| JaLCDOI | 10.18926/AMO/57712 |
|---|---|
| フルテキストURL | 73_6_487.pdf |
| 著者 | Kishimoto, Fumiko| Fujii, Chiaki| Okanouchi, Toshio| Ohtsuki, Hiroshi| |
| 抄録 | We used spectral-domain optical coherence tomography (SD-OCT) to compare the foveal and parafoveal structures of 19 subjects aged 16-58 years (8 men, 11 women): 6 amblyopic patients with eccentric fixation, 5 amblyopic patients with central fixation, and 8 visually normal controls. We obtained foveal horizontal line scans using SD-OCT on all of the patients and controls. The total and layer thicknesses at foveal areas were analyzed. The mean (SD) ages of individuals in the eccentric fixation, central fixation, and control groups were 43.0 (13.9), 42.2 (16.3), and 38.5 (15.5) years, respectively. We observed no significant differences in the foveal or parafoveal retinal thicknesses at 500 and 1,500 μm from the foveal center among the 3 groups or between the amblyopic and fellow eyes. No significant differences were observed in the thickness of the ganglion cell complex layer or outer retinal layer at 500 and 1,500 μm from the foveal center among the three groups or between the two eyes. Overall, our SD-OCT analyses revealed no characteristic structural change in foveal regions in amblyopic eyes irrespective of the fixation behavior. |
| キーワード | foveal structure strabismic amblyopia optical coherence tomography eccentric fixation |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-12 |
| 巻 | 73巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 487 |
| 終了ページ | 494 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31871330 |
| Web of Science KeyUT | 000503431400003 |
| JaLCDOI | 10.18926/AMO/57713 |
|---|---|
| フルテキストURL | 73_6_495.pdf |
| 著者 | Masuda, Shin| Furumatsu, Takayuki| Okazaki, Yoshiki| Kamatsuki, Yusuke| Okazaki, Yuki| Kodama, Yuya| Hiranaka, Takaaki| Nakata, Eiji| Ozaki, Toshifumi| |
| 抄録 | Medial meniscus posterior root tear causes rapid knee cartilage degradation by inducing posteromedial displacement of the medial meniscus. We evaluated medial meniscus posterior extrusion before and after pullout repair for medial meniscus posterior root tear using magnetic resonance images. Twenty-eight patients with symptomatic medial meniscus posterior root tear were included. The inclusion criteria were: acute (< 3 months) or chronic (≥3 months) medial meniscus posterior root tear after painful popping events. The exclusion criteria were: other meniscus and anterior cruciate ligament injuries. We measured medial meniscus posterior extrusion and medial meniscus anteroposterior interval at knee flexion angles of 10° and 90° preoperatively and at 3 months postoperatively. The posterior extrusion at 90° knee flexion decreased from 4.42±1.38 mm preoperatively to 3.09±1.06 mm (p<0.001) postoperatively, while at 10° knee flexion it was −4.17±1.63 mm preoperatively and −3.77±1.72mm postoperatively, showing no significant change. The anteroposterior interval at 10° knee flexion increased from 19.74±4.27 mm preoperatively to 22.15±5.10 mm postoperatively (p<0.001); at 90° knee flexion, it increased from 16.81±4.51 mm preoperatively to 19.20±4.30 mm postoperatively (p<0.001). Medial meniscus posterior extrusion and movement decreased after pullout repair. Pullout repair for medial meniscus posterior root tear improves medial meniscus posterior extrusion, especially at 90° knee flexion. |
| キーワード | medial meniscus posterior root tear pullout repair extrusion open magnetic resonance imaging |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-12 |
| 巻 | 73巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 495 |
| 終了ページ | 501 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31871331 |
| Web of Science KeyUT | 000503431400004 |
| JaLCDOI | 10.18926/AMO/57714 |
|---|---|
| フルテキストURL | 73_6_503.pdf |
| 著者 | Kamatsuki, Yusuke| Furumatsu, Takayuki| Miyazawa, Shinichi| Kodama, Yuya| Hino, Tomohito| Okazaki, Yoshiki| Masuda, Shin| Okazaki, Yuki| Noda, Tomoyuki| Yamakawa, Yasuaki| Tetsunaga, Tomoko| Ozaki, Toshifumi| |
