alkalireserve des Blutes wird durch Wiederzufuhr von Cholsaure entweder wieder zum Anfangswerte hergestellt oder daruber hinaus gesteigert. 4. Das pH und die Alkalireserve des Blutes zeigen bei experimentellem St,auungsikterus einen mit der Zeit allmahlich gesteigerten Wert Aus diesen Ergebnissen geht hervor, dass der Gallensaureverlust aus dem Organismus die Acidosis hervorbringt, dagegen die uberschtissige Zufuhr von Gallensaure in den Organisrnus die Alkalosis herbeifuihrt. Auf Grund der Daten scheint mir die Gallensaure fur die Regulation der Wasserstoffionenkonzentration im Organismus eine gewisse Rolle zu spielen. |
Amo Type | Article |
出版物タイトル | Arbeiten aus der Medizinischen Universität zu Okayama |
発行日 | 1931-12 |
巻 | 2巻 |
号 | 4号 |
出版者 | Medizinische Universitat Okayama |
開始ページ | 372 |
終了ページ | 378 |
NCID | AA00508452 |
資料タイプ | 学術雑誌論文 |
言語 | ドイツ語 |
論文のバージョン | publisher |
査読 | 有り |
NAID | 120002305683 |
JaLCDOI | 10.18926/AMO/30568 |
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フルテキストURL | fulltext.pdf |
著者 | Itami, Kungo| Higashi, Saburo| |
抄録 | In Okara aus Sojabohnen findet sich eine antirachitisch wirkende Substanz, die zu dem unverseifbaren Teile gehort, Toriellii-Taffesche Reaktion ergibt und bei Verfutterung die Gallen und Gallensaureausscheidung des Hundes fordert. |
Amo Type | Article |
出版物タイトル | Arbeiten aus der Medizinischen Universität zu Okayama |
発行日 | 1931-12 |
巻 | 2巻 |
号 | 4号 |
出版者 | Medizinische Universitat Okayama |
開始ページ | 566 |
終了ページ | 571 |
NCID | AA00508452 |
資料タイプ | 学術雑誌論文 |
言語 | ドイツ語 |
論文のバージョン | publisher |
査読 | 有り |
NAID | 120002305563 |
JaLCDOI | 10.18926/AMO/30567 |
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フルテキストURL | fulltext.pdf |
著者 | Kimura, Ikuro| Yamana, Masatoshi| NNishishita, Akira| Sugiyama, Motoharu| Miyata, Akira| |
抄録 | A urinary iron excretion test was carried out in 22 patients with iron deficiency anemia. The iron excretion index was significantly higher in patients with intractable iron deficiency anemia compared with normal subjects and anemic patients who were responsive to iron therapy. The findings suggest that iron excretion may be a factor that modulates the response of patients to iron therapy. |
キーワード | iron excretion iron deficiency anemia saccharated iron oxide. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-02 |
巻 | 34巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 37 |
終了ページ | 41 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6446838 |
Web of Science KeyUT | A1980JS13800005 |
JaLCDOI | 10.18926/AMO/30566 |
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フルテキストURL | fulltext.pdf |
著者 | Miyamoto, Kanji| Miyano, Keiko| Miyoshi, Isao| Hamasaki, Kazuhide| Nishihara, Ryuji| Terao, Seiya| Kimura, Ikuro| Maeda, Kenichiro| Matsumura, Kazuyoshi| Mishijima, Katsumi| Tanaka, Toshio| |
抄録 | Cytogenetic studies were performed on a biopsy specimen of a jaw tumor and on a bone marrow aspirate from a Japanese patient with Epstein-Barr virus-negative Burkitt's lymphoma. A 14q + chromosome was found in cells from either source, although each contained a different clone. Other karyotypic abnormalities present in common included 2dir dup (1q) (q21 leads to q32), 3q+, 6p--, +12, +mar. |
キーワード | non-African Burkitt's lymphoma chromosome 14q+. |
Amo Type | Brief Note |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-02 |
巻 | 34巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 61 |
終了ページ | 65 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6446841 |
Web of Science KeyUT | A1980JS13800008 |
JaLCDOI | 10.18926/AMO/30565 |
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フルテキストURL | fulltext.pdf |
著者 | Hidaka, Hideyuki| Omura, Sachiko| Oda, Takuzo| |
抄録 | Several DNA-histone complexes were reconstituted in the presence and absence of urea. The fiber size of DNA-histone H1 complex was about 20 A in width with knobs 100 to 250 A in diameter interspersed at an average interval of about 1,100 A. H1-was associated with DNA segments corresponding to a DNA size of fewer than 100 base pairs. DNA-histones H2A, H2B, H3 and H4 complex consisted of globular subunits 100 to 150 A in diameter alternating with thin strands, like beads on a string. DNA-whole histones complex was 200 to 250 A in width and had a condensed configuration. The nuclease digestion pattern of the complexes containing histones H2A, H2B, H3 and H4 was regular, similar to that of chromatin, and was disrupted by urea. The complex containing H1 was inactive for in vitro RNA synthesis by escherichia coli RNA polymerase, whereas the other complexes were active. The complexes reconstituted in the absence of urea had template activities slightly less than in the presence of urea. |
