JaLCDOI 10.18926/AMO/65488
フルテキストURL 77_3_235.pdf
著者 Kuraoka, Sakiko| Iwamuro, Masaya| Satomi, Takuya| Yamazaki, Tatsuhiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kato, Hironari| Otsuka, Fumio| Okada, Hiroyuki|
抄録 Changes in hormone levels in patients with cancer cachexia after anamorelin administration have not been fully investigated. This study aimed to determine how anamorelin affects the endocrine system in patients with gastrointestinal cancer and cachexia. We prospectively enrolled 13 patients and comprehensively investigated their body weight and levels of serum albumin, hemoglobin A1c (HbA1c), and hormones before (week 0) and 3 and 12 weeks after anamorelin administration. The variables were evaluated at week 3 in 9 patients and at week 12 in 5 patients. At week 3, anamorelin administration resulted in body weight gain and increased the levels of growth hormone and HbA1c, as well as insulin-like growth factor-1 standard deviation scores (IGF-1 SD scores). At the same time, negative correlations were observed between ΔIGF-1 SD score and Δthyroidstimulating hormone (TSH) and between ΔIGF-1 SD score and Δfree testosterone. ΔBody weight and ΔIGF-1 SD score correlated positively at week 12. These results suggest that TSH and free testosterone levels can be affected 3 weeks after anamorelin administration; however, those variables tend to return to a state of equilibrium, and anabolic effects of anamorelin appear in long-term (≥ 12 weeks) users.
キーワード anamorelin body weight cancer cachexia endocrine system
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-06
77巻
3号
出版者 Okayama University Medical School
開始ページ 235
終了ページ 241
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37357624
Web of Science KeyUT 001026279600001
フルテキストURL fulltext.pdf
著者 Iwamuro, Masaya| Tanaka, Takehiro| Otsuka, Motoyuki|
キーワード autoimmune gastritis esophagogastroduodenoscopy genetic predisposition lymphocyte oxidative stress
発行日 2023-06-21
出版物タイトル Current Issues in Molecular Biology
45巻
7号
出版者 MDPI
開始ページ 5263
終了ページ 5275
ISSN 1467-3037
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 by the authors.
論文のバージョン publisher
PubMed ID 37504250
DOI 10.3390/cimb45070334
Web of Science KeyUT 001035130200001
関連URL isVersionOf https://doi.org/10.3390/cimb45070334
フルテキストURL fulltext.pdf
著者 Hirai, Ryosuke| Kawano, Seiji| Inoo, Shoko| Kuraoka, Sakiko| Okanoue, Shotaro| Satomi, Takuya| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Iwamuro, Masaya| Kawahara, Yoshiro| Okada, Hiroyuki|
キーワード Fibrinolytic agents Endoscopic submucosal resection Postoperative hemorrhage Purinergic P2Y receptor antagonists
発行日 2022-09-29
出版物タイトル Gut and Liver
17巻
3号
出版者 The Editorial Office of Gut and Liver
開始ページ 404
終了ページ 411
ISSN 1976-2283
NCID AA12329814
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Gut and Liver.
論文のバージョン publisher
PubMed ID 36172713
DOI 10.5009/gnl220196
Web of Science KeyUT 000869939200001
関連URL isVersionOf https://doi.org/10.5009/gnl220196
フルテキストURL fulltext.pdf
著者 Kanzaki, Hiromitsu| Horii, Joichiro| Takenaka, Ryuta| Nakagawa, Hiroyuki| Matsueda, Kazuhiro| Tsuzuki, Takao| Kita, Masahide| Yamasaki, Yasushi| Tanaka, Takehiro| Iwamuro, Masaya| Kawano, Seiji| Kawahara, Yoshiro| Tomoda, Jun| Okada, Hiroyuki|
発行日 2022-06-10
出版物タイトル Endoscopy International Open
10巻
06号
出版者 Georg Thieme Verlag KG
開始ページ E712
終了ページ E718
ISSN 2364-3722
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022. The Author(s).