| 抄録 | Clinical studies have demonstrated that transtibial pullout repair led to favorable midterm outcomes in patients with medial meniscus posterior root tears (MMPRTs) although medial meniscal extrusion (MME) continued to be present. It has been unclear whether these residual postoperative MMEs existed after the pullout repair or had progressed at the very short-term evaluation after surgery. We sought to determine which characteristics of patients with MMPRTs influence the incidence of postoperative MME. The cases of 23 patients whose date of injury was known were analyzed. All patients underwent MMPRT pullout fixation. Preoperative and 3-month postoperative magnetic resonance imaging (MRI) examinations were performed. MME was retrospectively assessed on the mid-coronal plane of MRI scans. The preoperative and postoperative MME values were 4.2±1.2 mm and 4.3±1.5 mm, respectively (p=0.559). Pullout repair surgery was performed significantly earlier after the MMPRT-specific injury in patients whose postoperative MME improved compared to the patients whose MME did not improve (p<0.001). Our findings demonstrated that an early transtibial pullout repair of an MMPRT was more effective in reducing MME than a late repair. Surgeons should not miss the optimal timing for the pullout repair of an MMPRT, considering the period from the injury and the preoperative MME. |
| キーワード | medial meniscus posterior root tear pullout repair medial meniscus extrusion magnetic resonance imaging |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-12 |
| 巻 | 73巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 503 |
| 終了ページ | 510 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31871332 |
| Web of Science KeyUT | 000503431400005 |
| JaLCDOI | 10.18926/AMO/57715 |
|---|---|
| フルテキストURL | 73_6_511.pdf |
| 著者 | Takahara, Yasuhiro| Furumatsu, Takayuki| Nakashima, Hirotaka| Itani, Satoru| Nakamura, Makoto| Uchida, Yoichiro| Kato, Hisayoshi| Tsujimura, Yoshitaka| Iwasaki, Yuichi| Ochi, Nobuaki| |
| 抄録 | Medial open- and lateral closed-wedge high tibial osteotomy (hybrid CWHTO) can overcome the limitations of conventional CWHTO and open-wedge HTO (OWHTO) for medial compartmental osteoarthritis (OA) of the knee. Hybrid CWHTO increases stability by using a rigid locking plate and allows early full weight-bearing. However, the literature contains no information about time to bone union after this new procedure. The aim of this study is to evaluate the time to bone union after hybrid CWHTO. We reviewed 44 knees treated with hybrid CWHTO. Patients were able to stand on both legs on the day after surgery and walked with full weight-bearing within 4 weeks of the procedure. The time to achievement of bone union at the osteotomy site was defined as the number of months until bone union was confirmed on radiographic imaging. The mean time to radiographic confirmation of bone union was 4.5±1.5 months after surgery. Eleven knees (25.0%) required 6 months or more. Radiographic analysis and JOA score improved significantly between before and 1 year after surgery (p<0.01). Hybrid CWHTO is a very useful method for treating medial OA, but radiographic bone union requires 4.5 months on average. We must be aware of bone union after hybrid CWHTO. |
| キーワード | bone union hybrid closed-wedge high tibial osteotomy osteoarthritis |
| Amo Type | Original Article |
| 備考 | ,| |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-12 |
| 巻 | 73巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 511 |
| 終了ページ | 516 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31871333 |
| Web of Science KeyUT | 000503431400006 |
| JaLCDOI | 10.18926/AMO/57716 |
|---|---|
| フルテキストURL | 73_6_517.pdf |
| 著者 | Hosogi, Mika| Shiode, Yusuke| Morizane, Yuki| Kimura, Shuhei| Hosokawa, Mio| Doi, Shinichiro| Toshima, Shinji| Takahashi, Kosuke| Fujiwara, Atsushi| Shiraga, Fumio| |