キーワード | finestructure template activity DNA-histone complex reconstitution reconstitution electron microscopy nuclease digestion. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-02 |
巻 | 34巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 1 |
終了ページ | 10 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6446834 |
Web of Science KeyUT | A1980JS13800001 |
JaLCDOI | 10.18926/AMO/30564 |
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フルテキストURL | fulltext.pdf |
著者 | Kimura, Ikuro| Sugiyama, Motoharu| Ishibashi, Ken| Miyata, Akira| Matsuzaka, Hiroto| |
抄録 | The effect of desferrioxamine on several hematological parameters was studied in growing rats. Animals given desferrioxamine intramuscularly (150 mg/kg daily) had increased urinary iron after one week, and decreased hemoglobin after 2 weeks. The difference in hemoglobin concentration between the treated and control groups was significant after 4 weeks of treatment with desferrioxamine, but the difference in the numbers of erythrocytes was not significant. The anemia was of hypochromic type. Desferrioxamine at this dosage did not retard growth. These findings support our previously reported concept of "iron-losing anemia". |
キーワード | desferrioxamine iron excretion iron deficiency anemia. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-02 |
巻 | 34巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 31 |
終了ページ | 35 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6446837 |
Web of Science KeyUT | A1980JS13800004 |
JaLCDOI | 10.18926/AMO/30563 |
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フルテキストURL | fulltext.pdf |
著者 | Yamada, Teruo| Talbot, Alan| Hirakawa, Misahisa| Kobayashi, Naohide| Shiwaku, Yoshitomo| Kosaka, Futami| Kimoto, Tetsuo| |
抄録 | Renal cortex was studied during experimentally induced ischemia. A transient increase in anerobic glycolysis occurred with concomitant swelling of both the Golgi apparatus and mitochondria. These intracytoplasmic organelles underwent marked changes in their intracellular positions. Infolding of cytoplasmic membrane at the basal side of proximal tubule cells increased in complexity and proceeded to enclose various intracytoplasmic microorganelles such as mitochondria and the Golgi apparatus. Piling up in layers was particularly marked around mitochondria. This piling up appeared as myelin-like structures on the free surface of, and within, proximal tubule cells, and followed disruption of the brush border at the free surface. Histological examination of thin sections showed that the fused portions of this brush border were actually brush border cytoplasmic membrane piled up in layers giving the appearance of myelin-like structures. After two hours of ischemia, parts of the membrane of these myelin-like structures were disrupted. Large vacuoles developed and these were thought to be related to the large vacuoles seen during cell degeneration. |
キーワード | Myelin-like structures ischemia kidney |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-02 |
巻 | 34巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 19 |
終了ページ | 30 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6446836 |
Web of Science KeyUT | A1980JS13800003 |
JaLCDOI | 10.18926/AMO/30562 |
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フルテキストURL | fulltext.pdf |
著者 | Takaya, Yasumasa| Ota, Zensuke| Makino, Hirofumi| Kida, Keiko| Miyoshi, Akira| Hiramatsu, Makoto| Takahashi, Kayo| Ofuji, Tadashi| |
抄録 | Isolated and purified glomerular basement membranes (GBM) of normal and aminonucleoside (PAN) nephrosis rats were observed by electron microscopy after negative staining. Although GBM of normal rats appeared as a molecular sieve with uniform pores, GBM of nephrotic rats showed enlargement and elongation of the pores. For an average of fifty pores, the long dimension was 40.4+/-10.7 A and the short dimension 13.8+/-3.6 A in nephrosis whereas the long dimension was 12.3+/-2.5 A and the short dimension 8.4+/-1.0 A in normal rats. Changes in the pores in GBM were thought to result in increased permeability of serum protein and hence proteinuria. |
