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ID 30802
JaLCDOI
フルテキストURL
著者
Kimura, Nobuhiko Hiroshima City Hospital
Nishioka, Keiko Okayama University
Nishizaki, Kazunori Okayama University Kaken ID
Ogawa, Teruhiro Okayama University
Naitou, Yoshihiro Okayama University
Masuda, Yu Okayama University
抄録

 We studied the clinical efficacy of roxithromycin (RXM) administered at the daily dosage of one tablet (150mg) for 3 months in 30 patients with chronic sinusitis. The effectiveness of this drug was evaluated on a four-point scale. Subjective and objective symptoms disappeared or decreased markedly, especially postnasal drip and nature of discharge in 80 percent or more of the patients. All symptoms significantly decreased (P < 0.001; headache P < 0.05), except for the sensation of foul odor. Symptoms improved even in those cases in which Haemophilus influenzae was detected. It is suggested that RXM produces some clinically beneficial effect through an immunological and or anti-inflammatory mechanisms in addition to its antibiotic effect.

キーワード
roxithromycin
clinical evaluation
chronic sinusitis
long-term
low-dose administration
Amo Type
Article
発行日
1997-02
出版物タイトル
Acta Medica Okayama
51巻
1号
出版者
Okayama University Medical School
開始ページ
33
終了ページ
37
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT