ID | 32860 |
JaLCDOI | |
フルテキストURL | |
著者 |
Ogata, Sho
Department of Pathology and Laboratory Medicine, National Defense Medical College
Kimura, Akifumi
Department of Surgery III, National Defense Medical College
Hatsuse, Kazuo
Department of Surgery III, National Defense Medical College
Yamamoto, Junji
Department of Surgery III, National Defense Medical College
Shimazaki, Hideyuki
Department of Laboratory Medicine, National Defense Medical College
Nakanishi, Kuniaki
Department of Pathology and Laboratory Medicine, National Defense Medical College
Kawai, Toshiaki
Department of Pathology and Laboratory Medicine, National Defense Medical College
|
抄録 | Poorly differentiated adenocarcinoma without papilla or tubule formation of the extrahepatic bile duct is rare. Here we present a case (a 42-year-old Japanese woman) without either pancreatobiliary maljunction or liver disease. The patient had obstructive jaundice. Imaging studies revealed a bile duct tumor obstructing the common bile duct and invading the surrounding tissues. Pathologic examination revealed a dense periductal growth of poorly differentiated adenocarcinoma containing signet-ring cells, but without papilla or tubule formation in the extrahepatic bile duct. The tumor cells directly invaded the pancreatic parenchyma and the portal vein. In the extrahepatic bile duct, poorly differentiated adenocarcinoma may be established as a distinct clinicopathologic entity if the tumors are characterized by:1) the absence of papilla or tubule formation, 2) Asian preponderance, 3) occurrence at a younger age than is usual for patients with biliary cancers, and 4) an aggressive mural invasiveness. |
キーワード | adenocarcinoma
bile duct cancer
signet-ring cell carcinoma
|
Amo Type | Case Report
|
出版物タイトル |
Acta Medica Okayama
|
発行日 | 2010-02
|
巻 | 64巻
|
号 | 1号
|
出版者 | Okayama University Medical School
|
開始ページ | 63
|
終了ページ | 65
|
ISSN | 0386-300X
|
NCID | AA00508441
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
論文のバージョン | publisher
|
査読 |
有り
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PubMed ID | |
Web of Science KeyUT |