キーワード | gromerular basement membranc aminonucleoside nephrosis negative staining. |
Amo Type | Brief Note |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-02 |
巻 | 34巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 67 |
終了ページ | 70 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6446842 |
Web of Science KeyUT | A1980JS13800009 |
JaLCDOI | 10.18926/AMO/30561 |
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フルテキストURL | fulltext.pdf |
著者 | Miyoshi, Masanori| Nakashima, Yusaku| Hirakawa, Shuzo| Mitsunaga, Mikio| Nakagawa, Osamu| Miura, Hiroshi| Suzuki, Shinya| Ofuji, Tadashi| |
抄録 | Function of pituitary-thyroid axis was studied in rats with experimentally induced thyroiditisWistar strain female rats were immunized with homologous thyroid extract in Freund's complete adjuvant and with simultaneous intradermal injection of pertussis vaccine concentrate. They received booster shots at the first and third week after the initial immunization. Serum thyroid hormones and TSH were measured just before, and at weekly intervals after, the initial immunization. Histological examination of the thyroid gland at the second week after immunization showed slight infiltration of macrophages in the thyroid follicles. From the third to the fourth week, massive lymphoid cell infiltration and destruction of follicular architecture developed in all immunized rats. Serum R3 levels slightly decreased during the second week, increased transiently during the third week, then decreased again thereafter. Serum T4 levels decreased slightly durinf the fourth week. Serum TSH levels were not elevated significantly during the third week, but the response to TRH was significantly increased at this time. Basal TSH levels were increased during the fourth week. The TRH test was a sensitive method capable of detecting minimal failure of thyroid function undetected by other routine measuremens of thyroid hormones and TSH. |
キーワード | thyroid function thyrotropin (TSH) experimental thyroiditis thyroid hormones. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-02 |
巻 | 34巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 11 |
終了ページ | 17 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6446835 |
Web of Science KeyUT | A1980JS13800002 |
JaLCDOI | 10.18926/AMO/30560 |
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フルテキストURL | fulltext.pdf |
著者 | Tsuji, Takao| Inoue, Junichi| Shinohara, Toru| Tsuchiya, Masao| Onoue, Kimiaki| Araki, Kiyonori| Nagashima, Hideo| Nakashima, Akira| Naito, Kunihiko| |
抄録 | Fragmented sheep red blood cell (SRBC) membrane was used for detection of T-cells in liver biopsy specimens from patients with chronic active hepatitis. SRBC was separated with Lymphoprep, sonicated, then filtered through a 3 mu Millipore-membrane as a fragmented SRBC reagent. Tissue T-cells were stained by an indirect immunofluorescent technique using SRBC reagent and fluorescein isothiocyanate (FITC)-labelled rabbit anti-SRBC. Positively staining lymphocytes were present in portal tracts and in areas of piecemeal necrosis. There also seemed to be a positive correlation between the number of positively staining lymphocytes and the activity of chronic hepatitis; numerous lymphocytes being stained in areas of severe piecemeal necrosis. Our findings suggest that the fragmented SRBC technique for detection of T-cells is reliable and reproducible, that it could be used as a clinical routine method, and that it is useful for further elucidating the nature of host immune reactions on tissue levels.< |
キーワード | T-lymphocyte T-cell lymphocyte receptor chronic active hepatitis immune response. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-02 |
巻 | 34巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 51 |
終了ページ | 59 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6446840 |
Web of Science KeyUT | A1980JS13800007 |
JaLCDOI | 10.18926/AMO/30559 |
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フルテキストURL | fulltext.pdf |
著者 | Asahi, Toshihiko| Matsumura, Yosuke| Tanahashi, Toyoko| Yoshimoto, Jun| Kaneshige, Tetsuzo| Fujita, Yukitoshi| Ohmori, Hiroyuki| |