論文のバージョン publisher
PubMed ID 35859656
DOI 10.1055/a-1793-9439
Web of Science KeyUT 000826506700001
関連URL isVersionOf https://doi.org/10.1055/a-1793-9439
フルテキストURL fulltext20230911-01.pdf
著者 Iwamuro, Masaya| Hamada, Kenta| Kawano, Seiji| Kawahara, Yoshiro| Otsuka, Motoyuki|
キーワード Benign diseases Diagnosis Esophagogastroduodenoscopy Non-neoplastic lesions Oral lesions Pharyngolaryngeal lesions
発行日 2023-07-16
出版物タイトル World Journal of Gastrointestinal Endoscopy
15巻
7号
出版者 Baishideng Publishing Group Inc.
開始ページ 496
終了ページ 509
ISSN 1948-5190
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 ©The Author(s) 2023.
論文のバージョン publisher
PubMed ID 37547241
DOI 10.4253/wjge.v15.i7.496
Web of Science KeyUT 001046453000002
関連URL isVersionOf https://doi.org/10.4253/wjge.v15.i7.496
フルテキストURL fulltext.pdf
著者 Tsuge, Mitsuru| Shigehara, Kenji| Uda, Kazuhiro| Kawano, Seiji| Iwamuro, Masaya| Saito, Yukie| Yashiro, Masato| Ikeda, Masanori| Tsukahara, Hirokazu|
キーワード Duodenal ulcer Dupilumab Eosinophilic gastroenteritis Eotaxin-3 Food allergy Interleukin-5 Interleukin-13 Non-esophageal eosinophilic gastrointestinal disorder
備考 The version of record of this article, first published in Allergy, Asthma & Clinical Immunology, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13223-023-00859-3|
発行日 2023-12-05
出版物タイトル Allergy, Asthma & Clinical Immunology
19巻
1号
出版者 BMC
開始ページ 103
ISSN 1710-1492
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023.
論文のバージョン publisher
PubMed ID 38053199
DOI 10.1186/s13223-023-00859-3
Web of Science KeyUT 001113362100001
関連URL isVersionOf https://doi.org/10.1186/s13223-023-00859-3
JaLCDOI 10.18926/AMO/65978
フルテキストURL 77_5_545.pdf
著者 Iwamuro, Masaya| Tanaka, Shouichi| Toyokawa, Tatsuya| Nishimura, Mamoru| Tsuzuki, Takao| Miyahara, Koji| Negishi, Shin| Ohya, Shogen| Tanaka, Takehiro| Otsuka, Motoyuki|
抄録 To determine the endoscopic and clinical features of localized gastric amyloid light-chain (AL) amyloidosis, we retrospectively examined the characteristics of nine patients (eight men and one woman) encountered by the hospitals in our network. Lesions were predominantly flat and depressed with surface vascular dilatation (n=5); others were characterized by subepithelial lesions (n=2), mucosal color change (n=1), and a mass-like morphology with swollen mucosal folds (n=1). Colonoscopy (n=7), video capsule enteroscopy (n=2), serum (n=5) and urine immunoelectrophoresis (n=4), and bone marrow examination (n=3) were performed to exclude involvement of organs other than the stomach. As treatment for gastric lesions of AL amyloidosis, one patient each underwent endoscopic submucosal dissection (n=1) and argon plasma coagulation (n=1), while the remaining seven patients underwent no specific treatment. During a mean follow-up of 4.2 years, one patient died 3.2 years after diagnosis, but the cause of death, which occurred in another hospital, was unknown. The remaining eight patients were alive at the last visit. In conclusion, although localized gastric AL amyloidosis can show various macroscopic features on esophagogastroduodenoscopy, flat, depressed lesions with vascular dilatation on the surface are predominant.
