JaLCDOI 10.18926/AMO/54981
フルテキストURL 71_2_127.pdf
著者 Shirakawa, Yasuhiro| Noma, Kazuhiro| Maeda, Naoaki| Tanabe, Shunsuke| Kuroda, Shinji| Kagawa, Shunsuke| Katsui, Kuniaki| Katayama, Norihisa| Kanazawa, Susumu| Fujiwara, Toshiyoshi|
抄録 Currently, chemoradiation is the most widely used nonsurgical treatment for esophageal cancer. However, some patients, particularly the very elderly or those with severe vital organ dysfunction, face difficulty with the chemotherapy component. We therefore examined the outcome of radiation therapy (RT) alone for patients with esophageal cancer at our facility. Between January 2005 and December 2014, 84 patients underwent RT at our hospital, and 78 of these patients received concomitant chemotherapy. The remaining 6 patients underwent RT alone; these patients were considered to be high-risk and to have no lymph node metastasis (stage I). Five of them received irradiation up to a curative dose: 4 showed a complete response (CR) and 1 showed a partial response (PR). Of the patients exhibiting CR, 3 are currently living recurrence-free, whereas 1 patient underwent endoscopic submucosal dissection (ESD) as salvage therapy for local recurrence, with no subsequent recurrence. High-risk stage I esophageal cancer patients can be treated radically with RT alone under certain conditions. In the future, to broaden the indications for RT monotherapy to include some degree of advanced cancers, a novel concurrent therapy should be identified.
キーワード esophageal cancer radiation therapy high-risk patient
Amo Type Original Article
発行日 2017-04
出版物タイトル Acta Medica Okayama
71巻
2号
出版者 Okayama University Medical School
開始ページ 127
終了ページ 133
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28420894
タイトル(別表記) Thoracoscopic esophagectomy was effective in a case of lower esophageal stenosis due to recurrence of achalasia after myotomy 40 years previously
著者 桂 佑貴| 白川 靖博| 田邊 俊介| 前田 直見| 野間 和広| 藤原 俊義|
抄録 When planning surgery for achalasia, it is important to plan for adequate myotomy and prevention of reflux. However, achalasia may recur if the procedure was inadequate or in patients with a long-term course. The present case is a 68-year-old woman who underwent myotomy of the lower esophageal sphincter 40 years ago, but recently reported difficulty in swallowing. Dilatation of the thoracic esophagus and stenosis of the abdominal esophagus were identified by examination, and the patient was diagnosed with recurrence of achalasia. After percutaneous endoscopic gastrostomy was performed to recover nutritional status, thoracoscopic esophagectomy was carried out. The patient'spost-operative course was uneventful and oral intake was enabled. At the time of writing, there has been no re-recurrence. There is no standard therapy for post-operative recurrence of achalasia. We believe that thoracoscopic esophagectomy for the recurrence of achalasia is a safe and minimally invasive alternative to conventional surgery.
キーワード 食道アカラシア (achalasia) 再手術 (reoperation) 食道亜全摘 (esophagectomy)
備考 症例報告(Case Reports)
出版物タイトル 岡山医学会雑誌
発行日 2017-04-03
129巻
1号
出版者 岡山医学会
出版者(別表記) Okayama Medical Association
開始ページ 41
終了ページ 44
ISSN 0030-1558
NCID AN00032489
資料タイプ 学術雑誌論文
言語 Japanese
著作権者 Copyright (c) 2017 岡山医学会
論文のバージョン publisher
査読 有り
DOI 10.4044/joma.129.41
Sort Key 8
Eprints Journal Name joma
参考文献 1 ) 鬼丸 学, 井上晴洋 : 食道アカラシアに対する内視鏡的筋層切開術. Modern Physician ( 2014) 34, 478-480. 2 ) Herbella FA, Patti MG : Laparoscopic Heller Myotomy and Fundoplication in Patients with End-Stage Achalasia. World J Surg (2015) 39, 1631-1633. 3 ) Thomas J Watson : Esophagectomy for End-Stage Achalasia. World J Surg ( 2015) 39, 1634-1641. 4 ) 島田英昭, 林 秀樹, 岡住慎一, 落合武徳 : 食道アカラシア手術の最近の進歩. 千葉医学 (2006) 82, 133-138. 5 ) 阿久津泰典, 松原久裕 : 食道アカラシア. 消化器外科 (2009) 32, 1427-1434. 6 ) 小村伸朗, 矢野文章, 坪井一人, 星野真人, 柏木秀幸, 矢永勝彦 : 良性疾患の手術 1 . 食道アカラシアの手術. 手術 (2014) 68, 765-770. 7 ) Mercer CD, Hill LD : Reoperation after failed esophagomyotomy for acharasia. Can J Surg ( 1986) 29, 177-180. 8 ) 太田正穂, 井出博子, 江口礼紀, 中村 努, 菊池哲也, 谷川啓司, 高崎 健 : アカラシア再手術症例の検討. 日臨外会誌 (1998) 59, 1484-1490. 9 ) Loviscek MF, Wright AS, Hinojosa MW, Petersen R, Pajitnov D, Oelschlager BK, Pellegrini CA : Recurrent Dysphagia after Heller Myotomy : Is Esophageactomy Always the Answer? J Am Coll Surg ( 2013) 216, 736-743. 10) Shirakawa Y, Noma K, Maeda N, Katsube R, Tanabe S, Ohara T, Sakurama K, Fujiwara T : Assistant-based standardization of prone position Thoracoscopic esophagectomy. Acta Med Okayama (2014) 68, 2, 111-117.