抄録 | Seventy-eight patients were treated with intravesical instillation of Thio-Tepa in an attempt to prevent postoperative recurrences of bladder tumors. Fifty-six patients who were given no preventive treatment against recurrences were taken as the control group. The patients in this series presented at the Okayama University Hospital between 1961 and 1976 and only the first recurrence after the primary operation was taken into consideration. There was no significant difference in the recurrence rates of the control and instillation groups. |
キーワード | bladder tumor intravesical instillation thiotepa recurrence rate. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-02 |
巻 | 34巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 43 |
終了ページ | 49 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6446839 |
Web of Science KeyUT | A1980JS13800006 |
JaLCDOI | 10.18926/AMO/30558 |
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フルテキストURL | fulltext.pdf |
著者 | Yamada, Gotaro| Takahashi, Takashi| Mizuno, Motowo| Sakamoto, Yuji| Kaga, Kazumi| Kobayashi, Toshinari| Nagashima, Hideo| |
抄録 | A recently modified method using peroxidase labeled antibodies for light and electron microscopic demonstration of hepatitis B virus (HBV) was applied to the evaluation of hepatitis B surface antigen (HBsAg) on the surface of liver cells in biopsy specimens from 24HBsAg chronic carriers. Membranous distribution of HBsAg was demonstrated in diffuse or scattered hepatocytes in all 4 asymptomatic carriers and in 3 of the 20 patients with HBsAg-positive chronic active hepatitis or liver cirrhosis. In these patients with membranous expression of HBsAg, hepatitis B e antigen, Dane particles and DNA polymerase were often detected in sera, and large amounts of hepatitis B core antigen appeared in the liver. These results suggest that membrane-bound HBsAg may be expressed by the HBV genome. The ultrastructural study of liver cells showing membranous expression disclosed dense deposits of reaction product indicative of HBsAg on the cell membrane and/or on assembled particles within the extracellular space. In some hepatocytes showing both diffuse cytoplasmic and membranous expression of HBsAg, HBsAg-positive membrane of cisternae open to the intercellular space was connected with the liver cell membrane. These findings supported the conjecture that HBV associated antigens are integrated into the liver cell membrane. |
キーワード | type B hepatitis membrane-bound HBsAg immunoelectron microscopy peroxidase-labeled antibody method. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-06 |
巻 | 34巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 175 |
終了ページ | 187 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6447986 |
Web of Science KeyUT | A1980KE59200005 |
JaLCDOI | 10.18926/AMO/30557 |
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フルテキストURL | fulltext.pdf |
著者 | Ymadada, Gotaro| Sakamoto, Yuji| Mizuno, Motowo| Kobayashi, Toshinari| Nagashima, Hideo| |
抄録 | In electron microscopic observation of a liver biopsy obtained from a hepatitis B surface antigen-positive patient, noncoated core particles were occasionally seen budding into the hepatocytic cisterni and many Dane particles were found in the pericanalicular vesicles of hepatocytes. Noncoated core particles were also localized in clusters within the bleb of microvilli. There were some core particles being protruded from microvilli into the lumen of bile canaliculi by budding. These findings suggest hepatitis B virus being released from the hepatocyte to the bile canaliculi by two different modes; through vesicle by reversed phagocytosis and from the microvilli by budding. |
キーワード | type B hepatitis hepatitis B virus Dane particle bile canaliculi. |
Amo Type | Brief Note |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-06 |
巻 | 34巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 203 |
終了ページ | 207 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6447989 |
Web of Science KeyUT | A1980KE59200008 |
JaLCDOI | 10.18926/AMO/30556 |
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フルテキストURL | fulltext.pdf |
著者 | Yoshioka, Junji| |
抄録 | Basilar arteries with experimental vasospasm were studies histochemically using a catecholamine fluorescence technique in 15 cats. Fluorescence microscopy of normal vessels revealed abundant catecholamine fluorescence in the adventitia and in close contact with the media, but none within the media. Experimental subarachnoid hemorrhage resulted in depletion of catecholamine fluorescence in the adventitia and in its appearance in the media. In vessels with vasospasm which lasted for 2 or 5 h and responded to vasodilators, fluorescence was scarce in the adventitia, but abundant in the media. In vessels with vasospasm unresponsive to spasmolytic agents, fluorescence was observed neither in the adventitia nor in the media. The results suggest that noradrenaline in the media of spastic arteries plays an important role in the development of cerebral vasospams. |
キーワード | cerebral vasospasm noradrenaline subarachnoid hemorrhage. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-06 |
巻 | 34巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 147 |
終了ページ | 153 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6447984 |
Web of Science KeyUT | A1980KE59200001 |
JaLCDOI | 10.18926/AMO/30555 |
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フルテキストURL | fulltext.pdf |
著者 | Hukuhara, Takesi| Neya, Toshiaki| Tsuchiya, Katsuhiko| |
抄録 | In guinea pigs the lumen of an excised jejunal segment was perfused to study the effect of intraluminal pressure on the frequency of rhythmic contraction waves. Within the range of 0 to 40 mmH2O, increases in intraluminal pressure caused increases in the frequency of contraction waves. At pressures of 10, 15, 20, 30 and 40 mmH2O the frequency was 7.9, 9.0, 10.9, 12.5 and 13.3 per min (mean of ten preparations), respectively. An exponential relationship was proved to exist between the pressure and the frequency. |
キーワード | intestinal motility intrinsic reflex. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-06 |
巻 | 34巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 169 |
終了ページ | 174 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6447985 |
Web of Science KeyUT | A1980KE59200004 |
JaLCDOI | 10.18926/AMO/30554 |
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フルテキストURL | fulltext.pdf |
著者 | Tokiwa, Takayoshi| Nishiyama, Syoichi| Yoshimoto, Jun| Sato, Jiro| |
抄録 | A near diploid clone derived from a rat liver cell line was continuously treated with various concentrations of 3'-methyl-4-dimethylaminoazobenzene (3'-Me-DAB) in culture. By treatment with 2.8 micrograms/ml, cells with 41 chromosomes formed a mode and which then shifted to 39. The chromosome numbers of cells treated with 5.4 micrograms/ml were widely distributed at early stages, but later the mode shifted to hypotetraploid region. Untreated control cells were confirmed as near diploid. Increased plating efficiency by 3'-Me-DAB as well as the appearance of large sized colonies was obtained. The production of alpha-fetoprotein (AFP) by the cells was slightly enhanced by treatment with 3'-Me-DAB. The cells treated with and without 3'-Me-DAB did not produce any tumor in rats 6 months after their intraperitoneal injection. |
キーワード | 3'-Me-DAB liber cells chromosome numbers plating efficiency ?-fetoprotein. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-06 |
巻 | 34巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 161 |
終了ページ | 168 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6158258 |
Web of Science KeyUT | A1980KE59200003 |
JaLCDOI | 10.18926/AMO/30553 |
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フルテキストURL | fulltext.pdf |
著者 | Tsuji, Takao| Araki, Kiyonori| Inoue, Junichi| Onoue, Kimiaki| Tsuchiya, Masao| Shinohara, Toru| Nagashima, Hideo| Nakashima, Akira| Naito, Kunihiko| Arborgh, Bengt| |
抄録 | Immune complexes in liver specimens from 10 patients with chronic liver diseases [2 with chronic persistent hepatitis (CPH), 3 with chronic aggressive hepatitis (CAH) of moderate activity, 3 with CAH of severe activity, and 2 with liver cirrhosis] were examined by a technique of direct immunofluorescence using FITC-labelled human purified Clq (FITC-Clq). FITC-Clq bound to the nuclei of all cells in liver tissue. After DNase treatment, positive nuclei were absent, but positive staining with FITC-Clq remained in amorphous deposits and hepatic cell membranes in the areas of piecemeal necrosis of four CAH patients. Since FITC-Clq could not be demonstrated in the liver tissue of CPH and liver cirrhosis which contained no piecemeal necrosis, positive fluorescence in the liver of CAH patients was thought to indicate immune complexes bound to FITC-Clq. The fact that these positive substances, however, were few in number, may be the result of physiological mechanisms of immune clearance which rapidly eliminate immune complexes from the body. |
