ID | 30802 |
JaLCDOI | |
FullText URL | |
Author |
Kimura, Nobuhiko
Nishioka, Keiko
Ogawa, Teruhiro
Naitou, Yoshihiro
Masuda, Yu
|
Abstract | We studied the clinical efficacy of roxithromycin (RXM) administered at the daily dosage of one tablet (150mg) for 3 months in 30 patients with chronic sinusitis. The effectiveness of this drug was evaluated on a four-point scale. Subjective and objective symptoms disappeared or decreased markedly, especially postnasal drip and nature of discharge in 80 percent or more of the patients. All symptoms significantly decreased (P < 0.001; headache P < 0.05), except for the sensation of foul odor. Symptoms improved even in those cases in which Haemophilus influenzae was detected. It is suggested that RXM produces some clinically beneficial effect through an immunological and or anti-inflammatory mechanisms in addition to its antibiotic effect. |
Keywords | roxithromycin
clinical evaluation
chronic sinusitis
long-term
low-dose administration
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Amo Type | Article
|
Publication Title |
Acta Medica Okayama
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Published Date | 1997-02
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Volume | volume51
|
Issue | issue1
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Publisher | Okayama University Medical School
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Start Page | 33
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End Page | 37
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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File Version | publisher
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Refereed |
True
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PubMed ID | |
Web of Science KeyUT |