JaLCDOI 10.18926/AMO/53524
フルテキストURL 69_3_173.pdf
著者 Shirakawa, Yasuhiro| Noma, Kazuhiro| Ohara, Toshiaki| Kashima, Hajime| Maeda, Naoaki| Tanabe, Shunsuke| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
抄録 A chyle leak can occur as a complication after neck or chest surgery. Such a leak prolongs the hospital stay and is sometimes life-threatening. The treatment options are conservative management, interventional radiologic embolization, and surgery. Thoracoscopic ligation of the thoracic duct has emerged as a promising and definitive treatment. The case of a 65-year-old Japanese male patient with a rare congenital right aortic arch (typeⅢB1 of Edwardʼs classification) and a severe chyle leak that occurred after a total pharyngolaryngo-esophagectomy (TPLE) is described. The chyle leak was successfully managed by thoracoscopic ligation of the thoracic duct via a left-side approach with the patient in the prone position.
キーワード chyle leak thoracic duct thoracoscopy prone position
Amo Type Case Report
発行日 2015-06
出版物タイトル Acta Medica Okayama
69巻
3号
出版者 Okayama University Medical School
開始ページ 173
終了ページ 176
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 26101193
Web of Sience KeyUT 000356903000006
著者 Yamada, Eiji| Shirakawa, Yasuhiro| Yamatsuji, Tomoki| Sakuma, Leon| Takaoka, Munenori| Yamada, Takako| Noma, Kazuhiro| Sakurama, Kazufumi| Fujiwara, Yasuhiro| Tanabe, Shunsuke| Nagasaka, Takeshi| Fujiwara, Toshiyoshi| Naomoto, Yoshio|
発行日 2012-12
出版物タイトル Journal of Surgical Research
178巻
2号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/52407
フルテキストURL 68_2_111.pdf
著者 Shirakawa, Yasuhiro| Noma, Kazuhiro| Maeda, Naoaki| Katsube, Ryoichi| Tanabe, Shunsuke| Ohara, Toshiaki| Sakurama, Kazufumi| Fujiwara, Toshiyoshi|
抄録 Thoracoscopic esophagectomy in the prone position (TEPP) might enable solo-surgery in cases requiring resection of the esophagus and the surrounding lymph nodes due to the associated advantages of good exposure of the surgical field and ergonomic considerations for the surgeon. However, no one approach can be for all patients requiring extensive lymphadenectomy. We recently developed an assistant-based procedure to standardize exposure of the surgical field. Patients were divided into 1 of 2 groups:a pre-standardization group (n=37) and a post-standardization group (n=28). The thoracoscopic operative time was significantly shorter (p=0.0037) in the post-standardization group (n=28; 267±31min) than in the pre-standardization group (n=37;301±53min). Further, learning curve analysis using the moving average method showed stabilization of the thoracoscopic operative time after the standardization. No significant differences were found in the number of mediastinal lymph nodes dissected or intraoperative blood loss between the 2 groups. There were also no significant differences in the complication rate. Assistant-based surgery and standardization of the procedure resulted in a well-exposed and safe surgical field. TEPP decreased the operative time, even in patients requiring extensive lymphadenectomy.