キーワード | immune complex chronic aggressive hepatitis Clq DNA Clq-binding test. |
Amo Type | Brief Note |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-06 |
巻 | 34巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 209 |
終了ページ | 216 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6447990 |
Web of Science KeyUT | A1980KE59200009 |
JaLCDOI | 10.18926/AMO/30552 |
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フルテキストURL | fulltext.pdf |
著者 | Mizuno, Motowo| Yamada, Gotaro| Sakamoto, Yuzi| Yumoto, Yasuhiro| Nagashima, Hideo| |
抄録 | Antibody to hepatitis B core antigen (anti-HBc) was measured by radioimmunoassay using CORAB (Abbott Laboratories) in 10 cases of chronic persistent hepatitis (CPH), 46 cases of chronic aggressive hepatitis (CAH), 33 cases of liver cirrhosis (LC) and 53 cases of hepatocellular carcinoma (HCC) in relation to hepatitis B surface antigen (HBsAg) and its antibody (anti-HBs). Ninety-eight point four percent of patients with HBsAg and 93.8% of patients with anti-HBs were positive for anti-HBc and the titers of anti-HBc in patients with HBsAg were significantly higher than those with anti-HBs. Thirty-five point five percent of patients negative for either HBsAg or anti-HBs were positive for anti-HBc. The titers of anti-HBc in patients with CPH, CAH and LC were relatively low, whereas 7 (46.8%) of the HCC patients negative for either HBsAg or anti-HBc had high titers of anti-HBc. The significance of the presence of anti-HBc alone is discussed. |
キーワード | anti-HBc HBsAg anti-HBs radioimmunoassay chronic liver disease. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-06 |
巻 | 34巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 155 |
終了ページ | 160 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6251699 |
Web of Science KeyUT | A1980KE59200002 |
JaLCDOI | 10.18926/AMO/30551 |
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フルテキストURL | fulltext.pdf |
著者 | Murao, Tsuyoshi| Toda, Kanji| Tomiyama, Yoshihisa| |
抄録 | A papillary (villous) adenoma of the duodenum was found in a 67-year-old male. Radiographic barium studies of the upper gastrointestinal tract revealed a tumor in the second portion of the duodenum. Biopsied specimens taken through a duodenofiberscope showed papillary adenoma. A partial duodenectomy with duodenojejunostomy was performed. The specimen was a pedunculated tumor measuring 3 X 2 X 1.5 cm. Histologically, the tumor was composed of villous and tubular arrangements of mucus-secreting columnar epithelial cells. A moderate number of entero-endocrine cells and a few Paneth cells were also noted. Forty-two other cases reported in Japan are briefly reviewed. |
キーワード | papillary adenoma villous adenoma duodenal tumor duodenum. |
Amo Type | Brief Note |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-06 |
巻 | 34巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 197 |
終了ページ | 201 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6447988 |
Web of Science KeyUT | A1980KE59200007 |
JaLCDOI | 10.18926/AMO/30550 |
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フルテキストURL | fulltext.pdf |
著者 | Shigenobu, Masaharu| Suzuki, Yoshihide| Sato, Junichi| Sadakane, Shoji| Maeda, Naotoshi| Sano, Shunji| Yamamoto, Mitsuo| Kurahara, Hideki| Teramoto, Shigeru| |
抄録 | In the aortic stenosis group, the left ventricular (LV) muscle mass index was a good parameter for predicting the prognosis. Associated mitral valve disease had no influence on long term survival after aortic valve replacement. In the aortic insufficiency group, associated mitral valve disease had a marked influence on the results of aortic valve replacement. In general, the aortic insufficiency group had less clinical improvement postoperatively than the aortic stenosis group. In the annuloaortic ectasia group, left ventricular enddiastolic pressure (LVEDP) might be the predictor to the prognosis. This group had the worst prognosis, of the three groups. Early operation should be considered for patients who have no, or only mild symptoms of, aortic valve disease. |
キーワード | aortic valve replacement late survival predictor aoetic stenosis aortic insufficiency annuloaortic ectasia. |
Amo Type | Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 1980-06 |
巻 | 34巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 189 |
終了ページ | 196 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 6447987 |
Web of Science KeyUT | A1980KE59200006 |