| フルテキストURL | fulltext20221004-1.pdf Figure_1_20221004-1.jpg Figure_2A_20221004-1.jpg Figure_2B_20221004-1.jpg Figure_2C_20221004-1.jpg Figure_2D_20221004-1.jpg Figure_3_20221004-1.jpg Figure_4_20221004-1.jpg |
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| 著者 | Matsumoto, Kazuyuki| Kato, Hironari| Fujii, Masakuni| Ueki, Toru| Saragai, Yosuke| Tsugeno, Hirofumi| Mannami, Tomohiko| Okada, Hiroyuki| |
| キーワード | benign biliary stricture fully-covered self-expandable metal stent intraductal placement refractory biliary stricture |
| 備考 | This is the peer reviewed version of the following article: [Matsumoto, K, Kato, H, Fujii, M, Ueki, T, Saragai, Y, Tsugeno, H, Efficacy of intraductal placement of nonflared fully-covered metal stent for refractory perihilar benign biliary strictures: A multicenter prospective study with long-term observation. J Hepatobiliary Pancreat Sci. 2022; 29: 1300– 1307. https://doi.org/10.1002/jhbp.1188], which has been published in final form at [https://doi.org/10.1002/jhbp.1188]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext is available in June 2023.| |
| 発行日 | 2022-06-03 |
| 出版物タイトル | Journal of Hepato-Biliary-Pancreatic Sciences |
| 巻 | 29巻 |
| 号 | 12号 |
| 出版者 | Wiley |
| 開始ページ | 1300 |
| 終了ページ | 1307 |
| ISSN | 1868-6974 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 Japanese Society of Hepato-Biliary-Pancreatic Surgery. |
| 論文のバージョン | author |
| PubMed ID | 35657019 |
| DOI | 10.1002/jhbp.1188 |
| Web of Science KeyUT | 000814050800001 |
| 関連URL | isVersionOf https://doi.org/10.1002/jhbp.1188 |
| 著者 | Uchida, Daisuke| Shiraha, Hidenori| Kato, Hironari| Nagahara, Teruya| Iwamuro, Masaya| Kataoka, Junro| Horiguchi, Shigeru| Watanabe, Masami| Takaki, Akinobu| Nouso, Kazuhiro| Nasu, Yasutomo| Yagi, Takahito| Kumon, Hiromi| Yamamoto, Kazuhide| |
|---|---|
| 発行日 | 2014-05 |
| 出版物タイトル | Journal of Gastroenterology and Hepatology |
| 巻 | 29巻 |
| 号 | 5号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/65488 |
|---|---|
| フルテキストURL | 77_3_235.pdf |
| 著者 | Kuraoka, Sakiko| Iwamuro, Masaya| Satomi, Takuya| Yamazaki, Tatsuhiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kato, Hironari| Otsuka, Fumio| Okada, Hiroyuki| |
| 抄録 | Changes in hormone levels in patients with cancer cachexia after anamorelin administration have not been fully investigated. This study aimed to determine how anamorelin affects the endocrine system in patients with gastrointestinal cancer and cachexia. We prospectively enrolled 13 patients and comprehensively investigated their body weight and levels of serum albumin, hemoglobin A1c (HbA1c), and hormones before (week 0) and 3 and 12 weeks after anamorelin administration. The variables were evaluated at week 3 in 9 patients and at week 12 in 5 patients. At week 3, anamorelin administration resulted in body weight gain and increased the levels of growth hormone and HbA1c, as well as insulin-like growth factor-1 standard deviation scores (IGF-1 SD scores). At the same time, negative correlations were observed between ΔIGF-1 SD score and Δthyroidstimulating hormone (TSH) and between ΔIGF-1 SD score and Δfree testosterone. ΔBody weight and ΔIGF-1 SD score correlated positively at week 12. These results suggest that TSH and free testosterone levels can be affected 3 weeks after anamorelin administration; however, those variables tend to return to a state of equilibrium, and anabolic effects of anamorelin appear in long-term (≥ 12 weeks) users. |
| キーワード | anamorelin body weight cancer cachexia endocrine system |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 235 |
| 終了ページ | 241 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357624 |
| Web of Science KeyUT | 001026279600001 |
| JaLCDOI | 10.18926/AMO/65494 |
|---|---|
| フルテキストURL | 77_3_291.pdf |