| 抄録 | We investigated the effectiveness of a treat-and-extend regimen (TAE) of intravitreal ranibizumab injections for macular edema (ME) due to branch retinal vein occlusion (BRVO). We retrospectively examined 2-year results of 32 eyes of 32 patients who underwent TAE to treat ME due to BRVO. The patients whose treatment interval extended to ≥ 12 weeks were switched to a pro re nata regimen (PRN). For the patients whose treatment interval was <12 weeks, TAE was continued. At 2 years, 10 eyes had required no additional injections after the initial treatment period [recurrence(−) group], whereas the other 22 eyes required additional treatment [recurrence(+) group]. Among the recurrence(+) patients, 11 eyes (34.4% of total) were eventually switched from TAE to PRN; the other 11 eyes (34.4%) continued TAE for 2 years. Visual acuity and central retinal thickness were significantly improved in both the recurrence(+) and (−) groups, and there was no significant betweengroup difference in visual acuity at 2 years. Univariate analyses revealed significant differences in visual acuity (p=0.004), age (p=0.014), and vessel occlusion site (p=0.018) between these groups. Our results suggest that TAE may be effective for BRVO patients with lower visual acuity, older age, and occlusion of a major vein. |
| キーワード | branch retinal vein occlusion macular edema anti-vascular endothelial growth factor ranibizumab treat-and-extend regimen |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-12 |
| 巻 | 73巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 517 |
| 終了ページ | 522 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31871334 |
| Web of Science KeyUT | 000503431400007 |
| JaLCDOI | 10.18926/AMO/57717 |
|---|---|
| フルテキストURL | 73_6_523.pdf |
| 著者 | Hiranaka, Takaaki| Furumatsu, Takayuki| Okazaki, Yoshiki| Kamatsuki, Yusuke| Masuda, Shin| Okazaki, Yuki| Takihira, Shota| Miyazawa, Shinichi| Nakata, Eiji| Ozaki, Toshifumi| |
| 抄録 | The case of an individual with a bilateral anterior cruciate ligament (ACL) tear combined with a medial meniscus (MM) posterior root tear is described. A 34-year-old Japanese man with bilateral ACL rupture that occurred > 10 years earlier was diagnosed with bilateral ACL tear combined with MM posterior root tear (MMPRT). We performed a transtibial pullout repair of the MMPRT with ACL reconstruction. The tibial tunnels for the MM posterior root repair and ACL reconstruction were created separately. Postoperatively, a good clinical outcome and meniscal healing were obtained. Our surgical technique may thus contribute to anatomical MM posterior root repair and ACL reconstruction. |
| キーワード | bilateral anterior cruciate ligament tear medial meniscus posterior root tear pullout repair case report |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-12 |
| 巻 | 73巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 523 |
| 終了ページ | 528 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31871335 |
| Web of Science KeyUT | 000503431400008 |
| JaLCDOI | 10.18926/AMO/57718 |
|---|---|
| フルテキストURL | 73_6_529.pdf |
| 著者 | Kitayama, Takahiro| Akaki, Shiro| Hisazumi, Kento| Yoshio, Kotaro| Inoue, Daisaku| Tajiri, Nobuhisa| Shiode, Tsuyoki| Kanazawa, Susumu| Fujimoto, Shohei| Kanai, Kengo| Hirata, Yuji| |
| 抄録 | Nasal chondromesenchymal hamartoma (NCMH), a rare, benign, nasal cavity tumor, typically occurs in children. Differential diagnosis is difficult because NCMH often presents with non-specific findings, including cystic components and invasion of the surrounding area on T2-weighted magnetic resonance images. Here, we present a rare adult case of NCMH, with no clear hyperintensity on diffusion-weighted images (DWI), and bone remodeling on the tumor margins on computed tomography. To the best of our knowledge, this is the first report of DWI on NCMH, and these findings, which suggest benign disease, may be useful in diagnosing NCMH. |
| キーワード | nasal chondromesenchymal hamartoma computed tomography magnetic resonance imaging diffusion-weighted imaging |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-12 |
| 巻 | 73巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 529 |
| 終了ページ | 532 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31871336 |
| Web of Science KeyUT | 000503431400009 |
| JaLCDOI | 10.18926/AMO/57719 |
|---|---|
| フルテキストURL | 73_6_533.pdf |
| 著者 | Morimoto, Yusuke| Tokuhashi, Yasuaki| |