キーワード thoracoscopic esophagectomy prone position standardization
Amo Type Original Article
発行日 2014-04
出版物タイトル Acta Medica Okayama
68巻
2号
出版者 Okayama University Medical School
開始ページ 111
終了ページ 117
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24743786
Web of Sience KeyUT 000334652700006
著者 Fujiwara, Y.| Yamada, T.| Naomoto, Y.| Yamatsuji, T.| Shirakawa, Y.| Tanabe, S.| Noma, K.| Kimura, T.| Aoki, H.| Matsukawa, H.| Kimura, M.| Nonaka, Y.| Sasaki, H.| Onoda, T.| Otawa, Y.| Takaoka, M.| Fukazawa, T.| Ohno, Y.| Fujiwara, T.|
発行日 2013-12
出版物タイトル Journal of Hospital Infection
85巻
4号
資料タイプ 学術雑誌論文
タイトル(別表記) A patient with primary malignant melanoma of the esophagus who underwent esophagectomy
フルテキストURL 126_45.pdf
著者 前田 直見| 白川 靖博| 國府島 健| 大原 利章| 田邊 俊輔| 野間 和広| 櫻間 教文| 藤原 俊義|
抄録  We report the case of a 61-old-man with a primary malignant melanoma of the esophagus, an extremely rare and highly aggressive malignancy. He presented with dysphagia, and we performed an upper gastrointestinal endoscopy that detected a tumor in the thoracic part of the esophagus. The biopsy showed malignant melanoma. PET/CT, endoscopy and an esophagogram showed that a 70-mm scaled type 2+1 tumor in the thoracic esophagus and no metastases. We diagnosed a cT3cN0cM0 cStage II tumor. We then performed a subtotal esophagectomy with two-field lymph node dissection and esophagogastrostomy via a retrosternal route. The pathological examination of the resected specimens confirmed that the type 2+1 tumor was PMME (pT2N0M0 pStage II). We administered six courses of postoperative adjuvant chemotherapy with dacarbazine, and the patient has had no recurrence for 17 months after the surgery.
キーワード 食道(esophagus) 悪性黒色腫(malignant melanoma)
備考 症例報告 (Case Reports)
出版物タイトル 岡山医学会雑誌
発行日 2014-04-01
126巻
1号
出版者 岡山医学会
出版者(別表記) Okayama Medical Association
開始ページ 45
終了ページ 48
ISSN 0030-1558
NCID AN00032489
資料タイプ 学術雑誌論文
関連URL http://www.okayama-u.ac.jp/user/oma/
言語 Japanese
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
査読 有り
DOI 10.4044/joma.126.45
Sort Key 9
Eprints Journal Name joma
参考文献 1) Tachimori Y, Ozawa S, Fujishiro M, Matsubara H, Numasaki H, Oyama T, Shinoda M, Toh Y, Udagawa H, Uno T : Comprehensive registry of esophageal cancer in Japan, 2005. Esophagus (2014) 11, 1-20. 2) 山口智弘, 塩飽保博, 小出一真, 栗岡英明, 信谷健太郎, 船津英司, 久津見弘, 藤本荘太郎, 細川洋平 : 食道原発悪性黒色腫の1例と本邦報告例(193例)の検討. 日消誌(2004)10, 1087-1094. 3) 庄村 遊, 村林絋二, 林 仁庸, 中野英明, 上原伸一, 楠田 司, 大橋直樹, 武藤利茂 : 食道原発悪性黒色腫の1例. 日臨外会誌(1995)56, 544-548. 4) Allen AC, Spittz S : Malignant melanoma. A clinicopathological analysis of the criteria for diagnosis and prognosis. Cancer (1953) 6, 1-45. 5) Yonal O, Ibrisim D, Songur Y, Cakaloglu Y, Tuncer K, Kirimlioglu H, Ozdil S : Primary malignant melanoma of the esophagus. Case Rep Gastroenterol (2013) 7, 272-276. 6) Sabanathan S, Eng J, Pradhan GN : Primary malignant melanoma of the esophagus. Am J Gastroenterol (1989) 84, 1475-1481. 7) Volpin E, Sauvanet A, Belghiti J : Primary malignant melanoma of the esophagus : a case report and review of the literature. Dis Esophagus (2002) 15, 244-249. 8) Bisceglia M, Perri F, Tucci A, Tardio M, Panniello G, Vita G, Pasquinelli G : Primary malignant melanoma of the esophagus. Adv Anat Pathol (2011) 18, 235-252. 9) Morita FH, Ribeiro U Jr, Sallum RA, Tacconi MR, Takeda FR, da Rocha JR, Ligabó Gde S, de Melo ES, Pollara WM, Cecconello I : Primary malignant melanoma of the esophagus : a rare and aggressive disease. World J Surg Oncol (2013) 11, 210. 10) Mukaiya M, Hirata K, Tarumi K, Takashima T, Hata F, Denno R, Koito K, Takahashi S, Satoh M : Surgical treatment for recurrent tumors of primary malignant melanoma of the esophagus : a case report and review of the literature. Hepatogastroenterology (1999) 46, 295-298. 11) Iwanuma Y, Tomita N, Amano T, Isayama F, Tsurumaru M, Hayashi T, Kajiyama Y : Current status of primary malignant melanoma of the esophagus : clinical features, pathology, management and prognosis. J Gastroenterol (2012) 47, 21-28.
