| JaLCDOI |
10.18926/AMO/60371
|
| フルテキストURL |
74_4_327.pdf
|
| 著者 |
Yamamoto, Ken-ichi|
Kagawa, Hiroko|
Arimoto, Sakae|
Tan, Xian Wen|
Yasui, Kento|
Oshiki, Toshiyuki|
Sakaguchi, Masakiyo|
|
| 抄録 |
An increasing accumulation of microplastics and further degraded nanoplastics in our environment is suspected to have harmful effects on humans and animals. To clarify this problem, we tested the cytotoxicity of two types of plastic wrap on human cultured liver cells and mouse primary cultured liver cells. Alcohol extracts from plastic wrap, i.e., polyvinylidene chloride (PVDC), showed cytotoxic effects on the cells. Alcohol extracts of polyethylene (PE) wrap were not toxic. The commercially available PVDC wrap consists of vinylidene chloride, epoxidized soybean oil, epoxidized linseed oil as a stiffener and stabilizer; we sought to identify which component(s) are toxic. The epoxidized soybean oil and epoxidized linseed oil exerted strong cytotoxicity, but the plastic raw material itself, vinylidene chloride, did not. Our findings indicate that plastic wraps should be used with caution in order to prevent health risks.
|
| キーワード |
plastic wrap
plasticizer,
cytotoxicity,
liver cells
in vitro
|
| Amo Type |
Original Article
|
| 出版物タイトル |
Acta Medica Okayama
|
| 発行日 |
2020-08
|
| 巻 |
74巻
|
| 号 |
4号
|
| 出版者 |
Okayama University Medical School
|
| 開始ページ |
327
|
| 終了ページ |
334
|
| ISSN |
0386-300X
|
| NCID |
AA00508441
|
| 資料タイプ |
学術雑誌論文
|
| 言語 |
英語
|
| 著作権者 |
CopyrightⒸ 2020 by Okayama University Medical School
|
| 論文のバージョン |
publisher
|
| 査読 |
有り
|
| PubMed ID |
32843764
|
| Web of Science KeyUT |
000562508700008
|
| NAID |
120006880210
|