| 抄録 | The patient was a 40-year-old female who had been treated at our hospital for left peroneal tendonitis due to an ankle sprain 2 years earlier. She re-injured that ankle while dancing. The pain in the lateral left foot soon improved, but she had difficulty standing with the left foot in equinus. Complete peroneus longus and brevis tendon ruptures were diagnosed. The ipsilateral semitendinosus and gracilis tendons were harvested and used to reconstruct the tendons. Three months after surgery, the patient was able to stand in equinus, and at 5 months after surgery she resumed her original level of sports activities. |
| キーワード | peroneus longus and brevis complete rupture reconstruction hamstring tendon tendon grafting |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-12 |
| 巻 | 73巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 533 |
| 終了ページ | 536 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31871337 |
| Web of Science KeyUT | 000503431400010 |
| JaLCDOI | 10.18926/AMO/57720 |
|---|---|
| フルテキストURL | 73_6_537.pdf |
| 著者 | Takahara, Yasuhiro| Nishida, Keiichiro| Nakashima, Hirotaka| Ochi, Nobuaki| Uchida, Yoichiro| Kato, Hisayoshi| Itani, Satoru| Nakamura, Makoto| Iwasaki, Yuichi| Tsujimura, Yoshitaka| |
| 抄録 | High tibial osteotomy (HTO) procedure is generally contraindicated in rheumatoid arthritis (RA) patients because synovial inflammation may exacerbate joint damage post-surgery. The natural course of joint destruction in RA changed dramatically with new treatment strategies and the introduction of biologic disease-modifying anti-rheumatic drugs (bDMARDs). We report the cases of two RA patients who underwent HTO and whose disease activities were well controlled by bDMARDs. Despite their short follow-up periods, they showed acceptable objective and subjective clinical results. We believe that the combination of bDMARDs and HTO can be indicated for selected RA patients before total knee arthroplasty. |
| キーワード | high tibial osteotomy rheumatoid arthritis biologic DMARD knee surgery |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-12 |
| 巻 | 73巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 537 |
| 終了ページ | 542 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31871338 |
| Web of Science KeyUT | 000503431400011 |
| JaLCDOI | 10.18926/AMO/57721 |
|---|---|
| フルテキストURL | 73_6_543.pdf |
| 著者 | Kubo, Asuka| Shimizu, Kazuyoshi| Kuroda, Kosuke| Kanazawa, Tomoyuki| Kobayashi, Motomu| Morimatsu, Hiroshi| |
| 抄録 | We here report that a 71-year-old Japanese woman with a history of anaphylaxis induced by muscle relaxants had local anesthetic systemic toxicity (LAST) following an abdominal surgery under general anesthesia with combined spinal-epidural anesthesia without muscle relaxants. The total dosages of local anesthetics reached 0.67 mg/kg of ropivacaine and 11.5 mg/kg of lidocaine over 12.5 h to obtain sufficient muscle relaxation for surgery. Regional anesthesia is useful in cases in which muscle relaxants are to be avoided during a surgery. However, especially for a patient with risk factors and prolonged surgery, precautions should be taken to prevent LAST. |
| キーワード | muscle relaxant-induced anaphylaxis local anesthetic systemic toxicity epidural anesthesia abdominal surgery |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-12 |
| 巻 | 73巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 543 |
| 終了ページ | 546 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31871339 |
| Web of Science KeyUT | 000503431400012 |
| JaLCDOI | 10.18926/AMO/57722 |
|---|---|
| フルテキストURL | 73_6_547.pdf |
| 著者 | Yokoyama, Akihiro| Kada, Akiko| Saito, Akiko M.| Sawamura, Morio| Komeno, Takuya| Sunami, Kazutaka| Takezako, Naoki| |
| 抄録 | Elderly multiple myeloma (MM) patients, who are generally ineligible for transplantation, have high risks of death and treatment discontinuation, and require a regimen incorporating novel agents that balance safety, tolerability, and efficacy. We evaluated alternating bortezomib-dexamethasone and lenalidomide-dexamethasone treatments administered over a 63-day cycle in transplant-ineligible elderly patients with newly diagnosed MM. Subcutaneous bortezomib 1.3 mg/m2 was administered weekly on Days 1, 8, 15, and 22; oral lenalidomide 15 mg daily on Days 36-56; and oral dexamethasone 20 mg on Days 1, 8, 15, 22, 36, 43, 50, and 57 for 6 cycles. The primary endpoint was the overall response rate. |
