ID | 63479 |
フルテキストURL | |
著者 |
Hamada, Kenta
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kanzaki, Hiromitsu
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
publons
researchmap
Miyahara, Koji
Department of Internal Medicine, Hiroshima City Hospital
Nakagawa, Masahiro
Department of Internal Medicine, Hiroshima City Hospital
Mouri, Hirokazu
Department of Gastroenterology and Hepatology, Kurashiki Central Hospital
Mizuno, Motowo
Department of Gastroenterology and Hepatology, Kurashiki Central Hospital
Takahashi, Sakuma
Department of Gastroenterology, Kagawa Prefectural Central Hospital
Hori, Shinichiro
Department of Endoscopy, National Hospital Organization Shikoku Cancer Center
Nasu, Junichiro
Department of Internal Medicine, Okayama Saiseikai General Hospital
Tsuzuki, Takao
Department of Internal Medicine, Japanese Red Cross Society Himeji Hospital
Miyaike, Jiro
Department of Internal Medicine, Saiseikai Imabari Hospital
Takenaka, Ryuta
Department of Internal Medicine, Tsuyama Chuo Hospital
Yamauchi, Kenji
Department of Gastroenterology, Mitoyo General Hospital
Kobayashi, Sayo
Department of Internal Medicine, Fukuyama City Hospital
Toyokawa, Tatsuya
Department of Gastroenterology, National Hospital Organization Fukuyama Medical Center
Inoue, Masafumi
Department of Gastroenterology, Japanese Red Cross Okayama Hospital
Nishimura, Mamoru
Department of Internal Medicine, Okayama City Hospital
Matsubara, Minoru
Department of Internal Medicine, Sumitomo Besshi Hospital
Tomoda, Jun
Department of Internal Medicine, Akaiwa Medical Association Hospital
Yamasaki, Yasushi
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
Kaken ID
publons
Tanaka, Takehiro
Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
Kaken ID
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Shirakawa, Yasuhiro
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
Kaken ID
publons
Kawahara, Yoshiro
Department of Practical Gastrointestinal Endoscopy, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kaken ID
researchmap
Fujiwara, Toshiyoshi
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
Kaken ID
publons
researchmap
Okada, Hiroyuki
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kaken ID
publons
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Okayama Gut Study Group
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抄録 | Objective Although Barrett's adenocarcinoma (BA) remains a minor disease in Japan, its incidence has been gradually increasing. We analyzed the characteristics of BA in Japanese populations.
Methods We retrospectively reviewed medical records and analyzed the clinicopathological differences between short-segment Barrett's esophagus (SSBE) and long-segment Barrett's esophagus (LSBE), as well as metastasis. Local recurrence and metachronous lesions were analyzed only in patients who underwent endoscopic resection (ER). Patients Consecutive patients who had pathological T1 BAs resected by ER or surgery from January 2003 Results A total of 168 patients were analyzed, including 139 with SSBE and 29 with LSBE. In total, 67% of the SSBE lesions and 32% of the LSBE lesions were located between 0 and 3 o'clock (p=0.0014). No patients who achieved pathological margin-free resection (pR0) and 17% of patients who did not achieve pR0 experienced local recurrence (p=0.0131). None of the patients without lymphovascular involvement, a poorly differentiated component, lesion size of >30 mm, and submucosal invasion of >500 mu m experienced metastasis. The 5-year cumulative incidence rate of metachronous BA after ER was 0% in patients with SSBE and 40% in patients with LSBE (p=0.0005). Conclusion Superficial BA was likely to be detected at the right anterior wall of SSBE in the Japanese population. The risk for metachronous BA after ER was high in Japanese patients with LSBE, as in Western patients. |
キーワード | Barrett's adenocarcinoma
endoscopic resection
long -segment Barrett's esophagus
metachronous
lesion
short -segment Barrett's esophagus
surgery
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発行日 | 2022-04-15
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出版物タイトル |
INTERNAL MEDICINE
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巻 | 61巻
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号 | 8号
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出版者 | The Japanese Society of Internal Medicine
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開始ページ | 1115
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終了ページ | 1123
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ISSN | 0918-2918
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | © 2022 The Japanese Society of Internal Medicine
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論文のバージョン | publisher
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.2169/internalmedicine.6942-20
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ライセンス | https://creativecommons.org/licenses/by-nc-nd/4.0/
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