タイトル(別表記) Complete response of primary esophageal endocrine cell carcinoma resected after neoadjuvant chemotherapy with docetaxel/cisplatin/5-fluorouracil
フルテキストURL 126_39.pdf
著者 前田 直見| 白川 靖博| 國府島 健| 大原 利章| 田邊 俊輔| 野間 和広| 櫻間 教文| 藤原 俊義|
抄録  Esophageal endocrine cell carcinoma is extremely rare. We report a case of esophageal endocrine cell carcinoma showing histological complete response to neoadjuvant chemotherapy with docetaxel/cisplatin/5-fluorouracil (DCF). A 66-year-old man had been experiencing epigastralgia, and a type 2 tumor in the thoracic part of esophagus was detected by upper endoscopy. The biopsy showed endocrine cell carcinoma. PET/CT, endoscopy and an esophagogram showed that the patient had a 70-mm scaled type 2 tumor in the middle thoracic esophagus, and they also revealed lymph node metastases (no. 106recR). We diagnosed a cT3cN1cM0 cStage III tumor. With two courses of DCF treatment, both the primary tumor and lymph node metastases showed a partial response. We performed a subtotal esophagectomy with three-field lymph node dissection. The pathological examination of the resected specimens revealed no malignant cells in the esophagus or lymph nodes, and we concluded that the pathological effect of the DCF treatment was Grade 3.
キーワード 食道癌(esophageal cancer) 内分泌細胞癌(endocrine cell carcinoma) DCF療法(DCF treatment)
備考 症例報告 (Case Reports)
出版物タイトル 岡山医学会雑誌
発行日 2014-04-01
126巻
1号
出版者 岡山医学会
出版者(別表記) Okayama Medical Association
開始ページ 39
終了ページ 43
ISSN 0030-1558
NCID AN00032489
資料タイプ 学術雑誌論文
関連URL http://www.okayama-u.ac.jp/user/oma/
言語 Japanese
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
査読 有り
DOI 10.4044/joma.126.39
Sort Key 8
Eprints Journal Name joma
参考文献 1) Ozawa S, Tachimori Y, Baba H, Fujishiro M, Matsubara H, Numasaki H, Oyama T, Shinoda M, Takeuchi H, Tanaka O, Teshima T, Udagawa H, et al. : Comprehensive registry of esophageal cancer in Japan, 2003. Esophagus (2011) 8, 9-29. 2) Wu Z, Ma JY, Yang JJ, Zhao YF, Zhang SF : Primary small cell carcinoma of esophagus : report of 9 cases and review of literature. World J Gastroenterol (2004) 10, 3680-3682. 3) Hosokawa A, Shimada Y, Matsumura Y, Yamada Y, Muro K, Hamaguchi T, Igaki H, Tachimori Y, Kato H, Shirao K : Small cell carcinoma of the esophagus. Analysis of 14 cases and literature review. Hepatogastroenterology (2005) 52, 1738-1741. 4) Ohmura Y, Takiyama W, Mandai K, Doi T, Nishikawa Y : Small cell carcinoma of the esophagus : a case report. Jpn J Clin Oncol (1997) 27, 95-100. 5) Koide N, Hiraguri M, Kishimoto K, Nakamura T, Adachi W, Miyabayashi H, Terai N, Amano J : Small cell carcinoma of the esophagus with reference to alternating multiagent chemotherapy : report of two cases. Surg Today (2003) 33, 294-298. 