| キーワード | bortezomib lenalidomide dexamethasone myeloma |
| Amo Type | Clinical Study Protocol |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-12 |
| 巻 | 73巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 547 |
| 終了ページ | 552 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31871340 |
| Web of Science KeyUT | 000503431400013 |
| JaLCDOI | 10.18926/AMO/57946 |
|---|---|
| フルテキストURL | 74_1_1.pdf |
| 著者 | Chen, Yuehua| Ohara, Toshiaki| Xing, Boyi| Qi, Jiping| Noma, Kazuhiro| Matsukawa, Akihiro| |
| 抄録 | Iron is a trace but vital element in the human body and is necessary for a multitude of crucial processes in life. However, iron overload is known to induce carcinogenesis via oxidative stress. Cancer cells require large amounts of iron for their rapid division and cell growth. Iron was recently found to play a role in cancer stem cells (CSCs); it maintains stemness during development. Iron also plays an important role in stemness by moderating reactive oxygen species. Thus, iron metabolism in CSCs is a promising therapeutic target. In this review, we summarize the roles of iron in cancer cells and CSCs. We also summarize anti-cancer therapeutic studies with iron chelators and describe our expectation of a new therapeutic strategy for CSCs on the basis of our findings. |
| キーワード | cancer stem cell stemness iron chelation chemotherapy |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-02 |
| 巻 | 74巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 1 |
| 終了ページ | 6 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32099242 |
| Web of Science KeyUT | 000516606200001 |
| NAID | 120006795613 |
| JaLCDOI | 10.18926/AMO/57947 |
|---|---|
| フルテキストURL | 74_1_7.pdf |
| 著者 | Sanki, Tomoaki| Endo, Hirosuke| Tetsunaga, Tomonori| Furumatsu, Takayuki| Yamada, Kazuki| Ozaki, Toshifumi| |
| 抄録 | We investigated the relationship between the initial contact status and stress shielding in total hip arthroplasty (THA) using fit-and-fill type straight-stem implants. In addition we evaluated the clinical and radiographic outcomes. Subjects were 100 hips of 94 patients who underwent THA and were followed-up for ≥10 years. Contact areas with the femoral cortical bone were investigated according to the zonal distribution of Gruen using postoperative CT images. Depending on the number of contact areas, the patients were classified into high contact [HC], medium contact [MC], and low contact [LC] groups. Radiographic and clinical outcomes were evaluated. In the HC group (20 hips), severe stress shielding was observed in 12 hips, which was statistically significant (p=0.008). In the LC group (29 hips), mild stress shielding was observed in 27 hips which was statistically significant (p<0.001). No significant differences were observed among the 3 groups in clinical outcomes, Harris hip score (p=0.719) or Japanese Orthopedic Association (JOA) score (p=0.301). In insertion of cementless collared fit-and-fill type straight-stem implants, severe late stress shielding of the femoral bone may occur if high contact of the femoral component is achieved. However, the degree of stress shielding does not result in adverse clinical outcomes. |
| キーワード | fit-and-fill stress shielding cementless straight stem total hip arthroplasty |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-02 |
| 巻 | 74巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 7 |
| 終了ページ | 15 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32099243 |
| Web of Science KeyUT | 000516606200002 |
| NAID | 120006795614 |
| JaLCDOI | 10.18926/AMO/57948 |
|---|---|
| フルテキストURL | 74_1_17.pdf |
| 著者 | Ishii, Kenzo| Morimatsu, Hiroshi| Ono, Kazumi| Miyasho, Koji| |
