ID | 31574 |
JaLCDOI | |
フルテキストURL | |
著者 |
Shinagawa, Katsuji
Second Department of Internal Medicine, Okayama University Medical School
Kaken ID
publons
researchmap
Imajo, Kenji
Second Department of Internal Medicine, Okayama University Medical School
Tada, Shinya
Second Department of Internal Medicine, Okayama University Medical School
Tsubota, Teruhiko
Second Department of Internal Medicine, Okayama University Medical School
Kimura, Ikuro
Second Department of Internal Medicine, Okayama University Medical School
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抄録 | The activity of pulmonary lymphocytes was evaluated by the detection of interleukin-2 (IL-2) receptor alpha mRNA expression in lung cancer patients associated with diffuse interstitial shadow on roentgenograms of their lungs. Reverse transcription coupled with the polymerase chain reaction was used to detect mRNA expression. In 5 of 6 patients, IL-2R alpha mRNA expression was increased in pulmonary lymphocytes compared with 4 normal controls. The expression in this mRNA in peripheral blood lymphocytes was almost undetectable in either normal controls or these patients. These results suggest that pulmonary lymphocytes in patients with lung cancer associated with diffuse interstitial shadows are activated and may promote the inflammatory process generating pulmonary fibrosis.
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キーワード | pulmonary fibrosis
lung cancer
pulmonary lymphocytes
IL-2R α mRNA
RT-PCR
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Amo Type | Article
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出版物タイトル |
Acta Medica Okayama
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発行日 | 1993-04
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巻 | 47巻
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号 | 2号
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出版者 | Okayama University Medical School
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開始ページ | 73
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終了ページ | 78
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | Copyright© 1999 Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID | |
Web of Science KeyUT | |
関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/5957
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