キーワード esophagogastroduodenoscopy gastric lesion amyloidosis light chain
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
77巻
5号
出版者 Okayama University Medical School
開始ページ 545
終了ページ 552
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899266
Web of Science KeyUT 001094245100001
フルテキストURL fulltext.pdf
著者 Iwamuro, Masaya| Takenaka, Ryuta| Toyokawa, Tatsuya| Kita, Masahide| Tsuzuki, Takao| Yoshioka, Masao| Gotoda, Tatsuhiro| Okanoue, Shotaro| Matsubara, Minoru| Sakaguchi, Chihiro| Otsuka, Motoyuki|
備考 The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-52633-z|
発行日 2024-01-25
出版物タイトル Scientific Reports
14巻
1号
出版者 Nature Portfolio
開始ページ 2202
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2024
論文のバージョン publisher
PubMed ID 38273039
DOI 10.1038/s41598-024-52633-z
Web of Science KeyUT 001151714000020
関連URL isVersionOf https://doi.org/10.1038/s41598-024-52633-z
フルテキストURL fulltext.pdf
著者 Kikuchi, Tatsuya| Kono, Yoshiyasu| Nakagawa, Koji| Okada, Hiroyuki| Miyamoto, Masakazu| Takaya, Yoichi| Hirata, Shoichiro| Inoo, Shoko| Kuraoka, Sakiko| Okanoue, Shotaro| Matsueda, Katsunori| Satomi, Takuya| Hamada, Kenta| Iwamuro, Masaya| Kawano, Seiji| Kawahara, Yoshiro|
キーワード antithrombotic drugs gastrointestinal bleeding left atrial appendage closure
発行日 2023-12-27
出版物タイトル JGH Open
8巻
1号
出版者 Wiley
開始ページ e13009
ISSN 2397-9070
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 The Authors.
論文のバージョン publisher
DOI 10.1002/jgh3.13009
Web of Science KeyUT 001131741800001
関連URL isVersionOf https://doi.org/10.1002/jgh3.13009
フルテキストURL fulltext.pdf
著者 Iwamuro, Masaya| Kawano, Seiji| Otsuka, Motoyuki|
キーワード Cowden syndrome Cronkhite-Canada syndrome familial adenomatous polyposis gastric polyposis juvenile polyposis syndrome Peutz-Jeghers syndrome
発行日 2024-01-27
出版物タイトル Gastroenterology Insights
15巻
1号
出版者 MDPI
開始ページ 122
終了ページ 144
ISSN 2036-7414
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 by the authors.
論文のバージョン publisher
DOI 10.3390/gastroent15010009
Web of Science KeyUT 001191406000001
関連URL isVersionOf https://doi.org/10.3390/gastroent15010009
JaLCDOI 10.18926/AMO/65740
フルテキストURL 77_4_347.pdf
著者 Iwamuro, Masaya| Kondo, Takumi| Ennishi, Daisuke| Fujii, Nobuharu| Matsuoka, Ken-ichi| Takahashi, Takahide| Hirabata, Araki| Tanaka, Takehiro| Otsuka, Fumio| Maeda, Yoshinobu| Okada, Hiroyuki|
抄録 The feasibility of lymphocyte isolation and flow cytometry using a single endoscopic biopsy specimen from the gastrointestinal tract of patients who have undergone hematopoietic stem cell transplantation has not been investigated. We acquired 51 endoscopic biopsy specimens from the gastrointestinal tract of 35 patients. We divided the flow cytometry samples into two groups: group A, successful lymphocyte isolation (n=24), and group B, incomplete isolation (n=27). We compared the backgrounds of the samples between the groups to reveal crucial elements in the successful isolation of lymphocytes residing in the gastrointestinal tract. Comparison between the groups revealed lymphocyte isolation success rates differed between biopsy sites. Isolation was most successful in samples from the duodenum (8/9, 88.9%), followed by the ileum (4/8, 50.0%), large intestine (4/11, 36.4%), and stomach (8/23, 34.8%). Tacrolimus was used more frequently in group B (92.6%) than in group A (62.5%) (p=0.015). Logistic regression analysis revealed that isolation from the duodenum or ileum was a significant factor for successful isolation, while tacrolimus use was not statistically significant. In conclusion, the duodenum and ileum are more suitable sites than the stomach and colorectum for acquiring samples for flow cytometry.