| 抄録 | We performed a retrospective cohort study of 911 high-energy trauma patients who underwent chest CT scans at least twice after admission. We hypothesized that in high-energy trauma patients, a high-inspired oxygen concentration delivered after admission results in dorsal atelectasis. The study’s primary outcome was dorsal atelectasis formation diagnosed based on CT images. We defined dorsal atelectasis as the presence of atelectasis at ≥ 10 mm thick on CT images. We defined high-inspired oxygen concentration as >60% oxygen delivered between two CT scans. Four hundred sixty-five patients (51.0%) developed atelectasis according to the second CT scan, and 338 (37.1%) received a high-inspired oxygen concentration. A univariate analysis showed that the rate of the high-inspired oxygen concentration in the atelectasis group was significantly higher than that in the non-atelectasis group (43.4% vs. 30.1%, p<0.001). However, a logistic regression analysis showed that there was no significant relationship between the oxygen concentration and the formation of dorsal atelectasis (OR: 1.197, 95%CI: 0.852-1.683, p=0.30). Age, the Injury Severity Score, BMI, and smoking were found to be risk factors of dorsal atelectasis formation in high-energy trauma patients. There was no relationship between the oxygen concentration and atelectasis formation in our series of high-energy trauma patients. |
| キーワード | trauma patient dorsal atelectasis oxygen concentration |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-02 |
| 巻 | 74巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 17 |
| 終了ページ | 26 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32099244 |
| Web of Science KeyUT | 000516606200003 |
| NAID | 120006795615 |
| JaLCDOI | 10.18926/AMO/57949 |
|---|---|
| フルテキストURL | 74_1_27.pdf |
| 著者 | Toda, Kazukiyo| Yagata, Yukihisa| Kikuchi, Takeshi| Takigawa, Tomoyuki| Ito, Yasuo| |
| 抄録 | Pelvic fractures occur with high-energy trauma, and the patient’s clinical status is unstable. Although a number of surgical methods for unstable pelvic fractures are available, none can achieve strong fixation with minimal invasiveness. We describe a surgical transiliac rod and screw fixation (TIF) procedure that provides minimally invasive fixation using a spinal implant for unstable pelvic ring fractures, and we retrospectively analyzed the procedure’s outcomes in 27 patients with type B or C1 fractures (based on the AO/ATO classification system). Small skin incisions are made above the posterior superior iliac spines on both sides. The ilium is partially resected, and two iliac screws are inserted on each side. The spinous process of the sacral spine is then shaved, and the iliac screws are connected to 2 rods, one placed caudal to the other. Corrective manipulation is performed at the fracture site, and the rods are connected with connectors. Favorable fracture reduction, defined as a rating of ‘excellent’ or ‘good,’ was achieved in 77.8% of the patients. Transiliac rod and screw fixation (TIF) will be a useful therapeutic option for unstable pelvic ring fractures. |
| キーワード | pelvic ring fractures sacral fracture transiliac rod and screw fixation spinal fixation system minimally invasive surgery |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-02 |
| 巻 | 74巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 27 |
| 終了ページ | 32 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32099245 |
| Web of Science KeyUT | 000516606200004 |
| NAID | 120006795616 |
| JaLCDOI | 10.18926/AMO/57950 |
|---|---|
| フルテキストURL | 74_1_33.pdf |
| 著者 | Honda, Hiroyuki| Hanayama, Yoshihisa| Obika, Mikako| Hasegawa, Kou| Hamahara, Jun| Kishida, Masayuki| Hagiya, Hideharu| Ogawa, Hiroko| Kataoka, Hitomi| Otsuka, Fumio| |
| 抄録 | A relationship between diabetes and depression is apparent. To clarify the clinical relevance of diabetic patients’ gastroesophageal symptoms to their psychological status, we retrospectively analyzed the data from a Selfrating Depression Scale (SDS) and a Frequency Scale for Symptoms of Gastroesophageal reflux disease (FSSG) among 143 type 2 diabetic patients who visited a general medicine department. Among the 45 Japanese patients enrolled, the group with relatively high SDS scores (≥ 36) showed higher (FSSG) dysmotility symptom scores versus the low-SDS (< 36) group, although the 2 groups’ characteristics and laboratory data were not significantly different. Positive correlations of postprandial plasma glucose (PPG) levels with FSSG scores (R=0.321, p<0.05), particularly with reflux scores (R=0.455, p<0.01) were revealed. PPG and HbA1c levels were not correlated with SDS scores. The patients’ SDS scores were significantly correlated with their FSSG scores (R=0.41, p<0.01), suggesting that depressive status is linked to GERD-related manifestations. Considering that the patients’ PPG levels were correlated with GERD-related symptoms, diabetic patients’ blood glucose levels are associated with depressive status. Collectively, key symptoms related to GERD and glucose level values would be helpful |
| キーワード | blood glucose type 2 diabetes mellitus gastroesophageal reflux depressive status postprandial plasma glucose |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-02 |
| 巻 | 74巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 33 |
| 終了ページ | 40 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32099246 |
| Web of Science KeyUT | 000516606200005 |
| NAID | 120006795617 |
| JaLCDOI | 10.18926/AMO/57951 |
|---|---|
| フルテキストURL | 74_1_41.pdf |
| 著者 | Amano, Hoichi| Fujimoto, Kenichi| Fujimori, Makoto| Saka, Natsumi| Nomura, Kyoko| Tanihara, Shinichi| |
| 抄録 | We aimed to clarify the prevalence of polypharmacy among elderly individuals in Japan. We used the data obtained from a large-scale population-based representative database of health insurance claims in a single prefecture in Japan. We examined all of the outpatient and pharmaceutical health insurance claims for National Health Insurance and those for Late-stage Elderly Health Insurance in Nagasaki Prefecture, Japan between April and June 2016. When two or more claim forms were issued for a patient in a single month, we combined the data and identified the number of prescribed drugs for each person. The definition of polypharmacy is a the prescription of six or more drugs per month. We investigated the prevalence of polypharmacy among the beneficiaries of the two insurance systems. Of the 605,406 beneficiaries of the 2 insurance systems, 121,033 (20.0%) patients with polypharmacy were identified. The prevalence of polypharmacy increased with age, especially among the beneficiaries aged > 85 years, with about half of the beneficiaries having polypharmacy status. About half of the people aged > 85 years in the database had polypharmacy status. When a drug is prescribed to an elderly individual, it is necessary to consider the possibility of polypharmacy-related problems. |
| キーワード | health insurance claims late-stage elderly health insurance national health insurance Japan polypharmacy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-02 |
| 巻 | 74巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 41 |
| 終了ページ | 48 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32099247 |
| Web of Science KeyUT | 000516606200006 |
| NAID | 120006795618 |
| JaLCDOI | 10.18926/AMO/57952 |
|---|---|
| フルテキストURL | 74_1_49.pdf |
| 著者 | Takeuchi, Takashi| Okumura, Yasuyuki| Ichikura, Kanako| |
| 抄録 | The use of alcohol or drug(s) prior to self-injury is a possible inducing factor for suicidal self-injuries among patients with adjustment disorder. We analyzed the cases of 175 individuals who were admitted to the intensive care unit (ICU) of Tokyo Medical and Dental University Medical Hospital for suicidal self-injury to determine whether alcohol consumption or an excessive use of prescribed psychotropic medications prior to self-injury is more common in patients with adjustment disorder. During a 7-year period (July 2006 to June 2013) following their deliberate self-injuries, 971 patients were admitted to the ICU. Our study sample (n=175) was restricted to patients with adjustment disorder (n=48), major depressive disorder (n=90), or schizophrenia (n=37). The outcome variable was alcohol consumption or excessive use of medications prior to suicidal self-injury. A logistic regression analysis revealed that the patients with adjustment disorder more commonly showed alcohol consumption or excessive medication use prior to their suicidal self-injury compared to those with schizophrenia (odds ratio: 8.10; 95%CI: 2.97-24.60). To inhibit suicidal self-injury among patients with adjustment disorder, it is important to continue efforts to provide psychoeducation about alcohol use and to instruct the patients to take their prescribed medication(s) only as directed by their physician. |
