| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Nakamura, Kazufumi| Akagi, Satoshi| Ejiri, Kentaro| Yoshida, Masashi| Miyoshi, Toru| Toh, Norihisa| Nakagawa, Koji| Takaya, Yoichi| Matsubara, Hiromi| Ito, Hiroshi| |
| キーワード | pulmonary arterial hypertension prostaglandin I-2 nitric oxide endothelin |
| 発行日 | 2019-11-23 |
| 出版物タイトル | International Journal of Molecular Sciences |
| 巻 | 20巻 |
| 号 | 23号 |
| 出版者 | MDPI |
| 開始ページ | 5885 |
| ISSN | 1422-0067 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2019 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 31771203 |
| DOI | 10.3390/ijms20235885 |
| Web of Science KeyUT | 000504428300067 |
| 関連URL | isVersionOf https://doi.org/10.3390/ijms20235885 |
| JaLCDOI | 10.18926/AMO/54600 |
|---|---|
| フルテキストURL | 70_5_397.pdf |
| 著者 | Akagi, Satoshi| Nakamura, Kazufumi| Akagi, Teiji| Nakagawa, Koji| Takaya, Yoichi| Sarashina, Toshihiro| Ejiri, Kentaro| Ito, Hiroshi| |
| 抄録 | A treatment strategy for patients with pulmonary hypertension (PH) and atrial septal defect (ASD) remains unclear. This study was designed to evaluate the effects of initial repair of ASD followed by treatment with PH-specific drugs in patients with PH and ASD. Eligible patients receive transcatheter ASD closure followed by treatment with bosentan and sildenafil. Right heart catheterization is performed at baseline and at 12, 24 and 48 weeks. The primary endpoint is change in pulmonary artery pressure and pulmonary vascular resistance from baseline to follow-up. This study should provide valuable information to establish a therapeutic strategy for PH and ASD. |
| キーワード | pulmonary hypertension atrial septal defect repair and treat transcatheter closure |
| Amo Type | Clinical Study Protocols |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-10 |
| 巻 | 70巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 397 |
| 終了ページ | 400 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27777434 |
| Web of Science KeyUT | 000388098700011 |