キーワード flow cytometry stem cell transplantation transplantation-associated microangiopathy
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-08
77巻
4号
出版者 Okayama University Medical School
開始ページ 347
終了ページ 357
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37635134
Web of Science KeyUT 001163659800002
JaLCDOI 10.18926/AMO/65755
フルテキストURL 77_4_429.pdf
著者 Sasanami, Misa| Iida, Atsuyoshi| Iwamuro, Masaya| Hirai, Ryousuke| Obara, Takashi| Tsukahara, Kohei| Yumoto, Tetsuya| Naito, Hiromichi| Nakao, Atsunori|
抄録 Intramural esophageal dissection (IED), characterized by bleeding into the submucosal space, leads to mucosal separation and dissection. The most prevalent symptoms are sudden chest or retrosternal pain, hematemesis, and dysphagia. Therefore, acute coronary syndrome and aortic dissection are among its most notable differential diagnoses. A 31-year-old pregnant woman presented with acute chest pain, laryngeal discomfort, and hematemesis. Emergency esophagogastroscopy revealed longitudinal mucosal dissection (upper esophagus to esophagogastric junction). The patient was successfully treated by avoiding the ingestion of solid foods. Clinicians should consider a diagnosis of IED for pregnant patients with acute chest pain, especially if hematemesis is present.
キーワード chest pain dysphagia esophageal dissection hematemesis
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2023-08
77巻
4号
出版者 Okayama University Medical School
開始ページ 429
終了ページ 431
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37635144
Web of Science KeyUT 001163659800012
フルテキストURL fulltext.pdf
著者 Iwamuro, Masaya| Takenaka, Ryuta| Miyahara, Koji| Okanoue, Shotaro| Yoshioka, Masao| Sakaguchi, Chihiro| Yamamoto, Kumiko| Kawai, Yoshinari| Toyokawa, Tatsuya| Tanaka, Takehiro| Otsuka, Motoyuki|
キーワード Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue Gastric neoplasms Esophagogastroduodenoscopy t(11;18) translocation, Trisomy 18
備考 The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-55663-9|
発行日 2024-02-29
出版物タイトル Scientific Reports
14巻
1号
出版者 Nature Portfolio
開始ページ 4953
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2024
論文のバージョン publisher
PubMed ID 38418651
DOI 10.1038/s41598-024-55663-9
Web of Science KeyUT 001178149200009
関連URL isVersionOf https://doi.org/10.1038/s41598-024-55663-9
フルテキストURL fulltext.pdf
著者 Kawai, Daisuke| Iwamuro, Masaya| Takenaka, Ryuta| Obata, Taisuke| Yamamoto, Takashi| Hirata, Shoichiro| Miura, Ko| Takemoto, Koji| Tsugeno, Hirofumi| Fujiki, Shigeatsu|
キーワード endoscopic submucosal dissection antithrombotic agents thienopyridine gastric tumor postoperative bleeding delayed bleeding
発行日 2024-03-25
出版物タイトル Journal of Clinical Medicine
13巻
7号
出版者 MDPI
開始ページ 1886
ISSN 2077-0383
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 by the authors.
論文のバージョン publisher
PubMed ID 38610651
DOI 10.3390/jcm13071886
Web of Science KeyUT 001200991800001
関連URL isVersionOf https://doi.org/10.3390/jcm13071886
フルテキストURL fulltext.pdf
著者 Kobashi, Mayu| Ishikawa, Shigenao| Inaba, Tomoki| Iwamuro, Masaya| Aoyama, Yuki| Kagawa, Tomo| Takeuchi, Yasuto| Ando, Midori| Nakamura, Satoko| Okada, Hiroyuki|
キーワード Frozen section Pathological diagnosis Diagnostic accuracy Early gastric cancer Endoscopic submucosal dissection Lateral margin
備考 The version of record of this article, first published in Surgical Endoscopy, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00464-023-10100-2|
発行日 2023-05-22
出版物タイトル Surgical Endoscopy
37巻
9号
出版者 Springer Science and Business Media LLC
開始ページ 6736
終了ページ 6748
ISSN 0930-2794
NCID AA10750363
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023
論文のバージョン publisher
PubMed ID 37217685
DOI 10.1007/s00464-023-10100-2
Web of Science KeyUT 000993678400007
関連URL isVersionOf https://doi.org/10.1007/s00464-023-10100-2