| 著者 | Himei, Hitomi| Kato, Hironari| Saragai, Yosuke| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| 抄録 | We investigated the efficacy and safety of endoscopic plastic stent (PS) placement for hilar benign biliary strictures (BBSs) and compared cases with PS placement above (inside stent, IS) and across (usual stent, US) the sphincter of Oddi. Patients who underwent initial endoscopic PS placement for hilar BBSs between August 2012 and December 2021 were retrospectively analyzed. Hilar BBSs in 88 patients were investigated. Clinical success was achieved in 81 of these cases (92.0%), including 38 patients in the IS group and 43 patients in the US group. Unexpected stent exchange (uSE) before the first scheduled PS exchange occurred in 18 cases (22.2%). The median time from first stent placement to uSE was 35 days. There was no significant difference in the rate and median time to uSE between the two groups. The rates of adverse events such as pancreatitis or cholangitis in the two groups did not significantly differ. However, the rate of difficult stent removal in the IS group (15.8%) was significantly higher than that in the US group (0%) (p=0.0019). US placement is preferable to IS placement for scheduled stent exchange, as it offers the same effectiveness and risk of adverse events with easier stent removal. |
| キーワード | benign biliary stricture inside stent plastic stent |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 291 |
| 終了ページ | 299 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357630 |
| Web of Science KeyUT | 001026279600007 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kato, Hironari| Matsumoto, Kazuyuki| Okada, Hiroyuki| |
| キーワード | biliary drainage EUS-BD malignant hilar biliary obstruction side-by-side stent-in-stent |
| 発行日 | 2021-09-07 |
| 出版物タイトル | DEN Open |
| 巻 | 2巻 |
| 号 | 1号 |
| 出版者 | Wiley |
| 開始ページ | e33 |
| ISSN | 2692-4609 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 35310763 |
| DOI | 10.1002/deo2.33 |
| Web of Science KeyUT | 001047024900042 |
| 関連URL | isVersionOf https://doi.org/10.1002/deo2.33 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Matsumoto, Kazuyuki| Ohara, Toshiaki| Fujisawa, Masayoshi| Takaki, Akinobu| Takahara, Masahiro| Kato, Hironari| Yoshida, Ryuichi| Umeda, Yuzo| Yagi, Takahito| Matsukawa, Akihiro| Okada, Hiroyuki| |
| キーワード | Programmed death ligand 1 Bile tract neoplasm Biopsy specimen Immunohistochemistry |
| 備考 | The version of record of this article, first published in Journal of Gastrointestinal Surgery, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11605-021-05197-6| |
| 発行日 | 2022-02-08 |
| 出版物タイトル | Journal of Gastrointestinal Surgery |
| 巻 | 26巻 |
| 号 | 6号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 1213 |
| 終了ページ | 1223 |
| ISSN | 1091-255X |
| NCID | AA11494553 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2022 |
| 論文のバージョン | publisher |
| PubMed ID | 35137343 |
| DOI | 10.1007/s11605-021-05197-6 |
| Web of Science KeyUT | 000752761400001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s11605-021-05197-6 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Matsumoto, Kazuyuki| Kato, Hironari| Morimoto, Kosaku| Miyamoto, Kazuya| Saragai, Yosuke| Kawamoto, Hirofumi| Okada, Hiroyuki| |
| キーワード | Bile duct obstruction Neoplasms Endoscopic biliary drainage Bilateral drainage Self-expandable metallic stents |
| 発行日 | 2022-07-19 |
| 出版物タイトル | Gut and Liver |
| 巻 | 17巻 |
| 号 | 1号 |
| 出版者 | The Editorial Office of Gut and Liver |
| 開始ページ | 170 |
| 終了ページ | 178 |
| ISSN | 1976-2283 |
| NCID | AA12329814 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © Gut and Liver. |
| 論文のバージョン | publisher |
| PubMed ID | 35851039 |
| DOI | 10.5009/gnl220012 |
| Web of Science KeyUT | 000830704600001 |
| 関連URL | isVersionOf https://doi.org/10.5009/gnl220012 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Miyamoto, Kazuya| Matsumoto, Kazuyuki| Obata, Taisuke| Sato, Ryosuke| Matsumi, Akihiro| Morimoto, Kosaku| Ogawa, Taiji| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Horiguchi, Shigeru| Tsutsumi, Koichiro| Kato, Hironari| Otsuka, Motoyuki| |