6) 杉浦功一, 小澤壯治, 北川雄光, 岡本信彦, 清水芳政, 矢野和仁, 北島政樹 : 食道小細胞癌の1切除例と文献報告例の検討. 日消外会誌(2004)37, 123-129. 7) 橋田秀明, 小室一輝, 岩代 望, 大原正範, 北畠滋郎, 近藤 哲 : 手術と化学療法により長期無再発生存中の食道小細胞癌の1例. 日臨外会誌(2007)68, 1932-1936. 8) Yamashita H, Nakagawa K, Asari T, Murakami N, Igaki H, Okuma K, Ohtomo K : Concurrent chemoradiation alone with curative intent for limited-disease small-cell esophageal cancer in nine Japanese patients. Dis Esophagus (2009) 22, 113-118. 9) Atsumi K, Shioyama Y, Nomoto S, Ohga S, Toba T, Sasaki T, Kunitake N, YoshitakeT, Nakamura K, Honda H : Chemoradiation for small cell esophageal carcinoma : report of 11 cases from multi-instruction experience. J Radiat Res (2010) 51, 15-20. 10) 後藤利博, 渡部宏嗣, 川上高幸, 渡邊雅史, 中野健太郎, 高井敦子, 北澤絵里子, 佐藤新平, 田島康夫, 水口國雄, 菊池健太郎, 宮川 浩 : イリノテカンとシスプラチンの併用化学療法が著効した進行食道小細胞癌の1例. 日消誌(2007)104, 1204-1211. 11) 工藤啓介, 土居浩一, 緒方健一, 平野祐一, 大地哲史 : 集学的治療により長期生存を得た食道小細胞癌の1例. 癌と化療(2010)37, 2403-2405. 12) 佐野 淳, 菊池順子, 小林義輝, 田口 洋, 横山宗伯 : 食道内分泌細胞癌の1切除例. 日消外会誌(2008)41, 1898-1903. 13) 柴田智隆, 片田夏也, 根本昌之, 三重野浩朗, 山下継史, 桜本信一, 菊池史郎, 渡邊昌彦 : 切除可能食道癌に対する術前補助化学療法-JCOG9907からDCF療法へ-. 日外科系連会誌(2012)37, 680-685.
JaLCDOI 10.18926/AMO/49672
フルテキストURL 67_2_123.pdf
著者 Tanabe, Shunsuke| Shirakawa, Yasuhiro| Takehara, Yuko| Maeda, Naoaki| Katsube, Ryoichi| Ohara, Toshiaki| Sakurama, Kazufumi| Noma, Kazuhiro| Fujiwara, Toshiyoshi|
抄録 An 80-year-old woman, who had been administered α-glucosidase inhibitor for diabetes, was brought to the hospital with the sensation of abdominal fullness and pain. Abdominal computed tomography indicated pneumatosis cystoides intestinalis (PCI) in the small intestinal wall, with free air within the abdomen. A blood examination showed no increases in white blood cells or C-reactive protein level. The patientʼs condition improved with conservative therapy. PCI with pneumoperitoneum induced by α-glucosidase inhibitor is rare, with only 27 cases (excluding the present case) reported in Japan to date. In PCI with pneumoperitoneum, differentiation from gastrointestinal perforation is important and following the clinical symptoms over time is vital.
キーワード pneumatosis cystoides intestinalis pneumoperitoneum α-glucosidase inhibitor
Amo Type Case Report
発行日 2013-04
出版物タイトル Acta Medica Okayama
67巻
2号
出版者 Okayama University Medical School
開始ページ 123
終了ページ 128
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 23603930
Web of Sience KeyUT 000317801700008
著者 田辺 俊介| 白川 靖博| 前田 直見| 大原 利章| 野間 和広| 櫻間 教文| 柳井 広之| 山辻 知樹| 猶本 良夫| 藤原 俊義|
発行日 2012-08-01
出版物タイトル 岡山医学会雑誌
124巻
2号
資料タイプ 学術雑誌論文
著者 野間 和広|
発行日 2008-09-30
出版物タイトル
資料タイプ 学位論文