| キーワード | alcohol psychotropic medications self-injury adjustment disorder |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-02 |
| 巻 | 74巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 49 |
| 終了ページ | 52 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32099248 |
| Web of Science KeyUT | 000516606200007 |
| NAID | 120006795619 |
| JaLCDOI | 10.18926/AMO/57953 |
|---|---|
| フルテキストURL | 74_1_53.pdf |
| 著者 | Kubota, Risa| Araki, Motoo| Wada, Koichiro| Kawamura, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Ariyoshi, Yuichi| Iwata, Takehiro| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Kano, Yuzuki| Kitagawa, Masashi| Tanabe, Katsuyuki| Sugiyama, Hitoshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 抄録 | We investigated the feasibility of robotic renal autotransplantation (RAT) in a porcine model to reduce invasiveness of RAT. Five pigs underwent robotic RAT using the da Vinci® robotic system. A robotic left nephrectomy was performed in all cases. Robotic RAT was performed on the left side in all but one case. Four ports were used. In 3 cases, the kidney was taken out through the GelPort® and irrigated on ice with Ringer’s solution. In 2 cases, a complete intracorporeal robotic RAT was performed. An end-to-side anastomosis was performed between the renal vein and the external iliac vein and between the renal artery and the external iliac artery. Ureteroneocystostomy was also performed in 2 cases. All cases were performed robotically without open conversion. The median (IQR) console time was 3.1 (0.7) h, and the operative time was 3.8 (1.1) h. The estimated blood loss was 30 (0) ml. The warm ischemia time was 4.0 (0.2) min, and the cold ischemia time was 97 (17) min. Intracorporeal transarterial hypothermic renal perfusion was feasible in the 2 complete intracorporeal robotic RAT cases by using a perfusion catheter through a laparoscopic port. Robotic RAT has the potential to be a new minimally invasive substitute for conventional open surgery. |
| キーワード | renal autotransplantation robotic porcine model transplantation |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-02 |
| 巻 | 74巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 53 |
| 終了ページ | 58 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32099249 |
| Web of Science KeyUT | 000516606200008 |
| NAID | 120006795620 |
| JaLCDOI | 10.18926/AMO/57954 |
|---|---|
| フルテキストURL | 74_1_59.pdf |
| 著者 | Owari, Yutaka| Miyatake, Nobuyuki| Suzuki, Hiromi| |
| 抄録 | Few studies have considered the causal relationship between psychological distress and social participation in elderly people. Here we investigated this relationship based on an initial survey and a follow-up survey. In 2016, a survey was distributed to 86 participants. A follow-up survey of 80 of those participants was performed in 2017. We adopted the following variables: psychological distress and social participation as represented by the Kessler psychological distress scale and social participation scores, respectively. By using cross-lagged and synchronous effects models, we found that the 2016 Kessler psychological distress scale had a significant influence on the 2017 social participation scores (standardization factor=−0.221, p=0.020) and the 2017 Kessler psychological distress scale significantly influenced the 2017 social participation scores (standardization factor=−0.345, p=0.039). The results suggest that psychological distress may affect social participation one year later. |
| キーワード | causal relationship elderly people psychological distress social participation structural equation modeling (SEM) |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-02 |
| 巻 | 74巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 59 |
| 終了ページ | 63 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32099250 |
| Web of Science KeyUT | 000516606200009 |
| NAID | 120006795621 |