| キーワード | Balloon-assisted endoscopy Propofol Diazepam Sedation |
| 備考 | The version of record of this article, first published in BMC Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12876-023-02936-8| |
| 発行日 | 2023-09-04 |
| 出版物タイトル | BMC Gastroenterology |
| 巻 | 23巻 |
| 号 | 1号 |
| 出版者 | BMC |
| 開始ページ | 296 |
| ISSN | 1471-230X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023. |
| 論文のバージョン | publisher |
| PubMed ID | 37667224 |
| DOI | 10.1186/s12876-023-02936-8 |
| Web of Science KeyUT | 001063014700002 |
| 関連URL | isVersionOf https://doi.org/10.1186/s12876-023-02936-8 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Morimoto, Kosaku| Matsumoto, Kazuyuki| Obata, Taisuke| Oda, Takashi| Miyamoto, Kazuya| Matsumi, Akihiro| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Horiguchi, Shigeru| Tsutsumi, Koichiro| Kato, Hironari| Otsuka, Motoyuki| |
| キーワード | biliary obstruction chemotherapy CT volumetry endoscopic biliary drainage self-expandable metal stent |
| 発行日 | 2023 |
| 出版物タイトル | Therapeutic Advances in Gastroenterology |
| 巻 | 16巻 |
| 出版者 | SAGE Publications |
| ISSN | 1756-283X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s), 2023. |
| 論文のバージョン | publisher |
| PubMed ID | 37900006 |
| DOI | 10.1177/17562848231206980 |
| Web of Science KeyUT | 001097731700001 |
| 関連URL | isVersionOf https://doi.org/10.1177/17562848231206980 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Obata, Taisuke| Tsutsumi, Koichiro| Ueta, Eijiro| Oda, Takashi| Kikuchi, Tatsuya| Ako, Soichiro| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Kato, Hironari| Okada, Hiroyuki| Otsuka, Motoyuki| |
| 発行日 | 2023-12-12 |
| 出版物タイトル | Molecular Therapy Nucleic Acids |
| 巻 | 34巻 |
| 出版者 | Cell Press |
| 開始ページ | 102054 |
| ISSN | 2162-2531 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 38111913 |
| DOI | 10.1016/j.omtn.2023.102054 |
| Web of Science KeyUT | 001146413100001 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.omtn.2023.102054 |
| JaLCDOI | 10.18926/AMO/65974 |
|---|---|
| フルテキストURL | 77_5_517.pdf |
| 著者 | Horiguchi, Shigeru| Matsumoto, Kazuyuki| Morimoto, Kosaku| Matsumi, Akihiro| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Tsutsumi, Koichiro| Kato, Hironari| |
| 抄録 | We investigated the effect of modified FOLFIRINOX (mFFX) in unresectable pancreatic cancer by retrospectively analyzing the cases of 43 patients who underwent BRCA testing (germline, n=11; somatic, n=26; both germline and somatic, n=6). The association between BRCA mutations and therapeutic effect was clarified. Six patients tested positive for germline pathogenic variants. Familial pancreatic cancer (33% vs. 3%, p=0.006) and peritoneal disseminated lesions (66% vs. 8%, p<0.001) were significantly more common in patients with germline pathogenic variants. The partial response (PR) rate was 100% in the germline BRCA-positive patients, and 27% in the germline BRCA-negative patients (p<0.001). The median progression-free survival (PFS) was not reached for any germline BRCA-positive patients but was 9.0 months for the germline BRCA-negative patients (p=0.042). Patients with stage IV BRCA-associated pancreatic cancer had better overall survival than those with non-BRCA-associated pancreatic cancer, although the difference was nonsignificant (not reached vs. 655 days, p=0.061). Our results demonstrate that a PR and prolonged PFS can be expected in germline BRCA-positive patients after treatment with mFFX. Our findings also suggest that germline BRCA pathogenic variants may be useful as biomarkers for the therapeutic effect of mFFX in patients with pancreatic cancer. |
| キーワード | BRCA FOLFIRINOX pancreatic cancer progression-free survival pathogenic variant |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-10 |
| 巻 | 77巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 517 |
| 終了ページ | 525 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37899263 |
| Web of Science KeyUT | 001108661600009 |
